DE2621082C2 - Piperazinderivat, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel - Google Patents
Piperazinderivat, Verfahren zu ihrer Herstellung und diese enthaltende ArzneimittelInfo
- Publication number
- DE2621082C2 DE2621082C2 DE2621082A DE2621082A DE2621082C2 DE 2621082 C2 DE2621082 C2 DE 2621082C2 DE 2621082 A DE2621082 A DE 2621082A DE 2621082 A DE2621082 A DE 2621082A DE 2621082 C2 DE2621082 C2 DE 2621082C2
- Authority
- DE
- Germany
- Prior art keywords
- piperazine
- addition salts
- acid addition
- pharmacologically acceptable
- acceptable acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- BLGXFZZNTVWLAY-SCYLSFHTSA-N yohimbine Chemical compound C1=CC=C2C(CCN3C[C@@H]4CC[C@H](O)[C@@H]([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 BLGXFZZNTVWLAY-SCYLSFHTSA-N 0.000 description 1
- 229960000317 yohimbine Drugs 0.000 description 1
- AADVZSXPNRLYLV-UHFFFAOYSA-N yohimbine carboxylic acid Natural products C1=CC=C2C(CCN3CC4CCC(C(C4CC33)C(O)=O)O)=C3NC2=C1 AADVZSXPNRLYLV-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7514804A FR2310763A1 (fr) | 1975-05-13 | 1975-05-13 | Derives 1,4-disubstitues de la piperazine, leur procede de preparation et leurs applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2621082A1 DE2621082A1 (de) | 1976-11-25 |
| DE2621082C2 true DE2621082C2 (de) | 1986-02-13 |
Family
ID=9155135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2621082A Expired DE2621082C2 (de) | 1975-05-13 | 1976-05-12 | Piperazinderivat, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4096259A (Direct) |
| DE (1) | DE2621082C2 (Direct) |
| ES (5) | ES447900A1 (Direct) |
| FR (1) | FR2310763A1 (Direct) |
| GB (1) | GB1528862A (Direct) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
| GB8320701D0 (en) * | 1983-08-01 | 1983-09-01 | Wellcome Found | Chemotherapeutic agent |
| FR2603583B1 (fr) * | 1986-09-05 | 1988-12-09 | Andre Buzas | Derives de la benzhydryloxyethyl-piperidine, procede d'obtention et compositions pharmaceutiques les contenant |
| US5276035A (en) * | 1990-07-26 | 1994-01-04 | Novo Nordisk A/S | 1,4-disubstituted piperazines |
| DK178490D0 (da) * | 1990-07-26 | 1990-07-26 | Novo Nordisk As | 1,4-disubstituerede piperaziner |
| DK178590D0 (da) * | 1990-07-26 | 1990-07-26 | Novo Nordisk As | 1,4-disubstituerede piperaziner |
| FR2815031A1 (fr) * | 2000-10-11 | 2002-04-12 | Gilles Fillion | Compositions et methodes pour la regulation du systeme nerveux |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2953568A (en) * | 1958-03-03 | 1960-09-20 | Ciba Pharm Prod Inc | Derivatives of piperazine |
| US3205134A (en) * | 1961-11-14 | 1965-09-07 | Colgate Palmolive Co | Antidepressant benzilates of piperazinoalkanols |
| DE1795375A1 (de) | 1968-09-21 | 1972-01-05 | Boehringer Mannheim Gmbh | Basische AEther und Verfahren zur Herstellung derselben |
| FR2073277A1 (en) | 1969-12-17 | 1971-10-01 | Ferlux | 1-phenoxy alkyl-4-hydroxy alkyl piperazine - anti-inflammatories and analgesics |
-
1975
- 1975-05-13 FR FR7514804A patent/FR2310763A1/fr active Granted
-
1976
- 1976-05-07 GB GB18937/76A patent/GB1528862A/en not_active Expired
- 1976-05-10 US US05/684,846 patent/US4096259A/en not_active Expired - Lifetime
- 1976-05-12 DE DE2621082A patent/DE2621082C2/de not_active Expired
- 1976-05-13 ES ES447900A patent/ES447900A1/es not_active Expired
- 1976-05-13 ES ES447899A patent/ES447899A1/es not_active Expired
- 1976-05-13 ES ES447902A patent/ES447902A1/es not_active Expired
- 1976-05-13 ES ES447898A patent/ES447898A1/es not_active Expired
- 1976-05-13 ES ES447901A patent/ES447901A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES447898A1 (es) | 1977-07-16 |
| DE2621082A1 (de) | 1976-11-25 |
| ES447901A1 (es) | 1977-06-16 |
| GB1528862A (en) | 1978-10-18 |
| ES447899A1 (es) | 1977-07-01 |
| US4096259A (en) | 1978-06-20 |
| FR2310763B1 (Direct) | 1978-08-04 |
| FR2310763A1 (fr) | 1976-12-10 |
| ES447902A1 (es) | 1977-06-16 |
| ES447900A1 (es) | 1977-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8181 | Inventor (new situation) |
Free format text: ERFINDER IST ANMELDER |
|
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |