DE2434693A1 - 1,4-disubstituierte piperidine - Google Patents

1,4-disubstituierte piperidine

Info

Publication number
DE2434693A1
DE2434693A1 DE2434693A DE2434693A DE2434693A1 DE 2434693 A1 DE2434693 A1 DE 2434693A1 DE 2434693 A DE2434693 A DE 2434693A DE 2434693 A DE2434693 A DE 2434693A DE 2434693 A1 DE2434693 A1 DE 2434693A1
Authority
DE
Germany
Prior art keywords
piperidine
fluorophenyl
hydroxy
fluorobenzyl
dioxolane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE2434693A
Other languages
German (de)
English (en)
Inventor
Jun Robert Frederick Boswell
Jun Robert Louis Duncan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of DE2434693A1 publication Critical patent/DE2434693A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2434693A 1973-07-19 1974-07-18 1,4-disubstituierte piperidine Pending DE2434693A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38056873A 1973-07-19 1973-07-19
US48546974A 1974-07-03 1974-07-03

Publications (1)

Publication Number Publication Date
DE2434693A1 true DE2434693A1 (de) 1975-02-06

Family

ID=27009046

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2434693A Pending DE2434693A1 (de) 1973-07-19 1974-07-18 1,4-disubstituierte piperidine

Country Status (9)

Country Link
JP (1) JPS5113779A (US07709020-20100504-C00041.png)
CA (1) CA1040635A (US07709020-20100504-C00041.png)
DE (1) DE2434693A1 (US07709020-20100504-C00041.png)
ES (2) ES428375A1 (US07709020-20100504-C00041.png)
FR (1) FR2237633B1 (US07709020-20100504-C00041.png)
GB (1) GB1469664A (US07709020-20100504-C00041.png)
NL (1) NL7409752A (US07709020-20100504-C00041.png)
NO (1) NO742621L (US07709020-20100504-C00041.png)
SE (1) SE7409245L (US07709020-20100504-C00041.png)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3002292A1 (de) * 1979-02-09 1980-08-21 Richardson Merrell Inc 4-(naphthylmethyl)piperidin-derivate, verfahren zu deren herstellung und deren verwendung
DE3031892A1 (de) * 1979-09-04 1981-03-19 Richardson-Merrell Inc., Wilton, Conn. Antipsychotisch wirksame cinnamoylpiperidinobutyrophenon-derivate
DE3039974A1 (de) * 1979-10-27 1981-05-07 Richardson-Merrell Inc., Wilton, Conn. Antipsychotisch wirksame 4-(4-alkyl-4-aroyl-1-piperidino)-butyrophenone
EP0208235A1 (en) * 1985-07-02 1987-01-14 Merrell Dow Pharmaceuticals Inc. N-Aralkyl piperidinemethanol derivatives

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE49998B1 (en) * 1979-08-06 1986-01-22 Merrell Dow Pharma 4-(naphthalenyloxy)piperidine derivatives
US4283404A (en) * 1979-09-04 1981-08-11 Richardson-Merrell Inc. Aroylethenylpiperidinobutyrophenone antipsychotic agents
US4783471A (en) * 1985-07-02 1988-11-08 Merrell Dow Pharmaceuticals Inc. N-aralkyl piperidine methanol derivatives and the uses thereof
ES2066721B1 (es) * 1993-05-18 1996-02-16 Ferrer Int Nuevos compuestos derivados de la piridina 1,4-disustituida.
WO2004060865A2 (en) * 2002-12-18 2004-07-22 Fmc Corporation N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3576810A (en) * 1968-06-20 1971-04-27 Robins Co Inc A H 1-substituted-3-(-4)-aroylpiperidines
ZA717147B (en) * 1970-11-27 1972-07-26 Richardson Merrell Inc 4-(4-(alpha-hydroxybenzyl)piperidino)-4'-fluorobutyrophenone derivatives

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3002292A1 (de) * 1979-02-09 1980-08-21 Richardson Merrell Inc 4-(naphthylmethyl)piperidin-derivate, verfahren zu deren herstellung und deren verwendung
DE3031892A1 (de) * 1979-09-04 1981-03-19 Richardson-Merrell Inc., Wilton, Conn. Antipsychotisch wirksame cinnamoylpiperidinobutyrophenon-derivate
DE3039974A1 (de) * 1979-10-27 1981-05-07 Richardson-Merrell Inc., Wilton, Conn. Antipsychotisch wirksame 4-(4-alkyl-4-aroyl-1-piperidino)-butyrophenone
EP0208235A1 (en) * 1985-07-02 1987-01-14 Merrell Dow Pharmaceuticals Inc. N-Aralkyl piperidinemethanol derivatives

Also Published As

Publication number Publication date
ES447895A1 (es) 1977-07-16
SE7409245L (US07709020-20100504-C00041.png) 1975-01-20
CA1040635A (en) 1978-10-17
GB1469664A (en) 1977-04-06
NO742621L (US07709020-20100504-C00041.png) 1975-02-17
FR2237633B1 (US07709020-20100504-C00041.png) 1978-07-21
ES428375A1 (es) 1976-10-01
NL7409752A (nl) 1975-01-21
JPS5113779A (en) 1976-02-03
AU7139374A (en) 1976-01-22
FR2237633A1 (US07709020-20100504-C00041.png) 1975-02-14

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