DE2748564C2 - Verfahren zur Gewinnung von Informationen über die Eigenschaften von in einer Flüssigkeit suspendierten Teilchen sowie Vorrichtung zur Ausführung dieses Verfahrens - Google Patents
Verfahren zur Gewinnung von Informationen über die Eigenschaften von in einer Flüssigkeit suspendierten Teilchen sowie Vorrichtung zur Ausführung dieses VerfahrensInfo
- Publication number
- DE2748564C2 DE2748564C2 DE2748564A DE2748564A DE2748564C2 DE 2748564 C2 DE2748564 C2 DE 2748564C2 DE 2748564 A DE2748564 A DE 2748564A DE 2748564 A DE2748564 A DE 2748564A DE 2748564 C2 DE2748564 C2 DE 2748564C2
- Authority
- DE
- Germany
- Prior art keywords
- particles
- particle
- suspension
- flow
- properties
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002245 particle Substances 0.000 title claims description 72
- 239000007788 liquid Substances 0.000 title claims description 12
- 238000000034 method Methods 0.000 title claims description 9
- 238000001514 detection method Methods 0.000 claims description 45
- 239000000758 substrate Substances 0.000 claims description 18
- 239000000725 suspension Substances 0.000 claims description 17
- 230000002123 temporal effect Effects 0.000 claims description 13
- 238000005259 measurement Methods 0.000 claims description 9
- 239000006194 liquid suspension Substances 0.000 claims description 3
- 101100346656 Drosophila melanogaster strat gene Proteins 0.000 claims description 2
- 101150107341 RERE gene Proteins 0.000 claims 1
- 230000000704 physical effect Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000000875 corresponding effect Effects 0.000 description 2
- 101150100859 45 gene Proteins 0.000 description 1
- 101100400378 Mus musculus Marveld2 gene Proteins 0.000 description 1
- 101150049168 Nisch gene Proteins 0.000 description 1
- WYTGDNHDOZPMIW-RCBQFDQVSA-N alstonine Natural products C1=CC2=C3C=CC=CC3=NC2=C2N1C[C@H]1[C@H](C)OC=C(C(=O)OC)[C@H]1C2 WYTGDNHDOZPMIW-RCBQFDQVSA-N 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- 235000013405 beer Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
- G01N15/1427—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement with the synchronisation of components, a time gate for operation of components, or suppression of particle coincidences
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
- G01N2001/282—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on with mapping; Identification of areas; Spatial correlated pattern
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1477—Multiparameters
Landscapes
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/736,546 US4184766A (en) | 1976-10-28 | 1976-10-28 | Method and apparatus for correlating measurements of tandem sensing zones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2748564A1 DE2748564A1 (de) | 1978-09-14 |
| DE2748564C2 true DE2748564C2 (de) | 1986-02-06 |
Family
ID=24960300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2748564A Expired DE2748564C2 (de) | 1976-10-28 | 1977-10-28 | Verfahren zur Gewinnung von Informationen über die Eigenschaften von in einer Flüssigkeit suspendierten Teilchen sowie Vorrichtung zur Ausführung dieses Verfahrens |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US4184766A (enExample) |
| JP (1) | JPS5360287A (enExample) |
| DE (1) | DE2748564C2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10304653A1 (de) * | 2003-02-05 | 2004-08-19 | Evotec Technologies Gmbh | Mehrparametrige Detektion in einem fluidischen Mikrosystem |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4361400A (en) * | 1980-11-26 | 1982-11-30 | The United States Of America As Represented By The United States Department Of Energy | Fluidic assembly for an ultra-high-speed chromosome flow sorter |
| CA1174073A (en) * | 1981-01-16 | 1984-09-11 | Thomas M. Campbell | Methods and apparatus for well investigation and development |
| JPS61270639A (ja) * | 1985-05-25 | 1986-11-29 | Japan Spectroscopic Co | フロ−サイトメ−タ |
| JPS61283848A (ja) * | 1985-06-10 | 1986-12-13 | Japan Spectroscopic Co | フロ−サイトメ−タ |
| US4987539A (en) * | 1987-08-05 | 1991-01-22 | Stanford University | Apparatus and method for multidimensional characterization of objects in real time |
| JP3121849B2 (ja) * | 1991-02-27 | 2001-01-09 | シスメックス株式会社 | フローイメージサイトメータ |
| US5649576A (en) * | 1996-02-26 | 1997-07-22 | Pharmacopeia, Inc. | Partitioning device |
| US6175227B1 (en) | 1997-07-03 | 2001-01-16 | Coulter International Corp. | Potential-sensing method and apparatus for sensing and characterizing particles by the Coulter principle |
| US7410063B1 (en) * | 1999-08-09 | 2008-08-12 | The United States Of America As Represented By The Secretary Of The Army | Method and system for sorting particles sampled from air |
| JP4057422B2 (ja) * | 2001-01-25 | 2008-03-05 | プレシジョン・システム・サイエンス株式会社 | 微小物識別装置およびその識別方法 |
| EP2732395B1 (en) | 2011-08-25 | 2018-04-04 | Sony Corporation | Compensation of motion-related error in a stream of moving mirco-entities |
| TWI475214B (zh) * | 2012-06-22 | 2015-03-01 | Wistron Corp | 生物檢體檢測裝置及生物檢體檢測方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3822095A (en) * | 1972-08-14 | 1974-07-02 | Block Engineering | System for differentiating particles |
| US3924947A (en) * | 1973-10-19 | 1975-12-09 | Coulter Electronics | Apparatus for preservation and identification of particles analyzed by flow-through apparatus |
| US3976862A (en) * | 1975-03-18 | 1976-08-24 | Block Engineering, Inc. | Flow stream processor |
-
1976
- 1976-10-28 US US05/736,546 patent/US4184766A/en not_active Expired - Lifetime
-
1977
- 1977-10-25 JP JP12732877A patent/JPS5360287A/ja active Granted
- 1977-10-28 DE DE2748564A patent/DE2748564C2/de not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10304653A1 (de) * | 2003-02-05 | 2004-08-19 | Evotec Technologies Gmbh | Mehrparametrige Detektion in einem fluidischen Mikrosystem |
| DE10304653B4 (de) * | 2003-02-05 | 2005-01-27 | Evotec Technologies Gmbh | Mehrparametrige Detektion in einem fluidischen Mikrosystem |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5643496B2 (enExample) | 1981-10-13 |
| JPS5360287A (en) | 1978-05-30 |
| US4184766A (en) | 1980-01-22 |
| DE2748564A1 (de) | 1978-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OD | Request for examination | ||
| 8161 | Application of addition to: |
Ref document number: 2449701 Country of ref document: DE Format of ref document f/p: P |
|
| AF | Is addition to no. |
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| AF | Is addition to no. |
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| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8340 | Patent of addition ceased/non-payment of fee of main patent |