DE2839668A1 - Als antibiotika wirksame saframycine a, b, c, d und e und verfahren zu ihrer herstellung - Google Patents
Als antibiotika wirksame saframycine a, b, c, d und e und verfahren zu ihrer herstellungInfo
- Publication number
- DE2839668A1 DE2839668A1 DE19782839668 DE2839668A DE2839668A1 DE 2839668 A1 DE2839668 A1 DE 2839668A1 DE 19782839668 DE19782839668 DE 19782839668 DE 2839668 A DE2839668 A DE 2839668A DE 2839668 A1 DE2839668 A1 DE 2839668A1
- Authority
- DE
- Germany
- Prior art keywords
- saframycin
- values
- color
- methanol
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C12R2001/56—Streptomyces lavendulae
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP52109692A JPS5937952B2 (ja) | 1977-09-12 | 1977-09-12 | 抗生物質サフラマイシンa,b,c,d,eおよびその製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2839668A1 true DE2839668A1 (de) | 1979-03-22 |
| DE2839668C2 DE2839668C2 (enExample) | 1987-08-13 |
Family
ID=14516767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19782839668 Granted DE2839668A1 (de) | 1977-09-12 | 1978-09-12 | Als antibiotika wirksame saframycine a, b, c, d und e und verfahren zu ihrer herstellung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4248863A (enExample) |
| JP (1) | JPS5937952B2 (enExample) |
| DE (1) | DE2839668A1 (enExample) |
| FR (1) | FR2402665A1 (enExample) |
| GB (1) | GB2003853B (enExample) |
| IT (1) | IT1108793B (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6809099B2 (en) | 2000-11-03 | 2004-10-26 | President And Fellows Of Harvard College | Saframycins, analogues and uses thereof |
| US7183054B2 (en) | 2003-06-03 | 2007-02-27 | President And Fellows Of Harvard College | Assay for identifying biological targets of polynucleotide-binding compounds |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56135486A (en) * | 1980-03-26 | 1981-10-22 | Tadashi Arai | Antibiotic saframycin s and its preparative method |
| JPS6041489A (ja) * | 1983-08-12 | 1985-03-05 | Kyowa Hakko Kogyo Co Ltd | 新規生理活性物質k―252 |
| JPS6158593A (ja) * | 1984-08-30 | 1986-03-25 | Tadashi Arai | 新規サフラマイシンa誘導体およびその製造法 |
| EP0262085A1 (de) * | 1986-08-15 | 1988-03-30 | Gesellschaft für Biotechnologische Forschung mbH (GBF) | Antibiotika aus Myxococcus |
| US6124292A (en) | 1998-09-30 | 2000-09-26 | President And Fellows Of Harvard College | Synthetic analogs of ecteinascidin-743 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR338M (fr) * | 1960-08-26 | 1961-03-27 | Lilly Co Eli | Nouvel antibiotique. |
| DE1208449B (de) * | 1963-03-27 | 1966-01-05 | Ciba Geigy | Verfahren zur Herstellung des Antibiotikums Ussamycin |
| JPS5238094A (en) * | 1975-09-19 | 1977-03-24 | Tadashi Arai | Method of producing antibiotics, mimosamycin and chlorocarcin a, b, c |
| US4127446A (en) * | 1975-09-07 | 1978-11-28 | Tadashi Arai | Process for producing antibiotics mimosamycin and chlorocarcins A, B and C |
| US4081531A (en) * | 1975-09-19 | 1978-03-28 | Tadashi Arai | Antibiotic mimosamycin |
-
1977
- 1977-09-12 JP JP52109692A patent/JPS5937952B2/ja not_active Expired
-
1978
- 1978-09-06 US US05/940,031 patent/US4248863A/en not_active Expired - Lifetime
- 1978-09-12 DE DE19782839668 patent/DE2839668A1/de active Granted
- 1978-09-12 FR FR7826167A patent/FR2402665A1/fr active Granted
- 1978-09-12 GB GB7836509A patent/GB2003853B/en not_active Expired
- 1978-09-12 IT IT69099/78A patent/IT1108793B/it active
Non-Patent Citations (5)
| Title |
|---|
| Bergey's Determinative Bacteriology, 8. Aufl., 1974 * |
| Color Harmony Manual, Container's Corporation of America, 1958 * |
| Descriptive Color Name Dictionary, Container's Corporation of America, 1950 * |
| International J. Systematic Bacteriol. 16, 1966, 313-340 * |
| WALKSMAN, S.A.: The Actinomyces, Vol. 2, 1959 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6809099B2 (en) | 2000-11-03 | 2004-10-26 | President And Fellows Of Harvard College | Saframycins, analogues and uses thereof |
| US7122549B2 (en) | 2000-11-03 | 2006-10-17 | President And Fellows Of Harvard College | Saframycins, analogues and uses thereof |
| US7183054B2 (en) | 2003-06-03 | 2007-02-27 | President And Fellows Of Harvard College | Assay for identifying biological targets of polynucleotide-binding compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2402665A1 (fr) | 1979-04-06 |
| IT1108793B (it) | 1985-12-09 |
| GB2003853A (en) | 1979-03-21 |
| US4248863A (en) | 1981-02-03 |
| GB2003853B (en) | 1982-04-21 |
| JPS5444098A (en) | 1979-04-07 |
| DE2839668C2 (enExample) | 1987-08-13 |
| JPS5937952B2 (ja) | 1984-09-12 |
| IT7869099A0 (it) | 1978-09-12 |
| FR2402665B1 (enExample) | 1981-06-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE2634499C2 (de) | Tylosin-Acylderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende pharmazeutische Zubereitungen und Tierfutterzubereitungen | |
| DE2347682A1 (de) | Rapamycin und seine herstellung | |
| DE3887820T2 (de) | Antibiotika, Benanomicine A und B und Dexylosylbenanomicin B, ihre Herstellung und Verwendung. | |
| DE2743654C3 (enExample) | ||
| CH630957A5 (de) | Verfahren zur herstellung von neuen antibiotischen verbindungen auf basis eines bohemsaeurekomplexes. | |
| DE60006690T2 (de) | Antibiotische caprazamycine und verfahren zu deren herstellung | |
| DE2167325C2 (de) | Antibiotikum A-201B und Verfahren zu seiner Herstellung | |
| DE2715255C3 (de) | Anthracyclinglykoside MA 144-M, und MA 144-M2 und deren Salze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen | |
| DE2839668A1 (de) | Als antibiotika wirksame saframycine a, b, c, d und e und verfahren zu ihrer herstellung | |
| DE2004686C3 (de) | Makrolid-Antibioticum SF-837 und dessen Diacetylderivat und deren pharmakologisch nichtgiftige Säureanlagerungssalze sowie Verfahren zur Herstellung des Antibioticums SF-837 | |
| DE2028403C3 (de) | Pepstatin | |
| DD234031A5 (de) | Verfahren zur herstellung von neuen antibiotika ll-d 42067alpha und ll-d 42067beta | |
| CH631740A5 (en) | Process for the preparation of maytansinol and its derivatives | |
| DE2921148A1 (de) | Neue metaboliten, ihre herstellung und verwendung | |
| CH646712A5 (de) | Istamycine und deren herstellung. | |
| EP0236894B1 (de) | Efomycin G, seine Herstellung und seine Verwendung als Leistungsförderer bei Tieren | |
| DE3136675A1 (de) | Neues peptid und dessen herstellung | |
| DE3407979C2 (enExample) | ||
| DE1770441C2 (de) | Neue Antibiotika und Verfahren zu ihrer Herstellung | |
| DE2039990C2 (de) | Neue Antibiotika B-5050 A bis F (Maridomycin I bis VI), Verfahren zu ihrer Herstellung und ihre pharmazeutische Zubereitung | |
| DE2746209A1 (de) | Neues antibiotikum und verfahren zu dessen herstellung | |
| DE2946793C2 (de) | 4-O-Desmethyl-11-desoxy-anthracyclinglycoside, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende pharmazeutische Zusammensetzungen | |
| CH633964A5 (de) | Verfahren zur herstellung von pepsin-inhibitoren. | |
| DE2510868C3 (de) | Nanaomycin A und Verfahren zur Herstellung der Antibiorica Nanaomycin A und Nanaomycin B | |
| DE2746252A1 (de) | Antibiotikum c-15003 enthaltendes arzneimittel zur behandlung von tumore aufweisenden warmbluetern |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8128 | New person/name/address of the agent |
Representative=s name: STREHL, P., DIPL.-ING. DIPL.-WIRTSCH.-ING. SCHUEBE |
|
| 8181 | Inventor (new situation) |
Free format text: ERFINDER IST ANMELDER |
|
| 8110 | Request for examination paragraph 44 | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |