DE2961198D1 - Urea and amide derivatives, their preparation, pharmaceuticals containing them and their use for preparing pharmaceutical compositions - Google Patents

Urea and amide derivatives, their preparation, pharmaceuticals containing them and their use for preparing pharmaceutical compositions

Info

Publication number
DE2961198D1
DE2961198D1 DE7979100647T DE2961198T DE2961198D1 DE 2961198 D1 DE2961198 D1 DE 2961198D1 DE 7979100647 T DE7979100647 T DE 7979100647T DE 2961198 T DE2961198 T DE 2961198T DE 2961198 D1 DE2961198 D1 DE 2961198D1
Authority
DE
Germany
Prior art keywords
urea
preparation
pharmaceutical compositions
amide derivatives
preparing pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979100647T
Other languages
German (de)
English (en)
Inventor
Adrian Prof Dr Marxer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of DE2961198D1 publication Critical patent/DE2961198D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE7979100647T 1978-03-08 1979-03-05 Urea and amide derivatives, their preparation, pharmaceuticals containing them and their use for preparing pharmaceutical compositions Expired DE2961198D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH251978 1978-03-08

Publications (1)

Publication Number Publication Date
DE2961198D1 true DE2961198D1 (en) 1982-01-14

Family

ID=4235609

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979100647T Expired DE2961198D1 (en) 1978-03-08 1979-03-05 Urea and amide derivatives, their preparation, pharmaceuticals containing them and their use for preparing pharmaceutical compositions

Country Status (28)

Country Link
US (2) US4292429A (enExample)
EP (1) EP0004561B1 (enExample)
JP (1) JPS54125668A (enExample)
KR (2) KR820002098B1 (enExample)
AR (2) AR225010A1 (enExample)
AT (1) AT364375B (enExample)
AU (1) AU531006B2 (enExample)
CS (1) CS244656B2 (enExample)
CY (1) CY1304A (enExample)
DD (1) DD142336A5 (enExample)
DE (1) DE2961198D1 (enExample)
DK (1) DK95279A (enExample)
ES (1) ES478342A1 (enExample)
FI (1) FI70708C (enExample)
GB (1) GB2016011B (enExample)
GR (1) GR71998B (enExample)
HK (1) HK80185A (enExample)
HU (1) HU182940B (enExample)
IL (1) IL56797A (enExample)
MY (1) MY8700199A (enExample)
NO (1) NO152606C (enExample)
NZ (1) NZ189841A (enExample)
OA (1) OA06201A (enExample)
PH (1) PH16207A (enExample)
PL (2) PL116762B1 (enExample)
PT (1) PT69314A (enExample)
SU (2) SU845779A3 (enExample)
ZA (1) ZA791062B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338453A (en) 1980-09-17 1982-07-06 The Upjohn Company Aminoalkyl-1,2,4-triazoles
US4353921A (en) * 1981-06-19 1982-10-12 Berlex Laboratories, Inc. Antiarrythmic 1-arylcarbamoylalkyl-2-imidazoline derivatives, composition and method of use
DE3213509A1 (de) * 1982-04-10 1983-10-20 Basf Ag, 6700 Ludwigshafen N-substituierte imidazol-derivate, ihre herstellung, diese enthaltende arzneimittel und ihre verwendung
JPS6133173A (ja) * 1984-07-25 1986-02-17 Torii Yakuhin Kk アミジン化合物
JPS62501922A (ja) * 1984-12-12 1987-07-30 エム・ティー・ディー　メディカル　テクノロジー　アンド　ディベロプメント　リミテッド 病室等の装備方法
GB8906198D0 (en) * 1989-03-17 1989-05-04 Ciba Geigy Ag Compounds
KR20080007640A (ko) * 2005-05-03 2008-01-22 파르마 마르 에스.에이., 소시에다드 유니퍼스널 항암성 테트라하이드로-피리미딘
FR2901273B1 (fr) * 2006-05-19 2010-12-24 Anaconda Pharma Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant
AU2009294225B2 (en) 2008-09-17 2013-07-18 William Kingston Tideway anchor system
BR112012021657B8 (pt) 2010-03-04 2022-06-07 Ea Pharma Co Ltd Composto, agente farmacêutico, agente para conferir kokumi , e, tempero
WO2011108724A1 (ja) * 2010-03-04 2011-09-09 味の素株式会社 糖尿病又は肥満症の予防又は治療剤
CN102924380B (zh) * 2012-11-13 2014-12-31 齐鲁动物保健品有限公司 一种咪唑苯脲的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH234990A (de) * 1938-05-11 1944-10-31 Chem Ind Basel Verfahren zur Darstellung eines neuen therapeutisch wirksamen Amidins.
GB813525A (en) * 1956-07-09 1959-05-21 Socony Mobil Oil Co Inc Fuel oil composition
GB1082964A (en) * 1963-06-25 1967-09-13 Wellcome Found New substituted imidazolines and their preparation and use
US3455940A (en) * 1965-12-07 1969-07-15 Herbert C Stecker Certain halo and dihalo n-substituted salicylamides
GB1174349A (en) * 1966-08-25 1969-12-17 Boehringer Sohn Ingelheim Novel 2-Anilinomethylimidazoline Derivatives and process for the preparation thereof
US3846071A (en) * 1969-02-12 1974-11-05 Petrolite Corp Process of inhibiting corrosion by treatment with phosphate-cyclic amidine salts
NL7415845A (nl) * 1973-12-26 1975-06-30 Upjohn Co Werkwijze voor het bevorderen van de productie van endogene prostaglandinen door zoogdieren, alsmede werkwijze ter bereiding van daarbij te gebruiken preparaten.
US4088766A (en) * 1975-06-25 1978-05-09 The Upjohn Company Urea containing compositions and methods
US4233451A (en) * 1976-05-20 1980-11-11 The Procter & Gamble Company Process for making imidazolinium salts
US4353921A (en) * 1981-06-19 1982-10-12 Berlex Laboratories, Inc. Antiarrythmic 1-arylcarbamoylalkyl-2-imidazoline derivatives, composition and method of use

