DE2921058C2 - Vorrichtung zur transkutanen Messung des Sauerstoffpartialdruckes im arteriellen Blut sowie Verfahren zur Herstellung einer Membran für eine solche Vorrichtung - Google Patents
Vorrichtung zur transkutanen Messung des Sauerstoffpartialdruckes im arteriellen Blut sowie Verfahren zur Herstellung einer Membran für eine solche VorrichtungInfo
- Publication number
- DE2921058C2 DE2921058C2 DE2921058A DE2921058A DE2921058C2 DE 2921058 C2 DE2921058 C2 DE 2921058C2 DE 2921058 A DE2921058 A DE 2921058A DE 2921058 A DE2921058 A DE 2921058A DE 2921058 C2 DE2921058 C2 DE 2921058C2
- Authority
- DE
- Germany
- Prior art keywords
- membrane
- layer
- oxygen
- partial pressure
- arterial blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims description 32
- 229910052760 oxygen Inorganic materials 0.000 title claims description 32
- 239000001301 oxygen Substances 0.000 title claims description 32
- 238000005259 measurement Methods 0.000 title claims description 17
- 239000008280 blood Substances 0.000 title claims description 12
- 210000004369 blood Anatomy 0.000 title claims description 12
- 239000012528 membrane Substances 0.000 title description 73
- 238000004519 manufacturing process Methods 0.000 title description 5
- 230000035699 permeability Effects 0.000 description 14
- 239000003792 electrolyte Substances 0.000 description 10
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 description 8
- 238000000576 coating method Methods 0.000 description 8
- 230000004044 response Effects 0.000 description 8
- 239000011248 coating agent Substances 0.000 description 7
- 239000000463 material Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 230000035484 reaction time Effects 0.000 description 6
- OEPOKWHJYJXUGD-UHFFFAOYSA-N 2-(3-phenylmethoxyphenyl)-1,3-thiazole-4-carbaldehyde Chemical compound O=CC1=CSC(C=2C=C(OCC=3C=CC=CC=3)C=CC=2)=N1 OEPOKWHJYJXUGD-UHFFFAOYSA-N 0.000 description 5
- -1 Polyethylene Polymers 0.000 description 5
- 230000002209 hydrophobic effect Effects 0.000 description 5
- 239000004952 Polyamide Substances 0.000 description 4
- 229920002647 polyamide Polymers 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical group FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 description 4
- 239000004831 Hot glue Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 2
- 229920000298 Cellophane Polymers 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 2
- 238000003486 chemical etching Methods 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 239000012212 insulator Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- BQCIDUSAKPWEOX-UHFFFAOYSA-N 1,1-Difluoroethene Chemical compound FC(F)=C BQCIDUSAKPWEOX-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-CUHNMECISA-N D-Cellobiose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-CUHNMECISA-N 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 101100049199 Xenopus laevis vegt-a gene Proteins 0.000 description 1
- 101100049200 Xenopus laevis vegt-b gene Proteins 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229920006026 co-polymeric resin Polymers 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 125000002573 ethenylidene group Chemical group [*]=C=C([H])[H] 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- XUCNUKMRBVNAPB-UHFFFAOYSA-N fluoroethene Chemical compound FC=C XUCNUKMRBVNAPB-UHFFFAOYSA-N 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000003475 lamination Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910000510 noble metal Inorganic materials 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920005672 polyolefin resin Polymers 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 101150068675 vegt gene Proteins 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1477—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means non-invasive
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/403—Cells and electrode assemblies
- G01N27/404—Cells with anode, cathode and cell electrolyte on the same side of a permeable membrane which separates them from the sample fluid, e.g. Clark-type oxygen sensors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Medical Informatics (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Electrochemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6467878A JPS54155682A (en) | 1978-05-29 | 1978-05-29 | Sensor for measuring oxygen concentration in percutaneous blood |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2921058A1 DE2921058A1 (de) | 1979-12-06 |
| DE2921058C2 true DE2921058C2 (de) | 1983-01-20 |
Family
ID=13265058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2921058A Expired DE2921058C2 (de) | 1978-05-29 | 1979-05-23 | Vorrichtung zur transkutanen Messung des Sauerstoffpartialdruckes im arteriellen Blut sowie Verfahren zur Herstellung einer Membran für eine solche Vorrichtung |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS54155682A (OSRAM) |
| DE (1) | DE2921058C2 (OSRAM) |
| FR (1) | FR2427082A1 (OSRAM) |
| GB (1) | GB2021784B (OSRAM) |
| IT (1) | IT1118735B (OSRAM) |
| SE (1) | SE7904602L (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2932739A1 (de) * | 1979-08-13 | 1981-03-12 | Hellige Gmbh, 7800 Freiburg | Messaufnehmer fuer die transcutane bestimmung der konzentration von stoffen, insbesondere des partialdrucks von gasen im blut und im koerpergewebe. |
| JPS57117838A (en) * | 1981-01-12 | 1982-07-22 | Mitsubishi Rayon Co | Electrode for live body |
| DE3111190C2 (de) * | 1981-03-21 | 1983-04-07 | Drägerwerk AG, 2400 Lübeck | Elektrochemischer Meßaufnehmer mit auswechselbarer Membranhalterung |
| US4454643A (en) * | 1981-04-20 | 1984-06-19 | Thoratec Laboratories Corporation | Combination membraning tool, package and calibration unit for eyelid sensor or the like |
| US4442841A (en) * | 1981-04-30 | 1984-04-17 | Mitsubishi Rayon Company Limited | Electrode for living bodies |
| US4476870A (en) * | 1982-03-30 | 1984-10-16 | The United States Of America As Represented By The Department Of Health And Human Services | Fiber optic PO.sbsb.2 probe |
| GB2124387B (en) * | 1982-07-08 | 1986-08-06 | Polystan | Oxygen sensor |
| DK158167C (da) * | 1982-07-14 | 1990-09-17 | Radiometer As | Elektrokemisk maaleelektrodeindretning, membran til en elektrokemisk maaleelektrodeindretning og et membranmonteringssaet til montering af en membran paa en elektrokemisk maaleelektrodeindretning |
| US4534356A (en) * | 1982-07-30 | 1985-08-13 | Diamond Shamrock Chemicals Company | Solid state transcutaneous blood gas sensors |
| GB2140563B (en) * | 1983-04-27 | 1987-03-04 | Critikon Inc | Method and apparatus for zero calibration of oxygen-sensing polarographic devices |
| JPH06264461A (ja) * | 1993-03-15 | 1994-09-20 | Naoyuki Hashimoto | 石積み式擁壁の形成工法及びその工法に用いるアンカーボルト |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3718563A (en) * | 1971-02-22 | 1973-02-27 | Beckman Instruments Inc | Polarographic sensor and membrane therefor |
| DE2255879B2 (de) * | 1972-11-15 | 1976-05-26 | L. Eschweiler & Co, 2300 Kiel | Vorrichtung zur percutanen bestimmung der perfusionseffizienz |
| DE2539771A1 (de) * | 1975-09-06 | 1977-03-17 | Hellige Gmbh | Polarographischer messaufnehmer vom clark-typ zur bestimmung des partialdruckes von gasen, insbesondere von sauerstoff in fluessigkeiten |
| DE2628288A1 (de) * | 1976-06-24 | 1977-12-29 | Draegerwerk Ag | Messaufnehmer fuer die bestimmung des gehaltes von gasen in fluessigkeiten, insbesondere fuer die transcutane blutgasbestimmung |
-
1978
- 1978-05-29 JP JP6467878A patent/JPS54155682A/ja active Granted
-
1979
- 1979-05-23 DE DE2921058A patent/DE2921058C2/de not_active Expired
- 1979-05-28 SE SE7904602A patent/SE7904602L/xx not_active Application Discontinuation
- 1979-05-28 FR FR7913522A patent/FR2427082A1/fr active Granted
- 1979-05-28 IT IT7968148A patent/IT1118735B/it active
- 1979-05-29 GB GB7918560A patent/GB2021784B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2427082A1 (fr) | 1979-12-28 |
| IT1118735B (it) | 1986-03-03 |
| JPS54155682A (en) | 1979-12-07 |
| FR2427082B1 (OSRAM) | 1984-06-08 |
| DE2921058A1 (de) | 1979-12-06 |
| GB2021784A (en) | 1979-12-05 |
| SE7904602L (sv) | 1979-11-30 |
| JPS5616652B2 (OSRAM) | 1981-04-17 |
| GB2021784B (en) | 1982-10-13 |
| IT7968148A0 (it) | 1979-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OAP | Request for examination filed | ||
| OD | Request for examination | ||
| D2 | Grant after examination | ||
| 8363 | Opposition against the patent | ||
| 8330 | Complete renunciation |