DE2626294C3 - Implantierbare Dosiereinrichtung - Google Patents
Implantierbare DosiereinrichtungInfo
- Publication number
- DE2626294C3 DE2626294C3 DE2626294A DE2626294A DE2626294C3 DE 2626294 C3 DE2626294 C3 DE 2626294C3 DE 2626294 A DE2626294 A DE 2626294A DE 2626294 A DE2626294 A DE 2626294A DE 2626294 C3 DE2626294 C3 DE 2626294C3
- Authority
- DE
- Germany
- Prior art keywords
- hydrogen
- electrodes
- dosing device
- space
- ion exchange
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000001257 hydrogen Substances 0.000 claims description 53
- 229910052739 hydrogen Inorganic materials 0.000 claims description 53
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 50
- 239000003814 drug Substances 0.000 claims description 35
- 239000007788 liquid Substances 0.000 claims description 26
- 229940079593 drug Drugs 0.000 claims description 20
- 239000003014 ion exchange membrane Substances 0.000 claims description 18
- 239000010425 asbestos Substances 0.000 claims description 8
- 229910052895 riebeckite Inorganic materials 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 7
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 5
- 241001465754 Metazoa Species 0.000 claims description 5
- 239000008103 glucose Substances 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 5
- 230000005684 electric field Effects 0.000 claims description 4
- 239000012530 fluid Substances 0.000 claims description 4
- 229910052723 transition metal Inorganic materials 0.000 claims description 2
- 150000003623 transition metal compounds Chemical class 0.000 claims description 2
- 150000003624 transition metals Chemical class 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 239000012528 membrane Substances 0.000 description 10
- 239000007789 gas Substances 0.000 description 8
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 230000008859 change Effects 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 238000005370 electroosmosis Methods 0.000 description 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 4
- 229910052782 aluminium Inorganic materials 0.000 description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
- 239000003011 anion exchange membrane Substances 0.000 description 3
- 230000006399 behavior Effects 0.000 description 3
- 238000005341 cation exchange Methods 0.000 description 3
- 230000036571 hydration Effects 0.000 description 3
- 238000006703 hydration reaction Methods 0.000 description 3
- 150000002431 hydrogen Chemical class 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 230000003204 osmotic effect Effects 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 102000004877 Insulin Human genes 0.000 description 2
- 108090001061 Insulin Proteins 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 238000012377 drug delivery Methods 0.000 description 2
- 239000013013 elastic material Substances 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 229910001415 sodium ion Inorganic materials 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 229910021607 Silver chloride Inorganic materials 0.000 description 1
- 229910010340 TiFe Inorganic materials 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 150000001450 anions Chemical class 0.000 description 1
- 239000010953 base metal Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 229910052793 cadmium Inorganic materials 0.000 description 1
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 239000003246 corticosteroid Substances 0.000 description 1
