CH640239A5 - Process for the preparation of novel cephem-4-carboxylic acid compounds - Google Patents

Process for the preparation of novel cephem-4-carboxylic acid compounds Download PDF

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Publication number
CH640239A5
CH640239A5 CH868077A CH868077A CH640239A5 CH 640239 A5 CH640239 A5 CH 640239A5 CH 868077 A CH868077 A CH 868077A CH 868077 A CH868077 A CH 868077A CH 640239 A5 CH640239 A5 CH 640239A5
Authority
CH
Switzerland
Prior art keywords
acid
triazolo
dihydro
pyridazin
cephem
Prior art date
Application number
CH868077A
Other languages
German (de)
English (en)
Inventor
Takayuki Naito
Jun Okumura
Hajime Kamachi
Seiji Iimura
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/771,859 external-priority patent/US4103085A/en
Priority claimed from US05/777,986 external-priority patent/US4112228A/en
Priority claimed from US05/788,056 external-priority patent/US4104469A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CH640239A5 publication Critical patent/CH640239A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34Oxygen atoms
CH868077A 1976-07-13 1977-07-13 Process for the preparation of novel cephem-4-carboxylic acid compounds CH640239A5 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70522676A 1976-07-13 1976-07-13
US05/771,859 US4103085A (en) 1977-02-24 1977-02-24 7-(Syn-α-alkoxy-iminofurylacetamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids
US05/777,986 US4112228A (en) 1976-07-13 1977-03-16 7-(D-α-Hydroxy-2-arylacetamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo-[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids and derivatives
US05/788,056 US4104469A (en) 1977-04-15 1977-04-15 7-(Syn-α-alkoxy-iminofuryl)acetamido-3-(2-methyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids

Publications (1)

Publication Number Publication Date
CH640239A5 true CH640239A5 (en) 1983-12-30

Family

ID=27505490

Family Applications (1)

Application Number Title Priority Date Filing Date
CH868077A CH640239A5 (en) 1976-07-13 1977-07-13 Process for the preparation of novel cephem-4-carboxylic acid compounds

Country Status (16)

Country Link
JP (1) JPS5328191A (ru)
AU (1) AU511805B2 (ru)
BE (1) BE856785A (ru)
CA (1) CA1142918A (ru)
CH (1) CH640239A5 (ru)
DE (1) DE2731724A1 (ru)
DK (1) DK143344C (ru)
FI (1) FI772179A (ru)
FR (1) FR2358411A1 (ru)
GB (1) GB1561236A (ru)
GR (1) GR81280B (ru)
IE (1) IE45548B1 (ru)
LU (1) LU77756A1 (ru)
NL (1) NL7707820A (ru)
SE (2) SE7708053L (ru)
YU (1) YU171977A (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228061A3 (en) * 1985-12-23 1988-12-14 Takeda Chemical Industries, Ltd. Cephem compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids

Also Published As

Publication number Publication date
LU77756A1 (ru) 1978-02-08
GB1561236A (en) 1980-02-13
FR2358411A1 (fr) 1978-02-10
DK143344C (da) 1981-12-14
FI772179A (ru) 1978-01-14
IE45548B1 (en) 1982-09-22
JPS5328191A (en) 1978-03-16
CA1142918A (en) 1983-03-15
SE8205482L (sv) 1982-09-24
SE8205482D0 (sv) 1982-09-24
YU171977A (en) 1982-06-30
NL7707820A (nl) 1978-01-17
AU2698277A (en) 1979-01-18
GR81280B (ru) 1984-12-11
FR2358411B1 (ru) 1981-06-12
SE7708053L (sv) 1978-01-14
IE45548L (en) 1978-01-13
AU511805B2 (en) 1980-09-04
DE2731724A1 (de) 1978-01-19
DK143344B (da) 1981-08-10
BE856785A (fr) 1978-01-13
DK312677A (da) 1978-01-14

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PL Patent ceased