DE2731308A1 - Psychopharmakologisch wirksame peptide und peptidderivate und verfahren zu deren herstellung - Google Patents

Psychopharmakologisch wirksame peptide und peptidderivate und verfahren zu deren herstellung

Info

Publication number
DE2731308A1
DE2731308A1 DE19772731308 DE2731308A DE2731308A1 DE 2731308 A1 DE2731308 A1 DE 2731308A1 DE 19772731308 DE19772731308 DE 19772731308 DE 2731308 A DE2731308 A DE 2731308A DE 2731308 A1 DE2731308 A1 DE 2731308A1
Authority
DE
Germany
Prior art keywords
ala
phe
met
lys
boc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19772731308
Other languages
German (de)
English (en)
Inventor
Hendrik Marie Greven
David De Prof Dr Wied
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Publication of DE2731308A1 publication Critical patent/DE2731308A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/695—Corticotropin [ACTH]
    • C07K14/6955—Corticotropin [ACTH] with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19772731308 1976-07-12 1977-07-11 Psychopharmakologisch wirksame peptide und peptidderivate und verfahren zu deren herstellung Withdrawn DE2731308A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7607684A NL7607684A (nl) 1976-07-12 1976-07-12 Werkwijze ter bereiding van nieuwe peptiden en peptide-derivaten en de toepassing hiervan.

Publications (1)

Publication Number Publication Date
DE2731308A1 true DE2731308A1 (de) 1978-01-19

Family

ID=19826579

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772731308 Withdrawn DE2731308A1 (de) 1976-07-12 1977-07-11 Psychopharmakologisch wirksame peptide und peptidderivate und verfahren zu deren herstellung

Country Status (18)

Country Link
US (1) US4104371A (enExample)
JP (1) JPS5323938A (enExample)
AU (1) AU504317B2 (enExample)
BE (1) BE856696A (enExample)
CA (1) CA1100947A (enExample)
CH (1) CH636598A5 (enExample)
DE (1) DE2731308A1 (enExample)
DK (1) DK149112B (enExample)
ES (1) ES460620A1 (enExample)
FI (1) FI67366C (enExample)
FR (1) FR2358384A1 (enExample)
GB (1) GB1557076A (enExample)
HU (1) HU181843B (enExample)
IE (1) IE45607B1 (enExample)
LU (1) LU77724A1 (enExample)
NL (1) NL7607684A (enExample)
SE (1) SE442205B (enExample)
ZA (1) ZA773951B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2491922A1 (fr) * 1980-10-14 1982-04-16 Roussel Uclaf Nouveaux hexapeptides, procede pour leur preparation et application comme medicaments
NL8101724A (nl) * 1981-04-08 1982-11-01 Akzo Nv Peptiden met zenuw-regenererende eigenschappen.
US4500713A (en) * 1982-09-23 1985-02-19 Usv Pharmaceutical Corporation Therapeutic dipeptides
IE56254B1 (en) * 1982-11-10 1991-06-05 Akzo Nv Peptides
US4623715A (en) * 1984-10-22 1986-11-18 Hoechst Aktiengeselleschaft Novel peptides which are active on the central nervous system and have an action on the cholinergic system
JPS6272254U (enExample) * 1985-10-26 1987-05-08
JPS6272255U (enExample) * 1985-10-26 1987-05-08
GB2217319A (en) * 1988-04-19 1989-10-25 Synpharm Ltd Racemic and optically active fatty amino acids, their homo- abd hetero-oligomers and conjugates, the process of their production, their pharmaceutical composi
IE912091A1 (en) * 1990-07-18 1992-01-29 Akzo Nv Use of a centrally acting atch analog in the manufacture of a¹medicament
US6261794B1 (en) * 1999-10-14 2001-07-17 Saint Louis University Methods for identifying inhibitors of methionine aminopeptidases
US20020182701A1 (en) * 2001-08-30 2002-12-05 Saint Louis University Dominant negative variants of methionine aminopeptidase 2 (MetAP2) and clinical uses thereof
US20130059914A1 (en) 2010-04-21 2013-03-07 Signature Therapeutics, Inc. Compositions Comprising Enzyme-Cleavable Amphetamine Prodrugs and Inhibitors Thereof
MX2024003466A (es) 2021-09-29 2024-06-04 Ensysce Biosciences Inc Profarmacos de metadona escindibles por enzimas y metodos de uso de los mismos.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2315826A1 (de) * 1972-03-31 1973-10-11 Akzo Nv Psychopharmakologisch aktive peptide und peptidderivate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795788A (nl) * 1972-02-22 1973-08-22 Akzo Nv Werkwijze ter bereiding van peptiden en peptide-derivaten en de toepassing hiervan
US3856770A (en) * 1972-03-08 1974-12-24 Akzona Inc Psychopharmacologically active tetra-, penta-, hexa-, and heptapeptides
NL175618C (nl) * 1972-07-15 1984-12-03 Akzo Nv Werkwijze ter bereiding van een farmaceutisch preparaat met psychofarmacologische werking, dat een peptide of peptide-derivaat bevat, alsmede een werkwijze ter bereiding van dergelijke peptiden.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2315826A1 (de) * 1972-03-31 1973-10-11 Akzo Nv Psychopharmakologisch aktive peptide und peptidderivate
DE2315826C2 (de) * 1972-03-31 1983-11-03 Akzo N.V., 6826 Arnhem Peptide und deren Derivate sowie diese Verbindungen enthaltende Arzneimittel mit psychopharmakologischer Wirkung

Also Published As

Publication number Publication date
FI67366B (fi) 1984-11-30
NL7607684A (nl) 1978-01-16
JPS5323938A (en) 1978-03-06
DK314177A (da) 1978-01-13
SE7708036L (sv) 1978-01-13
LU77724A1 (enExample) 1977-10-07
SE442205B (sv) 1985-12-09
FI772156A7 (enExample) 1978-01-13
US4104371A (en) 1978-08-01
HU181843B (en) 1983-11-28
ZA773951B (en) 1978-05-30
GB1557076A (en) 1979-12-05
CH636598A5 (de) 1983-06-15
IE45607B1 (en) 1982-10-06
FR2358384B1 (enExample) 1980-02-01
IE45607L (en) 1978-01-12
FI67366C (fi) 1985-03-11
CA1100947A (en) 1981-05-12
AU504317B2 (en) 1979-10-11
ES460620A1 (es) 1978-05-01
AU2684477A (en) 1979-01-11
DK149112B (da) 1986-01-27
FR2358384A1 (fr) 1978-02-10
BE856696A (fr) 1978-01-11

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8130 Withdrawal