- 229960001334 corticosteroids Drugs 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000009795 derivation Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 238000005868 electrolysis reaction Methods 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hcl hcl Chemical compound Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 150000004678 hydrides Chemical class 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 229910052987 metal hydride Inorganic materials 0.000 description 1
- 150000004681 metal hydrides Chemical class 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229910000510 noble metal Inorganic materials 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- -1 polytetrafluoroethylene Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 229920000260 silastic Polymers 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2626294A DE2626294C3 (de) | 1976-06-11 | 1976-06-11 | Implantierbare Dosiereinrichtung |
| SE7706055A SE7706055L (sv) | 1976-06-11 | 1977-05-24 | Implanterbar doseringsanordning |
| US05/802,969 US4140121A (en) | 1976-06-11 | 1977-06-02 | Implantable dosing device |
| JP6877177A JPS52151720A (en) | 1976-06-11 | 1977-06-10 | Apparatus for preparing and administering plantable medicine |
| FR7717942A FR2354105A1 (fr) | 1976-06-11 | 1977-06-10 | Doseur pouvant etre implante |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2626294A DE2626294C3 (de) | 1976-06-11 | 1976-06-11 | Implantierbare Dosiereinrichtung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE2626294A1 DE2626294A1 (de) | 1977-12-15 |
| DE2626294B2 DE2626294B2 (de) | 1979-05-17 |
| DE2626294C3 true DE2626294C3 (de) | 1980-01-10 |
Family
ID=5980350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2626294A Expired DE2626294C3 (de) | 1976-06-11 | 1976-06-11 | Implantierbare Dosiereinrichtung |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4140121A (OSRAM) |
| JP (1) | JPS52151720A (OSRAM) |
| DE (1) | DE2626294C3 (OSRAM) |
| FR (1) | FR2354105A1 (OSRAM) |
| SE (1) | SE7706055L (OSRAM) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4298002A (en) * | 1979-09-10 | 1981-11-03 | National Patent Development Corporation | Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation |
| US4306553A (en) * | 1980-07-22 | 1981-12-22 | The Regents Of The University Of Minnesota | Method of maintaining the fluidity of hormone solutions for parenteral administration |
| US4364385A (en) * | 1981-03-13 | 1982-12-21 | Lossef Steven V | Insulin delivery device |
| US4639244A (en) * | 1983-05-03 | 1987-01-27 | Nabil I. Rizk | Implantable electrophoretic pump for ionic drugs and associated methods |
| US4585652A (en) * | 1984-11-19 | 1986-04-29 | Regents Of The University Of Minnesota | Electrochemical controlled release drug delivery system |
| US4715850A (en) * | 1984-12-06 | 1987-12-29 | Controlled Release Technologies, Inc. | Therapeutic agent delivery system and method |
| US4842598A (en) * | 1984-12-06 | 1989-06-27 | Controlled Release Technologies, Inc. | Therapeutic agent delivery system and method |
| US4822339A (en) * | 1984-12-06 | 1989-04-18 | Controlled Release Technologies, Inc. | Therapeutic agent delivery system and method |
| GB2175207B (en) * | 1985-05-20 | 1989-07-05 | Nabil Ibraham Rizk | Improvements in or relating to implantable electrophoretic pumps |
| US4820273A (en) * | 1988-03-01 | 1989-04-11 | Eaton Corporation | Implantable medication infusion device and bolus generator therefor |
