DE2711655C2 - - Google Patents
Info
- Publication number
- DE2711655C2 DE2711655C2 DE2711655A DE2711655A DE2711655C2 DE 2711655 C2 DE2711655 C2 DE 2711655C2 DE 2711655 A DE2711655 A DE 2711655A DE 2711655 A DE2711655 A DE 2711655A DE 2711655 C2 DE2711655 C2 DE 2711655C2
- Authority
- DE
- Germany
- Prior art keywords
- benzyl
- methyl
- furo
- dihydro
- pyridin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C2204/00—Features not otherwise provided for
- A61C2204/002—Features not otherwise provided for using batteries
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Priority Applications (32)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19772760038 DE2760038C2 (US06589383-20030708-C00041.png) | 1977-03-17 | 1977-03-17 | |
DE19772711655 DE2711655A1 (de) | 1977-03-17 | 1977-03-17 | Pyridinyl-aminoalkylaether |
GR55546A GR64096B (en) | 1977-03-17 | 1978-02-25 | Aminoalkylethers of pyridinyl |
GB9334/78A GB1599061A (en) | 1977-03-17 | 1978-03-09 | Pyridinyl aminoalkyl ethers useful for treating cardiac arrhythmias |
US05/885,434 US4206117A (en) | 1977-03-17 | 1978-03-10 | Pyridinyl aminoalkyl ethers |
IT21099/78A IT1093796B (it) | 1977-03-17 | 1978-03-10 | Piridinil-aminoalchileteri |
IE503/78A IE46484B1 (en) | 1977-03-17 | 1978-03-13 | Pyridinyl aminoalkyl ehers useful for treating cardiac arrhythmias |
NLAANVRAGE7802719,A NL189563C (nl) | 1977-03-17 | 1978-03-13 | Pyridyl-aminoalkyl-ethers alsmede farmaceutische preparaten daarvan die werkzaam zijn tegen hartritmestoornissen. |
IL54265A IL54265A0 (en) | 1977-03-17 | 1978-03-13 | New pyrimidinyl aminoalkyl ether derivatives, their manufacture and pharmaceutical compositions containing them |
FR7807262A FR2383930A1 (fr) | 1977-03-17 | 1978-03-14 | Ethers aminoalcoyliques de pyridinyle, leurs procedes d'obtention et preparations pharmaceutiques les contenant |
SE7802927A SE446185B (sv) | 1977-03-17 | 1978-03-14 | Forfarande for framstellning av pyridinylaminoalkyletrar |
CH278478A CH638186A5 (de) | 1977-03-17 | 1978-03-14 | Neue pyridinyl-aminoalkylaether. |
DD78204190A DD134090A5 (de) | 1977-03-17 | 1978-03-15 | Verfahren zur herstellung von pyridinylaminoalkylaether |
BE185950A BE864917A (fr) | 1977-03-17 | 1978-03-15 | Ethers aminoalcoyliques de pyridinyle, procedes pour leur preparation et preparations pharmaceutiques les contenant |
LU79235A LU79235A1 (de) | 1977-03-17 | 1978-03-15 | Verfahren zur herstellung neuer pyridinyl-aminoalkylaethern |
SU782589450A SU799658A3 (ru) | 1977-03-17 | 1978-03-15 | Способ получени солей пири-диНилАМиНОАлКилОВыХ эфиРОВ |
AU34195/78A AU525566B2 (en) | 1977-03-01 | 1978-03-16 | Pyridinyl aminoalkyl ethers |
ES467931A ES467931A1 (es) | 1977-03-17 | 1978-03-16 | Procedimiento para la obtencion de piridinil-aminoalquilete-res |
AT0187878A AT364360B (de) | 1977-03-17 | 1978-03-16 | Verfahren zur herstellung von neuen pyridinyl-aminoalkylaethern und ihrer saeureadditionssalze |
ZA00781552A ZA781552B (en) | 1977-03-17 | 1978-03-16 | Pyridinyl aminoalkyl ethers,their preparation and pharmaceutical formulations thereof |
CS787593A CS202012B2 (en) | 1977-03-17 | 1978-03-16 | Process for preparing new pyridylaminoalkylethers |
CS781680A CS202011B2 (en) | 1977-03-17 | 1978-03-16 | Process for preparing new pyridylaminoalkylethers |
CA299,068A CA1108148A (en) | 1977-03-17 | 1978-03-16 | Pyridinyl aminoalkyl ethers |
HU78BA3641A HU177287B (en) | 1977-03-17 | 1978-03-16 | Process for producing pyrimidyl-aminoalkylether derivatives |
NO780931A NO150605C (no) | 1977-03-17 | 1978-03-16 | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridinyl-aminoalkyletere |
YU00636/78A YU63678A (en) | 1977-03-17 | 1978-03-16 | Process for obtaining new pyridinyl-aminoalkylethers |
DK118578A DK118578A (da) | 1977-03-17 | 1978-03-16 | Fr&mgangsmaade til fremstilling af pyridinylaminoalkylethere,n-oxider eller physiologisk acceptable syreadditionssalte deraf |
FI780842A FI74962C (fi) | 1977-03-17 | 1978-03-17 | Foerfarande foer framstaellning av terapeutiskt anvaendbara 4,5-dikarbalkoxi-6-bensylpyridin-3-yl- - alkylaminoalkyletrar och 4-bensyl-1,3-dihydrofuro/3,4-c/pyridin-7-yl- alkylaminoalkyletrar. |
JP3004178A JPS53116382A (en) | 1977-03-17 | 1978-03-17 | Novel pyridinyllaminoalkyl ether |
SU782699099A SU850002A3 (ru) | 1977-03-17 | 1978-12-19 | Способ получени простых пиридиниламино-АлКилОВыХ эфиРОВ или иХ физиОлОгичЕСКипРиЕМлЕМыХ СОлЕй |
AT0084080A AT364361B (de) | 1977-03-17 | 1980-02-15 | Verfahren zur herstellung von neuen pyridinyl-aminoalkylaethern und ihrer saeureadditionssalze |
YU2252/82A YU41016B (en) | 1977-03-17 | 1982-10-07 | Process for obtaining new pyridinyl aminoalkylethers |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19772711655 DE2711655A1 (de) | 1977-03-17 | 1977-03-17 | Pyridinyl-aminoalkylaether |
Publications (2)
Publication Number | Publication Date |
---|---|
DE2711655A1 DE2711655A1 (de) | 1978-09-21 |
DE2711655C2 true DE2711655C2 (US06589383-20030708-C00041.png) | 1987-07-16 |
Family
ID=6003884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19772711655 Granted DE2711655A1 (de) | 1977-03-01 | 1977-03-17 | Pyridinyl-aminoalkylaether |
Country Status (27)
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4474781A (en) * | 1979-04-02 | 1984-10-02 | Merck & Co., Inc. | Treating hypertension with aminoalkoxypyridines |
DE3008522A1 (de) * | 1980-03-06 | 1981-09-17 | Basf Ag, 6700 Ludwigshafen | 4-(alpha)-cycloamino-arylmethyl-6-methyl-1,3-dihydro-furo (3,4-c) -pyridin-7-ole, ihre herstellung und verwendung |
IL62602A (en) * | 1980-05-19 | 1984-06-29 | Labaz Sanofi Nv | Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them |
JPS588066A (ja) * | 1981-07-03 | 1983-01-18 | Otsuka Pharmaceut Co Ltd | 光学活性〔s〕−(−)−カルボスチリル誘導体の製造法 |
EP0097000B1 (en) * | 1982-06-10 | 1987-09-09 | Beecham Wuelfing GmbH & Co KG | Amine derivatives |
DE3519693A1 (de) * | 1985-06-01 | 1987-01-02 | Basf Ag | Pyridin-derivate, ihre herstellung und verwendung |
GB8603475D0 (en) * | 1986-02-12 | 1986-03-19 | Glaxo Group Ltd | Chemical compounds |
GB8703007D0 (en) * | 1987-02-10 | 1987-03-18 | Glaxo Group Ltd | Chemical compounds |
GB9012926D0 (en) * | 1990-06-09 | 1990-08-01 | Scras | Pyrrolo-pyridine derivatives |
CA2547947C (en) * | 1990-11-30 | 2007-09-25 | Masatoshi Chihiro | Azole derivatives as active superoxide radical inhibitors |
MY128323A (en) | 1996-09-30 | 2007-01-31 | Otsuka Pharma Co Ltd | Thiazole derivatives for inhibition of cytokine production and of cell adhesion |
US20010034357A1 (en) * | 2000-02-02 | 2001-10-25 | Nan-Horng Lin | Substituted pyridine compounds useful for controlling chemical synaptic transmission |
CA2521135A1 (en) * | 2003-04-07 | 2004-10-28 | Kalypsys, Inc. | N-containing heteroaromatic compounds as modulators of ppars and methods of treating metabolic disorders |
PT3135672T (pt) * | 2008-10-10 | 2020-04-02 | Vm Discovery Inc | Composições e métodos para o tratamento distúrbios de utilização de álcool, dor e outras doenças |
