DE2552799A1 - Pseudotrisaccharide und verfahren zu ihrer herstellung - Google Patents

Pseudotrisaccharide und verfahren zu ihrer herstellung

Info

Publication number
DE2552799A1
DE2552799A1 DE19752552799 DE2552799A DE2552799A1 DE 2552799 A1 DE2552799 A1 DE 2552799A1 DE 19752552799 DE19752552799 DE 19752552799 DE 2552799 A DE2552799 A DE 2552799A DE 2552799 A1 DE2552799 A1 DE 2552799A1
Authority
DE
Germany
Prior art keywords
gentamicin
antibiotic
amino
epi
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752552799
Other languages
German (de)
English (en)
Inventor
Peter J L Daniels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD International Holdings GmbH
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/611,289 external-priority patent/US4000261A/en
Priority claimed from US05/611,290 external-priority patent/US4000262A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of DE2552799A1 publication Critical patent/DE2552799A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE19752552799 1974-11-29 1975-11-25 Pseudotrisaccharide und verfahren zu ihrer herstellung Withdrawn DE2552799A1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US52859274A 1974-11-29 1974-11-29
US52859374A 1974-11-29 1974-11-29
US05/611,289 US4000261A (en) 1974-11-29 1975-09-08 5-epi-4,6-di-o-(aminoglycosyl)-2-deoxystreptamines, methods for their manufacture and intermediates useful therein, methods for their use as antibacterial agents and compositions useful therefor
US05/611,290 US4000262A (en) 1974-11-29 1975-09-08 5-epi-amino and 5-epi-azido-4,6-di-o-(aminoglycosyl)-2,5-dideoxystreptamines 1-n-alkyl-5-epi-amino and 1-n-alkyl-5-epi-azido-4,6-di-o-(aminoglycosyl)-2,5-dideoxystreptamines

Publications (1)

Publication Number Publication Date
DE2552799A1 true DE2552799A1 (de) 1976-08-12

Family

ID=27504618

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752552799 Withdrawn DE2552799A1 (de) 1974-11-29 1975-11-25 Pseudotrisaccharide und verfahren zu ihrer herstellung

Country Status (17)

Country Link
JP (1) JPS52244A (OSRAM)
AR (1) AR215848A1 (OSRAM)
CA (1) CA1048020A (OSRAM)
CH (1) CH618986A5 (OSRAM)
DE (1) DE2552799A1 (OSRAM)
DK (1) DK531375A (OSRAM)
ES (1) ES442989A1 (OSRAM)
FI (1) FI753318A7 (OSRAM)
FR (1) FR2292482A1 (OSRAM)
GB (1) GB1528930A (OSRAM)
GR (1) GR58472B (OSRAM)
IE (1) IE43126B1 (OSRAM)
IL (1) IL48558A (OSRAM)
LU (1) LU73887A1 (OSRAM)
NL (1) NL7513737A (OSRAM)
NO (2) NO142080C (OSRAM)
SE (1) SE7513330L (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2832268A1 (de) * 1978-07-22 1980-01-31 Bayer Ag Pseudotrisaccharide
DE2924659A1 (de) * 1979-06-19 1981-01-22 Bayer Ag Pseudotrisaccharide, ihre herstellung und verwendung als arzneimittel
JPWO2005070945A1 (ja) * 2004-01-21 2007-09-06 明治製菓株式会社 メチシリン耐性黄色ブドウ球菌（ｍｒｓａ）に有効な新規アミノグリコシド系抗生物質

Also Published As

Publication number Publication date
LU73887A1 (OSRAM) 1976-09-06
DK531375A (da) 1976-05-30
IE43126L (en) 1976-05-29
NO753969L (OSRAM) 1976-06-01
NO142080B (no) 1980-03-17
IL48558A (en) 1980-07-31
IE43126B1 (en) 1980-12-31
CH618986A5 (en) 1980-08-29
NO790908L (no) 1976-06-01
SE7513330L (sv) 1976-05-31
AR215848A1 (es) 1979-11-15
NL7513737A (nl) 1976-06-01
CA1048020A (en) 1979-02-06
GR58472B (en) 1977-10-14
NO142080C (no) 1980-06-25
AU8698875A (en) 1977-06-09
FR2292482A1 (fr) 1976-06-25
GB1528930A (en) 1978-10-18
JPS52244A (en) 1977-01-05
IL48558A0 (en) 1976-01-30
FR2292482B1 (OSRAM) 1981-12-31
ES442989A1 (es) 1977-08-16
FI753318A7 (OSRAM) 1976-05-30

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8139 Disposal/non-payment of the annual fee