| US5041107A (en) * | 1989-10-06 | 1991-08-20 | Cardiac Pacemakers, Inc. | Electrically controllable, non-occluding, body implantable drug delivery system |
| ATE168497T1 (de) * | 1993-01-21 | 1998-08-15 | Mayo Foundation | Mikropartikelschaltvorrichtung |
| US5820879A (en) * | 1993-02-12 | 1998-10-13 | Access Pharmaceuticals, Inc. | Method of delivering a lipid-coated condensed-phase microparticle composition |
| US5753261A (en) * | 1993-02-12 | 1998-05-19 | Access Pharmaceuticals, Inc. | Lipid-coated condensed-phase microparticle composition |
| US5654006A (en) * | 1993-02-12 | 1997-08-05 | Mayo Foundation For Medical Education And Research | Condensed-phase microparticle composition and method |
| US5494415A (en) * | 1994-09-12 | 1996-02-27 | Morita; Yoshimitsu | Magnetically-driven pump |
| US5573651A (en) * | 1995-04-17 | 1996-11-12 | The Dow Chemical Company | Apparatus and method for flow injection analysis |
| US6571125B2 (en) * | 2001-02-12 | 2003-05-27 | Medtronic, Inc. | Drug delivery device |
| DE10205373B4 (de) * | 2002-02-09 | 2007-07-19 | Aloys Wobben | Brandschutz |
| US6872292B2 (en) * | 2003-01-28 | 2005-03-29 | Microlin, L.C. | Voltage modulation of advanced electrochemical delivery system |
| US20080102119A1 (en) * | 2006-11-01 | 2008-05-01 | Medtronic, Inc. | Osmotic pump apparatus and associated methods |
| US7718047B2 (en) * | 2004-10-19 | 2010-05-18 | The Regents Of The University Of Colorado | Electrochemical high pressure pump |
| US20060095001A1 (en) * | 2004-10-29 | 2006-05-04 | Transcutaneous Technologies Inc. | Electrode and iontophoresis device |
| WO2006055729A1 (en) * | 2004-11-16 | 2006-05-26 | Transcutaneous Technologies Inc. | Iontophoretic device and method for administering immune response-enhancing agents and compositions |
| JP4728631B2 (ja) * | 2004-11-30 | 2011-07-20 | Ｔｔｉ・エルビュー株式会社 | イオントフォレーシス装置 |
| US7590444B2 (en) * | 2004-12-09 | 2009-09-15 | Tti Ellebeau, Inc. | Iontophoresis device |
| JP4731931B2 (ja) * | 2005-02-03 | 2011-07-27 | Ｔｔｉ・エルビュー株式会社 | イオントフォレーシス装置 |
| JP2006296511A (ja) * | 2005-04-15 | 2006-11-02 | Transcutaneous Technologies Inc | 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ |
| JP2006334164A (ja) * | 2005-06-02 | 2006-12-14 | Transcutaneous Technologies Inc | イオントフォレーシス装置及びその制御方法 |
| JP2006346368A (ja) * | 2005-06-20 | 2006-12-28 | Transcutaneous Technologies Inc | イオントフォレーシス装置及びその製造方法 |
| JP2007000342A (ja) * | 2005-06-23 | 2007-01-11 | Transcutaneous Technologies Inc | 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置 |
| US20070027426A1 (en) * | 2005-06-24 | 2007-02-01 | Transcutaneous Technologies Inc. | Iontophoresis device to deliver active agents to biological interfaces |
| JPWO2007010900A1 (ja) * | 2005-07-15 | 2009-01-29 | Ｔｔｉ・エルビュー株式会社 | 貼付位置表示機能付き経皮吸収用パッチ及びイオントフォレーシス装置 |
| US20070021735A1 (en) * | 2005-07-15 | 2007-01-25 | Sai Bhavaraju | Dual membrane electro-osmotic fluid delivery device |
| US20070021734A1 (en) * | 2005-07-15 | 2007-01-25 | Sai Bhavaraju | Bioelectro-osmotic engine fluid delivery device |
| US8386030B2 (en) * | 2005-08-08 | 2013-02-26 | Tti Ellebeau, Inc. | Iontophoresis device |
| US8295922B2 (en) | 2005-08-08 | 2012-10-23 | Tti Ellebeau, Inc. | Iontophoresis device |
| US20070088332A1 (en) * | 2005-08-22 | 2007-04-19 | Transcutaneous Technologies Inc. | Iontophoresis device |
| JPWO2007023907A1 (ja) * | 2005-08-24 | 2009-02-26 | Ｔｔｉ・エルビュー株式会社 | 冷凍型イオントフォレーシス用電極構造体 |
| US20070048362A1 (en) * | 2005-08-29 | 2007-03-01 | Transcutaneous Technologies Inc. | General purpose electrolyte solution composition for iontophoresis |
| US20100016781A1 (en) * | 2005-08-29 | 2010-01-21 | Mizuo Nakayama | Iontophoresis device selecting drug to be administered on the basis of information form sensor |
| WO2007029611A1 (ja) * | 2005-09-06 | 2007-03-15 | Tti Ellebeau, Inc. | イオントフォレーシス装置 |
| US20070112294A1 (en) * | 2005-09-14 | 2007-05-17 | Transcutaneous Technologies Inc. | Iontophoresis device |
| JPWO2007032446A1 (ja) | 2005-09-15 | 2009-03-19 | Ｔｔｉ・エルビュー株式会社 | ロッド型イオントフォレーシス装置 |
| JPWO2007032423A1 (ja) * | 2005-09-16 | 2009-03-19 | Ｔｔｉ・エルビュー株式会社 | カテーテル型イオントフォレーシス装置 |
| WO2007037324A1 (ja) * | 2005-09-28 | 2007-04-05 | Transcu Ltd. | 乾燥型イオントフォレーシス用電極構造体 |
| WO2007038028A1 (en) * | 2005-09-28 | 2007-04-05 | Tti Ellebeau, Inc. | Iontophoresis apparatus and method to deliver active agents to biological interfaces |
| JPWO2007037158A1 (ja) * | 2005-09-28 | 2009-04-09 | Ｔｔｉ・エルビュー株式会社 | カプセル型薬物放出装置及びカプセル型薬物放出装置システム |
| BRPI0616771A2 (pt) * | 2005-09-30 | 2011-06-28 | Tti Ellebeau Inc | dispositivo de iontoforese para liberar múltiplos agentes ativos para interfaces biológicas |
| JP4902543B2 (ja) * | 2005-09-30 | 2012-03-21 | Ｔｔｉ・エルビュー株式会社 | 形状記憶セパレータを有するイオントフォレーシス用電極構造体およびそれを用いたイオントフォレーシス装置 |
| US20070078445A1 (en) * | 2005-09-30 | 2007-04-05 | Curt Malloy | Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces |
| WO2007038555A1 (en) * | 2005-09-30 | 2007-04-05 | Tti Ellebeau, Inc. | Iontophoretic device and method of delivery of active agents to biological interface |
| US20070135754A1 (en) * | 2005-09-30 | 2007-06-14 | Hidero Akiyama | Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same |
| KR20080066712A (ko) * | 2005-09-30 | 2008-07-16 | 티티아이 엘뷰 가부시키가이샤 | 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법 |
| US20070078376A1 (en) * | 2005-09-30 | 2007-04-05 | Smith Gregory A | Functionalized microneedles transdermal drug delivery systems, devices, and methods |
| US20070232983A1 (en) * | 2005-09-30 | 2007-10-04 | Smith Gregory A | Handheld apparatus to deliver active agents to biological interfaces |
| EP1944057A4 (en) * | 2005-09-30 | 2009-02-18 | Tti Ellebeau Inc | IONTOPHORESIS DEVICE FOR MONITORING THE DOSE AND TIME OF ADMINISTRATION OF A SLEEP-INDUCING AND ANALYTICAL AGENT |
| WO2007041118A1 (en) * | 2005-09-30 | 2007-04-12 | Tti Ellebeau, Inc. | Iontophoretic device and method of delivery of active agents to biological interface |
| US20070093788A1 (en) * | 2005-09-30 | 2007-04-26 | Darrick Carter | Iontophoresis method and apparatus for systemic delivery of active agents |
| US20070197955A1 (en) * | 2005-10-12 | 2007-08-23 | Transcutaneous Technologies Inc. | Mucous membrane adhesion-type iontophoresis device |
| WO2007079116A1 (en) * | 2005-12-28 | 2007-07-12 | Tti Ellebeau, Inc. | Electroosmotic pump apparatus and method to deliver active agents to biological interfaces |
| US20080033398A1 (en) * | 2005-12-29 | 2008-02-07 | Transcutaneous Technologies Inc. | Device and method for enhancing immune response by electrical stimulation |
| WO2007079193A2 (en) * | 2005-12-30 | 2007-07-12 | Tti Ellebeau, Inc. | Iontophoretic systems, devices, and methods of delivery of active agents to biological interface |
| WO2007079189A2 (en) * | 2005-12-30 | 2007-07-12 | Tti Ellebeau, Inc. | System and method for remote based control of an iontophoresis device |
| EP2319558B1 (en) | 2006-03-14 | 2014-05-21 | University Of Southern California | Mems device for delivery of therapeutic agents |