Also Published As

Publication number Publication date
SU845779A3 (ru) 1981-07-07
OA06201A (fr) 1981-06-30
PL123150B1 (en) 1982-09-30
PL116762B1 (en) 1981-06-30
NO152606C (no) 1985-10-23
AR225010A1 (es) 1982-02-15
HU182940B (en) 1984-03-28
NZ189841A (en) 1982-03-09
US4420619A (en) 1983-12-13
CY1304A (en) 1985-12-06
ES478342A1 (es) 1979-05-16
CS244656B2 (en) 1986-08-14
NO152606B (no) 1985-07-15
NO790765L (no) 1979-09-11
DK95279A (da) 1979-09-09
EP0004561A2 (de) 1979-10-17
FI70708B (fi) 1986-06-26
DD142336A5 (de) 1980-06-18
GB2016011B (en) 1982-08-25
KR830000884B1 (ko) 1983-04-26
US4292429A (en) 1981-09-29
EP0004561B1 (de) 1981-11-04
ZA791062B (en) 1980-03-26
AR227286A1 (es) 1982-10-15
GB2016011A (en) 1979-09-19
MY8700199A (en) 1987-12-31
JPS54125668A (en) 1979-09-29
PL213924A1 (enExample) 1980-02-25
JPS629109B2 (enExample) 1987-02-26
EP0004561A3 (en) 1979-11-14
SU923367A3 (ru) 1982-04-23
GR71998B (enExample) 1983-08-26
IL56797A (en) 1982-09-30
AT364375B (de) 1981-10-12
HK80185A (en) 1985-10-25
ATA171079A (de) 1981-03-15
AU4490079A (en) 1979-09-13
KR820002098B1 (ko) 1982-11-05
AU531006B2 (en) 1983-08-04
FI790740A7 (fi) 1979-09-09
PH16207A (en) 1983-08-05
PT69314A (de) 1979-04-01
FI70708C (fi) 1986-10-06

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee