DE2731724A1 - Neue cephalosporinderivate, verfahren zu deren herstellung und daraus hergestellte arzneimittel - Google Patents

Neue cephalosporinderivate, verfahren zu deren herstellung und daraus hergestellte arzneimittel

Info

Publication number
DE2731724A1
DE2731724A1 DE19772731724 DE2731724A DE2731724A1 DE 2731724 A1 DE2731724 A1 DE 2731724A1 DE 19772731724 DE19772731724 DE 19772731724 DE 2731724 A DE2731724 A DE 2731724A DE 2731724 A1 DE2731724 A1 DE 2731724A1
Authority
DE
Germany
Prior art keywords
stands
formula
acid
pharmaceutically acceptable
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19772731724
Other languages
German (de)
English (en)
Inventor
Seiji Iimura
Hajime Kamachi
Takayuki Naito
Jun Okumura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/771,859 external-priority patent/US4103085A/en
Priority claimed from US05/777,986 external-priority patent/US4112228A/en
Priority claimed from US05/788,056 external-priority patent/US4104469A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DE2731724A1 publication Critical patent/DE2731724A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34Oxygen atoms
DE19772731724 1976-07-13 1977-07-13 Neue cephalosporinderivate, verfahren zu deren herstellung und daraus hergestellte arzneimittel Withdrawn DE2731724A1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70522676A 1976-07-13 1976-07-13
US05/771,859 US4103085A (en) 1977-02-24 1977-02-24 7-(Syn-α-alkoxy-iminofurylacetamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids
US05/777,986 US4112228A (en) 1976-07-13 1977-03-16 7-(D-α-Hydroxy-2-arylacetamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo-[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids and derivatives
US05/788,056 US4104469A (en) 1977-04-15 1977-04-15 7-(Syn-α-alkoxy-iminofuryl)acetamido-3-(2-methyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids

Publications (1)

Publication Number Publication Date
DE2731724A1 true DE2731724A1 (de) 1978-01-19

Family

ID=27505490

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772731724 Withdrawn DE2731724A1 (de) 1976-07-13 1977-07-13 Neue cephalosporinderivate, verfahren zu deren herstellung und daraus hergestellte arzneimittel

Country Status (16)

Country Link
JP (1) JPS5328191A (ru)
AU (1) AU511805B2 (ru)
BE (1) BE856785A (ru)
CA (1) CA1142918A (ru)
CH (1) CH640239A5 (ru)
DE (1) DE2731724A1 (ru)
DK (1) DK143344C (ru)
FI (1) FI772179A (ru)
FR (1) FR2358411A1 (ru)
GB (1) GB1561236A (ru)
GR (1) GR81280B (ru)
IE (1) IE45548B1 (ru)
LU (1) LU77756A1 (ru)
NL (1) NL7707820A (ru)
SE (2) SE7708053L (ru)
YU (1) YU171977A (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228061A3 (en) * 1985-12-23 1988-12-14 Takeda Chemical Industries, Ltd. Cephem compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids

Also Published As

Publication number Publication date
LU77756A1 (ru) 1978-02-08
GB1561236A (en) 1980-02-13
CH640239A5 (en) 1983-12-30
FR2358411A1 (fr) 1978-02-10
DK143344C (da) 1981-12-14
FI772179A (ru) 1978-01-14
IE45548B1 (en) 1982-09-22
JPS5328191A (en) 1978-03-16
CA1142918A (en) 1983-03-15
SE8205482L (sv) 1982-09-24
SE8205482D0 (sv) 1982-09-24
YU171977A (en) 1982-06-30
NL7707820A (nl) 1978-01-17
AU2698277A (en) 1979-01-18
GR81280B (ru) 1984-12-11
FR2358411B1 (ru) 1981-06-12
SE7708053L (sv) 1978-01-14
IE45548L (en) 1978-01-13
AU511805B2 (en) 1980-09-04
DK143344B (da) 1981-08-10
BE856785A (fr) 1978-01-13
DK312677A (da) 1978-01-14

Similar Documents

Publication Publication Date Title
DE2727753C2 (ru)
DE2462736C2 (de) 7-Aminothiazolylacetamido-3-cephem-4-carbonsäuren und Verfahren zur Herstellung derselben
DE2336345C2 (de) Cephalosporinverbindungen, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CH624119A5 (ru)
DE2633193A1 (de) Neue, antibakteriell wirksame verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2356388A1 (de) Cephalosporine und verfahren zu ihrer herstellung
DE2158855A1 (de) Heterocyclisch substituierte Ureidocephalosporine
DE2538804C2 (de) Cephalosporinderivate, Verfahren zu ihrer Herstellung und sie enthaltende Mittel
DD282691A5 (de) Verfahren zur herstellung von cephalosporin
DE2945248A1 (de) Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
DE2225694A1 (de) Cephalosporinverbindungen und Ver fahren zu deren Herstellung
CH626370A5 (en) Process for the preparation of the syn isomer or of a mixture of syn and anti isomers of 7beta-acylamidoceph-3-em-4-carboxylic acids with antibiotic activity
CH636879A5 (de) Verfahren zur herstellung 7-substituierter aminoacetamido-oxadethia-cephalosporine.
DE2715038A1 (de) Neue antibakterielle verbindungen
DE2234280B2 (de) Cephalosporinverbindungen und Verfahren zu deren Herstellung
DE2731724A1 (de) Neue cephalosporinderivate, verfahren zu deren herstellung und daraus hergestellte arzneimittel
EP0035161B1 (de) Cephalosporine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3041160A1 (de) 1-oxadethia-cephalosporin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende antibakterielle mittel
DE2805590A1 (de) Pharmakologisch wirksame cephalosporinsaeurederivate, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
CH630922A5 (de) Verfahren zur herstellung neuer penicillin-derivate.
CH638812A5 (en) Process for the preparation of cephalosporin derivatives
EP0054677B1 (de) Neue Cephalosporine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2356704A1 (de) 3-(heterocyclische-thiomethyl)-cephalosporinverbindungen und ihre pharmakologisch vertraeglichen salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate
DE2336344A1 (de) Penicillin- und cephalosporin-rsulfoxide, ihre salze und ester, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2805608A1 (de) Neue cephalosporin-derivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Legal Events

Date Code Title Description
8141 Disposal/no request for examination