DE2428792A1 - Neue antiarrhythmika - Google Patents

Neue antiarrhythmika

Info

Publication number
DE2428792A1
DE2428792A1 DE2428792A DE2428792A DE2428792A1 DE 2428792 A1 DE2428792 A1 DE 2428792A1 DE 2428792 A DE2428792 A DE 2428792A DE 2428792 A DE2428792 A DE 2428792A DE 2428792 A1 DE2428792 A1 DE 2428792A1
Authority
DE
Germany
Prior art keywords
bispidine
bispidone
methyl
phenylethyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE2428792A
Other languages
German (de)
English (en)
Inventor
Fritz Dr Binnig
Manfred Dr Rer Nat Raschack
Hans Joerg Dr Rer Nat Treiber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll GmbH filed Critical Knoll GmbH
Priority to DE2428792A priority Critical patent/DE2428792A1/de
Priority to GB2137975A priority patent/GB1445967A/en
Priority to FR7516828A priority patent/FR2274300A1/fr
Priority to US05/585,606 priority patent/US3962449A/en
Priority to NL7506886A priority patent/NL7506886A/xx
Priority to FI751726A priority patent/FI57759C/fi
Priority to BE157260A priority patent/BE830153A/xx
Priority to AT451475A priority patent/AT343660B/de
Priority to SE7506743A priority patent/SE420727B/xx
Priority to CH771275A priority patent/CH618168A5/de
Priority to CA229,274A priority patent/CA1058181A/en
Priority to JP50071827A priority patent/JPS5111791A/ja
Publication of DE2428792A1 publication Critical patent/DE2428792A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE2428792A 1974-06-14 1974-06-14 Neue antiarrhythmika Withdrawn DE2428792A1 (de)

Priority Applications (12)

Application Number Priority Date Filing Date Title
DE2428792A DE2428792A1 (de) 1974-06-14 1974-06-14 Neue antiarrhythmika
GB2137975A GB1445967A (en) 1974-06-14 1975-05-20 Bispidine and bispidone derivatives
FR7516828A FR2274300A1 (fr) 1974-06-14 1975-05-29 Antiarrhythmiques nouveaux
US05/585,606 US3962449A (en) 1974-06-14 1975-06-10 Cardioactive bispidones and bispidines
NL7506886A NL7506886A (nl) 1974-06-14 1975-06-10 Antiarritmica.
FI751726A FI57759C (fi) 1974-06-14 1975-06-10 Foerfarande foer framstaellning av terapeutiskt anvaendbara n,n'-substituerade bispidinderivat
BE157260A BE830153A (fr) 1974-06-14 1975-06-12 Composes antiarythmiques
AT451475A AT343660B (de) 1974-06-14 1975-06-12 Verfahren zur herstellung von neuen bispidinderivaten und ihren salzen
SE7506743A SE420727B (sv) 1974-06-14 1975-06-12 Analogiforfarande for framstellning av bispidin- och bispidonderivat
CH771275A CH618168A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-06-14 1975-06-13
CA229,274A CA1058181A (en) 1974-06-14 1975-06-13 Bispidine compounds
JP50071827A JPS5111791A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-06-14 1975-06-13

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2428792A DE2428792A1 (de) 1974-06-14 1974-06-14 Neue antiarrhythmika

Publications (1)

Publication Number Publication Date
DE2428792A1 true DE2428792A1 (de) 1976-01-02

Family

ID=5918151

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2428792A Withdrawn DE2428792A1 (de) 1974-06-14 1974-06-14 Neue antiarrhythmika

Country Status (12)

Country Link
US (1) US3962449A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5111791A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT343660B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE830153A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1058181A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH618168A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2428792A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI57759C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2274300A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1445967A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7506886A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE420727B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0062199A1 (de) * 1981-03-27 1982-10-13 BASF Aktiengesellschaft N-(4-Aminobenzoyl)-N'-benzylbispidin, seine Herstellung und dieses enthaltende Arzneimittel
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
DE3730224A1 (de) * 1987-09-09 1989-03-23 Kali Chemie Pharma Gmbh 3-cinnamyl-3,7-diazabicyclo(3,3,1) nonan-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0301245A3 (en) * 1987-07-04 1989-05-24 Kali-Chemie Pharma Gmbh 3-sulfonyl-3,7-diazabicyclo-(3,3,1)nonane compounds, processes for their preparation, and medicaments containing these compounds
EP0306871A3 (en) * 1987-09-09 1990-08-01 Kali-Chemie Pharma Gmbh 3,7-diazabicyclo û3,3,1¨ nonane compounds, process for their preparation and medicaments containing them
WO1995002599A1 (de) * 1993-07-17 1995-01-26 Basf Aktiengesellschaft Verfahren zur herstellung von n,n'-dibenzylbispidin
WO2005037052A3 (en) * 2003-10-20 2005-07-07 Astrazeneca Ab Binding assay with labelled bispidine variant

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2726571A1 (de) * 1977-06-13 1978-12-21 Basf Ag Neue bispidinderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten
HU184960B (en) * 1981-07-20 1984-11-28 Richter Gedeon Vegyeszet Process for preparing new derivatives of 3,7-diazabicyclo/3.3.1/ nonane
DE4019080A1 (de) * 1990-06-15 1991-12-19 Kali Chemie Pharma Gmbh Neue 3,7-diazabicycolo (3,3,1)nonan-verbindungen enthaltende arzneimittel
SE9704709D0 (sv) 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
US20040229900A1 (en) * 1999-06-16 2004-11-18 Astrazeneca Ab Bispidine compounds useful in the treatment of cardiac arrythmias
SE9902270D0 (sv) 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
US20050004113A1 (en) * 1999-06-16 2005-01-06 Astrazeneca Ab New bispidine compounds useful in the treatment of cardiac arrhythmias
US7038054B1 (en) * 1999-09-03 2006-05-02 Pharmacopeia Drug Discovery, Inc. Diazabicyclononane scaffold for combinatorial synthesis
SE9904765D0 (sv) 1999-12-23 1999-12-23 Astra Ab Pharmaceutically-useful compounds
SE0002603D0 (sv) * 2000-07-07 2000-07-07 Astrazeneca Ab New compounds
US6808924B1 (en) 2000-07-11 2004-10-26 Claudia Lanari Mouse mammary tumor lines expressing estrogen and progesterone receptors
AR030756A1 (es) * 2000-10-02 2003-09-03 Astrazeneca Ab Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas
SE0003795D0 (sv) * 2000-10-20 2000-10-20 Astrazeneca Ab Pharmaceutically useful compounds
SE0100326D0 (sv) * 2001-02-02 2001-02-02 Astrazeneca Ab New compounds
SE0401539D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
SE0401540D0 (sv) * 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
KR20080021114A (ko) * 2005-06-13 2008-03-06 아스트라제네카 아베 심부정맥의 치료를 위한 신규한 옥사비스피딘 화합물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL124628C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1963-02-05

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0062199A1 (de) * 1981-03-27 1982-10-13 BASF Aktiengesellschaft N-(4-Aminobenzoyl)-N'-benzylbispidin, seine Herstellung und dieses enthaltende Arzneimittel
US4459301A (en) * 1981-03-27 1984-07-10 Basf Aktiengesellschaft Method of treating cardiac disorders using bispidine derivatives
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
US4550112A (en) * 1982-09-18 1985-10-29 Kali-Chemie Pharma Gmbh 3,7-Diazabicyclo(3,3,1)nonane compounds and their use in treating heart disease
EP0301245A3 (en) * 1987-07-04 1989-05-24 Kali-Chemie Pharma Gmbh 3-sulfonyl-3,7-diazabicyclo-(3,3,1)nonane compounds, processes for their preparation, and medicaments containing these compounds
US4906640A (en) * 1987-07-04 1990-03-06 Kali-Chemie Pharma Gmbh 3-sulfonyl-3,7-diazabicyclo[3,3,1]nonane compounds and medicaments containing said compounds
DE3730224A1 (de) * 1987-09-09 1989-03-23 Kali Chemie Pharma Gmbh 3-cinnamyl-3,7-diazabicyclo(3,3,1) nonan-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0306871A3 (en) * 1987-09-09 1990-08-01 Kali-Chemie Pharma Gmbh 3,7-diazabicyclo û3,3,1¨ nonane compounds, process for their preparation and medicaments containing them
WO1995002599A1 (de) * 1993-07-17 1995-01-26 Basf Aktiengesellschaft Verfahren zur herstellung von n,n'-dibenzylbispidin
WO2005037052A3 (en) * 2003-10-20 2005-07-07 Astrazeneca Ab Binding assay with labelled bispidine variant

Also Published As

Publication number Publication date
US3962449A (en) 1976-06-08
ATA451475A (de) 1977-10-15
FI57759B (fi) 1980-06-30
FI751726A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-12-15
FI57759C (fi) 1980-10-10
BE830153A (fr) 1975-12-12
GB1445967A (en) 1976-08-11
SE420727B (sv) 1981-10-26
FR2274300A1 (fr) 1976-01-09
NL7506886A (nl) 1975-12-16
CA1058181A (en) 1979-07-10
FR2274300B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1978-11-10
CH618168A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-07-15
JPS5111791A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-01-30
AT343660B (de) 1978-06-12
SE7506743L (sv) 1975-12-15

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Legal Events

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