DE2515770C2 - Prostaglandinanaloge, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel - Google Patents
Prostaglandinanaloge, Verfahren zu ihrer Herstellung und sie enthaltende ArzneimittelInfo
- Publication number
- DE2515770C2 DE2515770C2 DE2515770A DE2515770A DE2515770C2 DE 2515770 C2 DE2515770 C2 DE 2515770C2 DE 2515770 A DE2515770 A DE 2515770A DE 2515770 A DE2515770 A DE 2515770A DE 2515770 C2 DE2515770 C2 DE 2515770C2
- Authority
- DE
- Germany
- Prior art keywords
- formula
- group
- trans
- compounds
- prostaglandin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- 231100000252 nontoxic Toxicity 0.000 claims description 15
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4018—Esters of cycloaliphatic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB16241/74A GB1488141A (en) | 1974-04-11 | 1974-04-11 | Prostaglandin analogues |
| GB4853574 | 1974-11-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2515770A1 DE2515770A1 (de) | 1975-10-23 |
| DE2515770C2 true DE2515770C2 (de) | 1983-12-08 |
Family
ID=26251917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2515770A Expired DE2515770C2 (de) | 1974-04-11 | 1975-04-10 | Prostaglandinanaloge, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
Country Status (8)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4087620A (en) * | 1975-07-17 | 1978-05-02 | Ono Pharmaceutical Company | 15-Cycloalkyl-prostaglandin derivatives |
| US4180675A (en) * | 1975-07-17 | 1979-12-25 | Warner-Lambert Company | 15-Cycloalkyl-prostaglandin derivatives |
| US4022912A (en) * | 1976-02-09 | 1977-05-10 | Miles Laboratories, Inc. | Use of 1-decarboxy-1-hydroxymethyl-PGE1 in therapeutic bronchodilation |
| US4197407A (en) * | 1977-03-30 | 1980-04-08 | American Cyanamid Company | Prostenoic acids and esters |
| JPS6022710B2 (ja) * | 1977-09-16 | 1985-06-03 | 小野薬品工業株式会社 | プロスタグランジン類似化合物 |
| JPS6033429B2 (ja) * | 1980-04-28 | 1985-08-02 | 小野薬品工業株式会社 | プロスタグランジン類似化合物 |
| HU229547B1 (en) | 1999-10-15 | 2014-01-28 | Sucampo Ag | Novel composition and method for stabilizing the same |
| US6414016B1 (en) | 2000-09-05 | 2002-07-02 | Sucampo, A.G. | Anti-constipation composition |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3849474A (en) * | 1972-03-27 | 1974-11-19 | Ayerst Mckenna & Harrison | 11-deoxyprostaglandin derivatives and process therefor |
-
1975
- 1975-04-08 US US05/566,147 patent/US4034003A/en not_active Expired - Lifetime
- 1975-04-09 FR FR7511036A patent/FR2267097B1/fr not_active Expired
- 1975-04-10 LU LU72257A patent/LU72257A1/xx unknown
- 1975-04-10 DK DK154775A patent/DK154775A/da not_active IP Right Cessation
- 1975-04-10 AU AU80037/75A patent/AU8003775A/en not_active Expired
- 1975-04-10 DE DE2515770A patent/DE2515770C2/de not_active Expired
- 1975-04-10 NL NL7504302A patent/NL7504302A/xx unknown
- 1975-04-10 SE SE7504151A patent/SE7504151L/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK154775A (US07321065-20080122-C00020.png) | 1975-10-12 |
| SE7504151L (sv) | 1975-10-13 |
| DE2515770A1 (de) | 1975-10-23 |
| NL7504302A (nl) | 1975-10-14 |
| US4034003A (en) | 1977-07-05 |
| AU8003775A (en) | 1976-10-14 |
| FR2267097A1 (US07321065-20080122-C00020.png) | 1975-11-07 |
| FR2267097B1 (US07321065-20080122-C00020.png) | 1978-09-08 |
| LU72257A1 (US07321065-20080122-C00020.png) | 1976-03-17 |
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Representative=s name: HENKEL, G., DR.PHIL. FEILER, L., DR.RER.NAT. HAENZ |
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| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |