ES478342A1 - Procedimiento para la obtencion de nuevos compuestos de urea y amido. - Google Patents
Procedimiento para la obtencion de nuevos compuestos de urea y amido.Info
- Publication number
- ES478342A1 ES478342A1 ES478342A ES478342A ES478342A1 ES 478342 A1 ES478342 A1 ES 478342A1 ES 478342 A ES478342 A ES 478342A ES 478342 A ES478342 A ES 478342A ES 478342 A1 ES478342 A1 ES 478342A1
- Authority
- ES
- Spain
- Prior art keywords
- urea
- preparation
- pharmaceutical compositions
- amide derivatives
- preparing pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/22—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Procedimiento para la obtención de nuevos compuestos de urea y amido de fórmula **(Fórmula)** donde R1 y R3 significan un arilo monocíclico, carbocíclico, ó heteroarilo, n representa 0 ó 1, m es 0, 1 ó 2, p es 1 ó 2, R2 significa un átomo de hidrógeno ó alquilo inferior, Alk significa un grupo alquileno inferior, con 2-3 átomos en la línea de cadena, X significa oxígeno, ó azufre e Y es el grupo imino ó un enlace directo, y sus sales, caracterizado porquea)un compuesto de fórmula general II **(Fórmula)** se hace reaccionar con un derivado reactivo del ácido de fórmula general III **(Fórmula)** donde X, Y y R3 tienen los significados arriba indicados, ó b) un compuesto de fórmula general VI **(Fórmula)** donde Rl, R2, n y m tienen los significados arriba indicados, se hace reaccionar con un derivado de dietilen ó bien dipropilentriamina de fórmula general VII**(Fórmula)**donde p. X, Y, Alk y R3 tienen el significado arriba indicado, y en un compuesto obtenido de fórmula general I,encaso deseado, y dentro del márgen de la definición delos productos finales, se introducen, modifican o disocian los sustituyentes, y/o las mezclas de racemato obtenidas se separan en los racematos puros, y/o los racematos obtenidos se separan en los antípodas ópticos, y/o las sales obtenidas se transforman en los compuestos libres o en otras sales, o los compuestos libres en sus sales.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH251978 | 1978-03-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES478342A1 true ES478342A1 (es) | 1979-05-16 |
Family
ID=4235609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES478342A Expired ES478342A1 (es) | 1978-03-08 | 1979-03-06 | Procedimiento para la obtencion de nuevos compuestos de urea y amido. |
Country Status (28)
Country | Link |
---|---|
US (2) | US4292429A (es) |
EP (1) | EP0004561B1 (es) |
JP (1) | JPS54125668A (es) |
KR (2) | KR820002098B1 (es) |
AR (2) | AR225010A1 (es) |
AT (1) | AT364375B (es) |
AU (1) | AU531006B2 (es) |
CS (1) | CS244656B2 (es) |
CY (1) | CY1304A (es) |
DD (1) | DD142336A5 (es) |
DE (1) | DE2961198D1 (es) |
DK (1) | DK95279A (es) |
ES (1) | ES478342A1 (es) |
FI (1) | FI70708C (es) |
GB (1) | GB2016011B (es) |
GR (1) | GR71998B (es) |
HK (1) | HK80185A (es) |
HU (1) | HU182940B (es) |
IL (1) | IL56797A (es) |
MY (1) | MY8700199A (es) |
NO (1) | NO152606C (es) |
NZ (1) | NZ189841A (es) |
OA (1) | OA06201A (es) |
PH (1) | PH16207A (es) |
PL (2) | PL116762B1 (es) |
PT (1) | PT69314A (es) |
SU (2) | SU845779A3 (es) |
ZA (1) | ZA791062B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4338453A (en) | 1980-09-17 | 1982-07-06 | The Upjohn Company | Aminoalkyl-1,2,4-triazoles |
US4353921A (en) * | 1981-06-19 | 1982-10-12 | Berlex Laboratories, Inc. | Antiarrythmic 1-arylcarbamoylalkyl-2-imidazoline derivatives, composition and method of use |
DE3213509A1 (de) * | 1982-04-10 | 1983-10-20 | Basf Ag, 6700 Ludwigshafen | N-substituierte imidazol-derivate, ihre herstellung, diese enthaltende arzneimittel und ihre verwendung |
JPS6133173A (ja) * | 1984-07-25 | 1986-02-17 | Torii Yakuhin Kk | アミジン化合物 |
AU5234886A (en) * | 1984-12-12 | 1986-07-01 | MTD-Produkter I Smaland A.B. | Method of preparing a hospital room or the like |
GB8906198D0 (en) * | 1989-03-17 | 1989-05-04 | Ciba Geigy Ag | Compounds |
EP1879870A1 (en) * | 2005-05-03 | 2008-01-23 | Pharma Mar, S.A. | Antitumoral tetrahydro-pyrimidines |
FR2901273B1 (fr) * | 2006-05-19 | 2010-12-24 | Anaconda Pharma | Inhibiteurs du virus du papillome humain et les compositions pharmaceutiques les contenant |
US8215871B2 (en) | 2008-09-17 | 2012-07-10 | William Kingston | Tideway anchor system |
KR101493717B1 (ko) * | 2010-03-04 | 2015-02-16 | 아지노모토 가부시키가이샤 | 알킬아민 유도체 |
JP5761173B2 (ja) | 2010-03-04 | 2015-08-12 | 味の素株式会社 | 糖尿病又は肥満症の予防又は治療剤 |
CN102924380B (zh) * | 2012-11-13 | 2014-12-31 | 齐鲁动物保健品有限公司 | 一种咪唑苯脲的制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH234990A (de) * | 1938-05-11 | 1944-10-31 | Chem Ind Basel | Verfahren zur Darstellung eines neuen therapeutisch wirksamen Amidins. |
GB813525A (en) * | 1956-07-09 | 1959-05-21 | Socony Mobil Oil Co Inc | Fuel oil composition |
GB1082964A (en) * | 1963-06-25 | 1967-09-13 | Wellcome Found | New substituted imidazolines and their preparation and use |
US3455940A (en) * | 1965-12-07 | 1969-07-15 | Herbert C Stecker | Certain halo and dihalo n-substituted salicylamides |
GB1174349A (en) * | 1966-08-25 | 1969-12-17 | Boehringer Sohn Ingelheim | Novel 2-Anilinomethylimidazoline Derivatives and process for the preparation thereof |
US3846071A (en) * | 1969-02-12 | 1974-11-05 | Petrolite Corp | Process of inhibiting corrosion by treatment with phosphate-cyclic amidine salts |
NL7415845A (nl) * | 1973-12-26 | 1975-06-30 | Upjohn Co | Werkwijze voor het bevorderen van de productie van endogene prostaglandinen door zoogdieren, alsmede werkwijze ter bereiding van daarbij te gebruiken preparaten. |
US4088766A (en) * | 1975-06-25 | 1978-05-09 | The Upjohn Company | Urea containing compositions and methods |
US4233451A (en) * | 1976-05-20 | 1980-11-11 | The Procter & Gamble Company | Process for making imidazolinium salts |
US4353921A (en) * | 1981-06-19 | 1982-10-12 | Berlex Laboratories, Inc. | Antiarrythmic 1-arylcarbamoylalkyl-2-imidazoline derivatives, composition and method of use |
-
1979
- 1979-02-23 US US06/014,661 patent/US4292429A/en not_active Expired - Lifetime
- 1979-03-05 FI FI790740A patent/FI70708C/fi not_active IP Right Cessation
- 1979-03-05 EP EP79100647A patent/EP0004561B1/de not_active Expired
- 1979-03-05 CS CS791460A patent/CS244656B2/cs unknown
- 1979-03-05 DE DE7979100647T patent/DE2961198D1/de not_active Expired
- 1979-03-06 DD DD79211405A patent/DD142336A5/de unknown
- 1979-03-06 PL PL1979213924A patent/PL116762B1/pl unknown
- 1979-03-06 PL PL1979221681A patent/PL123150B1/pl unknown
- 1979-03-06 ES ES478342A patent/ES478342A1/es not_active Expired
- 1979-03-06 IL IL56797A patent/IL56797A/xx unknown
- 1979-03-06 KR KR7900682A patent/KR820002098B1/ko active
- 1979-03-06 OA OA56752A patent/OA06201A/xx unknown
- 1979-03-07 ZA ZA791062A patent/ZA791062B/xx unknown
- 1979-03-07 GB GB7908098A patent/GB2016011B/en not_active Expired
- 1979-03-07 PT PT69314A patent/PT69314A/pt unknown
- 1979-03-07 NO NO790765A patent/NO152606C/no unknown
- 1979-03-07 AU AU44900/79A patent/AU531006B2/en not_active Ceased
- 1979-03-07 SU SU792733999A patent/SU845779A3/ru active
- 1979-03-07 PH PH22264A patent/PH16207A/en unknown
- 1979-03-07 HU HU79CI1920A patent/HU182940B/hu unknown
- 1979-03-07 GR GR58542A patent/GR71998B/el unknown
- 1979-03-07 CY CY1304A patent/CY1304A/xx unknown
- 1979-03-07 DK DK95279A patent/DK95279A/da not_active Application Discontinuation
- 1979-03-07 NZ NZ189841A patent/NZ189841A/xx unknown
- 1979-03-07 AT AT0171079A patent/AT364375B/de not_active IP Right Cessation
- 1979-03-08 JP JP2624579A patent/JPS54125668A/ja active Granted
- 1979-03-18 AR AR275744A patent/AR225010A1/es active
-
1980
- 1980-01-18 SU SU802872253A patent/SU923367A3/ru active
- 1980-07-17 AR AR281806A patent/AR227286A1/es active
-
1981
- 1981-03-25 US US06/247,427 patent/US4420619A/en not_active Expired - Fee Related
-
1982
- 1982-09-08 KR KR1019820004065A patent/KR830000884B1/ko active
-
1985
- 1985-10-17 HK HK801/85A patent/HK80185A/xx unknown
-
1987
- 1987-12-30 MY MY199/87A patent/MY8700199A/xx unknown
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