DE2413610A1 - Neue heterocyclische verbindungen und verfahren zu deren herstellung - Google Patents
Neue heterocyclische verbindungen und verfahren zu deren herstellungInfo
- Publication number
- DE2413610A1 DE2413610A1 DE2413610A DE2413610A DE2413610A1 DE 2413610 A1 DE2413610 A1 DE 2413610A1 DE 2413610 A DE2413610 A DE 2413610A DE 2413610 A DE2413610 A DE 2413610A DE 2413610 A1 DE2413610 A1 DE 2413610A1
- Authority
- DE
- Germany
- Prior art keywords
- formula
- compounds
- group
- hydrogen
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 150000002391 heterocyclic compounds Chemical class 0.000 title description 2
- 150000001875 compounds Chemical class 0.000 claims description 74
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- 239000001257 hydrogen Substances 0.000 claims description 34
- 125000004432 carbon atom Chemical group C* 0.000 claims description 30
- 125000000217 alkyl group Chemical group 0.000 claims description 24
- 150000002431 hydrogen Chemical class 0.000 claims description 21
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims description 15
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- 229910052736 halogen Inorganic materials 0.000 claims description 12
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- 125000001424 substituent group Chemical group 0.000 claims description 12
- 125000003545 alkoxy group Chemical group 0.000 claims description 9
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- 239000002184 metal Substances 0.000 claims description 7
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims description 6
- 150000001412 amines Chemical class 0.000 claims description 5
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims description 5
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 4
- 230000000737 periodic effect Effects 0.000 claims description 4
- 125000004390 alkyl sulfonyl group Chemical group 0.000 claims description 3
- 125000004472 dialkylaminosulfonyl group Chemical group 0.000 claims description 3
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- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 description 1
- CYQAYERJWZKYML-UHFFFAOYSA-N phosphorus pentasulfide Chemical compound S1P(S2)(=S)SP3(=S)SP1(=S)SP2(=S)S3 CYQAYERJWZKYML-UHFFFAOYSA-N 0.000 description 1
- LPNYRYFBWFDTMA-UHFFFAOYSA-N potassium tert-butoxide Chemical compound [K+].CC(C)(C)[O-] LPNYRYFBWFDTMA-UHFFFAOYSA-N 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 125000001325 propanoyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 201000003004 ptosis Diseases 0.000 description 1
- 150000003254 radicals Chemical group 0.000 description 1
- 238000005932 reductive alkylation reaction Methods 0.000 description 1
- 238000006798 ring closing metathesis reaction Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000007916 tablet composition Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 150000003571 thiolactams Chemical class 0.000 description 1
- XJDNKRIXUMDJCW-UHFFFAOYSA-J titanium tetrachloride Chemical compound Cl[Ti](Cl)(Cl)Cl XJDNKRIXUMDJCW-UHFFFAOYSA-J 0.000 description 1
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH425973 | 1973-03-23 | ||
| CH514773 | 1973-04-10 | ||
| CH664473 | 1973-05-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2413610A1 true DE2413610A1 (de) | 1974-10-10 |
Family
ID=27174779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2413610A Pending DE2413610A1 (de) | 1973-03-23 | 1974-03-21 | Neue heterocyclische verbindungen und verfahren zu deren herstellung |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS49126691A (enrdf_load_stackoverflow) |
| AU (1) | AU6704374A (enrdf_load_stackoverflow) |
| DD (1) | DD110498A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2413610A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2222102A1 (enrdf_load_stackoverflow) |
| IL (1) | IL44458A0 (enrdf_load_stackoverflow) |
| NL (1) | NL7403657A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7491715B2 (en) | 2003-12-22 | 2009-02-17 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US12403143B2 (en) * | 2016-03-04 | 2025-09-02 | Obschestvo S Ogranichennoi Otvetstvennostyu “Valentek” | Pharmaceutical composition for treating functional psychiatric disorders |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4097597A (en) * | 1977-02-23 | 1978-06-27 | Abbott Laboratories | Dibenzo b,e! 1,4!diazepines |
| FI803908A7 (fi) * | 1979-12-21 | 1981-06-22 | Sandoz Ag | Uusia pyrrolobentsotriatsepiineja, niiden valmistus ja niitä sisältävät farmaseuttiset koostumukset. |
| US4431589A (en) * | 1980-12-11 | 1984-02-14 | Lilly House | Benzodiazepine compounds and their use as pharmaceuticals |
| BE1004596A4 (fr) * | 1990-09-26 | 1992-12-22 | Therabel Res S A N V | Derives de methylpiperazinoazepine, leur preparation et leur utilisation. |
| US5393752A (en) * | 1992-05-26 | 1995-02-28 | Therabel Research S.A./N.V. | Methylpiperazinoazepine compounds, preparation and use thereof |
| KR20050106465A (ko) * | 2003-02-27 | 2005-11-09 | 아보트 러보러터리즈 | 헤테로사이클릭 키나제 억제제 |
| WO2008021463A2 (en) * | 2006-08-15 | 2008-02-21 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| RU2667954C2 (ru) * | 2016-03-04 | 2018-09-25 | Общество С Ограниченной Ответственностью "Валентек" | Фармацевтическая композиция для лечения функциональных психических расстройств |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
| CH569731A5 (enrdf_load_stackoverflow) * | 1972-04-04 | 1975-11-28 | Wander Ag Dr A |
-
1974
- 1974-03-19 NL NL7403657A patent/NL7403657A/xx unknown
- 1974-03-21 DE DE2413610A patent/DE2413610A1/de active Pending
- 1974-03-21 DD DD177349A patent/DD110498A5/xx unknown
- 1974-03-21 IL IL44458A patent/IL44458A0/xx unknown
- 1974-03-22 JP JP49031612A patent/JPS49126691A/ja active Pending
- 1974-03-22 AU AU67043/74A patent/AU6704374A/en not_active Expired
- 1974-03-25 FR FR7410147A patent/FR2222102A1/fr active Granted
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7491715B2 (en) | 2003-12-22 | 2009-02-17 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US7517871B2 (en) | 2003-12-22 | 2009-04-14 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US7550454B2 (en) | 2003-12-22 | 2009-06-23 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US7622461B2 (en) | 2003-12-22 | 2009-11-24 | Acadia Pharmaceuticals Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| US12403143B2 (en) * | 2016-03-04 | 2025-09-02 | Obschestvo S Ogranichennoi Otvetstvennostyu “Valentek” | Pharmaceutical composition for treating functional psychiatric disorders |
Also Published As
| Publication number | Publication date |
|---|---|
| AU6704374A (en) | 1975-09-25 |
| NL7403657A (enrdf_load_stackoverflow) | 1974-09-25 |
| FR2222102B1 (enrdf_load_stackoverflow) | 1978-01-06 |
| IL44458A0 (en) | 1974-06-30 |
| DD110498A5 (enrdf_load_stackoverflow) | 1974-12-20 |
| JPS49126691A (enrdf_load_stackoverflow) | 1974-12-04 |
| FR2222102A1 (en) | 1974-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHJ | Non-payment of the annual fee |