KR101698153B1 (ko) * | 2010-04-26 | 2017-01-23 | 광주과학기술원 | P2x1 및 p2x3 수용체 길항제로 사용되는 신규한 피리딘 카르복실산계 화합물, 이의 제조방법 및 이를 포함하는 조성물 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1572768A (en) * | 1925-06-26 | 1926-02-09 | Winthrop Chem Co Inc | Pharmaceutical product |
US1881236A (en) * | 1929-08-10 | 1932-10-04 | Soc Of Chemical Ind | Basic ethers of the pyridine series |
US3535328A (en) * | 1967-09-01 | 1970-10-20 | Exxon Research Engineering Co | Certain substituted aminothioethoxy pyridines |
AR206801A1 (es) * | 1973-02-20 | 1976-08-23 | Ciba Geigy Ag | Procedimiento para la elaboracion de derivados del 1-pirid loxi-2-hidroxi-3-amino-propano |
US4115575A (en) * | 1973-02-20 | 1978-09-19 | Ciba-Geigy Corporation | 2-(3-Amino-2-hydroxy-propoxy)-pyrazines |
US4073909A (en) * | 1973-10-08 | 1978-02-14 | Sandoz Ltd. | Isoquinoline compounds |
CH591448A5 (US06589383-20030708-C00041.png) * | 1974-05-14 | 1977-09-15 | Ciba Geigy Ag | |
CH614711A5 (US06589383-20030708-C00041.png) * | 1975-04-08 | 1979-12-14 | Sandoz Ag | |
GB1504424A (en) * | 1975-08-09 | 1978-03-22 | Beecham Group Ltd | Isoquinoline-derived aminoethers |
GB1485919A (en) | 1975-08-12 | 1977-09-14 | Grindstedvaerket As | Pyridine derivatives |
US4060601A (en) * | 1976-06-15 | 1977-11-29 | Merck & Co., Inc. | Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines |
-
1977
- 1977-03-17 DE DE19772711655 patent/DE2711655A1/de active Granted
-
1978
- 1978-02-25 GR GR55546A patent/GR64096B/el unknown
- 1978-03-09 GB GB9334/78A patent/GB1599061A/en not_active Expired
- 1978-03-10 IT IT21099/78A patent/IT1093796B/it active
- 1978-03-10 US US05/885,434 patent/US4206117A/en not_active Expired - Lifetime
- 1978-03-13 IE IE503/78A patent/IE46484B1/en unknown
- 1978-03-13 NL NLAANVRAGE7802719,A patent/NL189563C/xx not_active IP Right Cessation
- 1978-03-13 IL IL54265A patent/IL54265A0/xx not_active IP Right Cessation
- 1978-03-14 SE SE7802927A patent/SE446185B/sv not_active IP Right Cessation
- 1978-03-14 CH CH278478A patent/CH638186A5/de not_active IP Right Cessation
- 1978-03-14 FR FR7807262A patent/FR2383930A1/fr active Granted
- 1978-03-15 LU LU79235A patent/LU79235A1/de unknown
- 1978-03-15 SU SU782589450A patent/SU799658A3/ru active
- 1978-03-15 DD DD78204190A patent/DD134090A5/xx unknown
- 1978-03-15 BE BE185950A patent/BE864917A/xx not_active IP Right Cessation
- 1978-03-16 ZA ZA00781552A patent/ZA781552B/xx unknown
- 1978-03-16 AT AT0187878A patent/AT364360B/de not_active IP Right Cessation
- 1978-03-16 DK DK118578A patent/DK118578A/da unknown
- 1978-03-16 ES ES467931A patent/ES467931A1/es not_active Expired
- 1978-03-16 YU YU00636/78A patent/YU63678A/xx unknown
- 1978-03-16 CA CA299,068A patent/CA1108148A/en not_active Expired
- 1978-03-16 CS CS781680A patent/CS202011B2/cs unknown
- 1978-03-16 AU AU34195/78A patent/AU525566B2/en not_active Expired
- 1978-03-16 NO NO780931A patent/NO150605C/no unknown
- 1978-03-16 CS CS787593A patent/CS202012B2/cs unknown
- 1978-03-16 HU HU78BA3641A patent/HU177287B/hu not_active IP Right Cessation
- 1978-03-17 JP JP3004178A patent/JPS53116382A/ja active Granted
- 1978-03-17 FI FI780842A patent/FI74962C/fi not_active IP Right Cessation
- 1978-12-19 SU SU782699099A patent/SU850002A3/ru active
-
1980
- 1980-02-15 AT AT0084080A patent/AT364361B/de not_active IP Right Cessation
-
1982
- 1982-10-07 YU YU2252/82A patent/YU41016B/xx unknown
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8330 | Complete renunciation |