DE3014076A1 - Neue heparin-fraktionen mit erhoehter antikoagulans-wirkung - Google Patents
Neue heparin-fraktionen mit erhoehter antikoagulans-wirkungInfo
- Publication number
- DE3014076A1 DE3014076A1 DE19803014076 DE3014076A DE3014076A1 DE 3014076 A1 DE3014076 A1 DE 3014076A1 DE 19803014076 DE19803014076 DE 19803014076 DE 3014076 A DE3014076 A DE 3014076A DE 3014076 A1 DE3014076 A1 DE 3014076A1
- Authority
- DE
- Germany
- Prior art keywords
- heparin
- solution
- sodium chloride
- fractions
- buffered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- 239000013558 reference substance Substances 0.000 description 1
- 239000003998 snake venom Substances 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7912691 | 1979-04-11 | ||
| GB7924816 | 1979-07-17 | ||
| GB8009585 | 1980-03-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3014076A1 true DE3014076A1 (de) | 1980-10-30 |
Family
ID=27260704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19803014076 Withdrawn DE3014076A1 (de) | 1979-04-11 | 1980-04-11 | Neue heparin-fraktionen mit erhoehter antikoagulans-wirkung |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE3014076A1 (enExample) |
| FR (1) | FR2453875A1 (enExample) |
| GB (1) | GB2051103A (enExample) |
| IT (1) | IT1141273B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57134419A (en) * | 1981-02-12 | 1982-08-19 | Eisai Co Ltd | Stable anticoagulant of blood |
| EP1582531A1 (en) | 2004-03-24 | 2005-10-05 | Aventis Pharma S.A. | Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products |
| CN104817651A (zh) * | 2015-05-26 | 2015-08-05 | 苏州鸿洋医药科技有限公司 | 肝素钠的精制工艺 |
| WO2022015794A1 (en) | 2020-07-14 | 2022-01-20 | Optimvia, Llc | Methods for synthesizing non-anticoagulant heparan sulfate |
| AU2020310172A1 (en) | 2019-07-09 | 2022-03-03 | Optimvia Llc | Methods for synthesizing anticoagulant polysaccharides |
| CN113484262B (zh) * | 2021-07-06 | 2023-04-07 | 青岛科技大学 | 一种肝素钠含量测定的方法 |
-
1980
- 1980-04-10 GB GB8011927A patent/GB2051103A/en not_active Withdrawn
- 1980-04-11 IT IT21337/80A patent/IT1141273B/it active
- 1980-04-11 DE DE19803014076 patent/DE3014076A1/de not_active Withdrawn
- 1980-04-11 FR FR8008228A patent/FR2453875A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GB2051103A (en) | 1981-01-14 |
| FR2453875A1 (fr) | 1980-11-07 |
| IT8021337A0 (it) | 1980-04-11 |
| IT1141273B (it) | 1986-10-01 |
| FR2453875B3 (enExample) | 1982-03-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8139 | Disposal/non-payment of the annual fee |