| US20080077076A1 (en) * | 2006-08-29 | 2008-03-27 | Transcutaneous Technologies Inc. | Iontophoresis device and method for operation with a usb (universal serial bus) power source |
| MX2009002321A (es) * | 2006-09-05 | 2009-03-23 | Tti Ellebeau Inc | Sistemas, dispositivos y metodos de suministro transdermico de farmacos que utilizan suministros de energia inductiva. |
| JP5383497B2 (ja) * | 2006-12-01 | 2014-01-08 | Ｔｔｉ・エルビュー株式会社 | 装置、例として経皮送達装置に給電し且つ／又は当該装置を制御するシステム及び装置 |
| MX2009012273A (es) * | 2007-05-18 | 2010-04-09 | Tti Ellebeau Inc | Dispositivos de suministro transd?rmico que aseguran la liberaci?n mejorada de un principio activo a trav?s de una interfaz biol?gica. |
| EP2666510B1 (en) * | 2007-12-20 | 2017-10-18 | University Of Southern California | Apparatus for controlled delivery of therapeutic agents |
| US9333297B2 (en) | 2008-05-08 | 2016-05-10 | Minipumps, Llc | Drug-delivery pump with intelligent control |
| CN102202719B (zh) * | 2008-05-08 | 2014-11-26 | 迷你泵有限责任公司 | 可植入泵和用于可植入泵的插管 |
| US9199035B2 (en) * | 2008-05-08 | 2015-12-01 | Minipumps, Llc. | Drug-delivery pumps with dynamic, adaptive control |
| EP2323716B1 (en) * | 2008-05-08 | 2015-03-04 | MiniPumps, LLC | Drug-delivery pumps |
| RU2011113755A (ru) * | 2008-09-10 | 2012-10-20 | Транску Лтд. (Sg) | Устройство и способ для распределения вязких жидкостей на основе hpc в пористые субстраты, например, непрерывным ленточным способом |
| JP2012529353A (ja) * | 2009-06-09 | 2012-11-22 | Ｔｔｉ・エルビュー株式会社 | 長寿命高容量電極、装置および製造方法 |
| WO2013190537A1 (en) * | 2012-06-18 | 2013-12-27 | Michael Tavger | Method and system for delivering solution into the pores of recipient human skin |
| US10886548B2 (en) | 2014-05-07 | 2021-01-05 | L3 Open Water Power, Inc. | Hydrogen management in electrochemical systems |
| DE102018114869A1 (de) | 2018-06-20 | 2019-12-24 | Deutsches Zentrum für Luft- und Raumfahrt e.V. | Fördereinrichtung, Verfahren zur Förderung einer Nutzsubstanz und Verwendung zur Erzeugung einer Förderkraft in einer Fördereinrichtung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS157213B1 (OSRAM) * | 1971-01-08 | 1974-09-16 | ||
| US4034756A (en) * | 1971-01-13 | 1977-07-12 | Alza Corporation | Osmotically driven fluid dispenser |
| US4003379A (en) * | 1974-04-23 | 1977-01-18 | Ellinwood Jr Everett H | Apparatus and method for implanted self-powered medication dispensing |
| US3987790A (en) * | 1975-10-01 | 1976-10-26 | Alza Corporation | Osmotically driven fluid dispenser |
| US4016880A (en) * | 1976-03-04 | 1977-04-12 | Alza Corporation | Osmotically driven active agent dispenser |
-
1976
- 1976-06-11 DE DE2626294A patent/DE2626294C3/de not_active Expired
-
1977
- 1977-05-24 SE SE7706055A patent/SE7706055L/xx unknown
- 1977-06-02 US US05/802,969 patent/US4140121A/en not_active Expired - Lifetime
- 1977-06-10 JP JP6877177A patent/JPS52151720A/ja active Pending
- 1977-06-10 FR FR7717942A patent/FR2354105A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE2626294B2 (de) | 1979-05-17 |
| SE7706055L (sv) | 1977-12-12 |
| US4140121A (en) | 1979-02-20 |
| JPS52151720A (en) | 1977-12-16 |
| FR2354105B1 (OSRAM) | 1980-03-07 |
| FR2354105A1 (fr) | 1978-01-06 |
| DE2626294A1 (de) | 1977-12-15 |
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| OD | Request for examination | ||
| C3 | Grant after two publication steps (3rd publication) | ||
| 8339 | Ceased/non-payment of the annual fee |