DE2364192A1 - Verfahren zur herstellung antibakterieller mittel - Google Patents

Verfahren zur herstellung antibakterieller mittel

Info

Publication number
DE2364192A1
DE2364192A1 DE2364192A DE2364192A DE2364192A1 DE 2364192 A1 DE2364192 A1 DE 2364192A1 DE 2364192 A DE2364192 A DE 2364192A DE 2364192 A DE2364192 A DE 2364192A DE 2364192 A1 DE2364192 A1 DE 2364192A1
Authority
DE
Germany
Prior art keywords
salt
hydroxyphenyl
formula
compound
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE2364192A
Other languages
German (de)
English (en)
Inventor
Jun Leonard Bruce Crast
David Willner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DE2364192A1 publication Critical patent/DE2364192A1/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/061,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2364192A 1972-12-26 1973-12-21 Verfahren zur herstellung antibakterieller mittel Pending DE2364192A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31834072A 1972-12-26 1972-12-26

Publications (1)

Publication Number Publication Date
DE2364192A1 true DE2364192A1 (de) 1974-06-27

Family

ID=23237764

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2364192A Pending DE2364192A1 (de) 1972-12-26 1973-12-21 Verfahren zur herstellung antibakterieller mittel

Country Status (23)

Country Link
JP (4) JPS5652024B2 (xx)
KR (1) KR780000197B1 (xx)
AR (4) AR203636A1 (xx)
AT (1) AT331397B (xx)
BE (1) BE808924A (xx)
BG (3) BG21234A3 (xx)
CH (1) CH602760A5 (xx)
DD (2) DD110664A5 (xx)
DE (1) DE2364192A1 (xx)
ES (3) ES421707A1 (xx)
FR (2) FR2211216B1 (xx)
GB (3) GB1460915A (xx)
HU (2) HU169451B (xx)
IL (3) IL50774A (xx)
IN (1) IN139259B (xx)
LU (1) LU69080A1 (xx)
NL (1) NL7317715A (xx)
NO (1) NO142710C (xx)
OA (1) OA04655A (xx)
RO (1) RO66051A (xx)
SE (2) SE7512971L (xx)
SU (1) SU576948A3 (xx)
ZA (1) ZA739607B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907667A (en) * 1973-08-22 1975-09-23 Gulf Research Development Co Process for producing a lubricating oil from a residue feed
NZ179268A (en) * 1974-12-13 1978-04-28 Bristol Myers Co Derivative of cephalosporin c, the preparation of certain cephalosporins
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
EP0018546B1 (en) * 1979-04-25 1983-09-28 BIOCHEMIE Gesellschaft m.b.H. Process for the production of phenylglycyl chloride hydrochlorides
ATA308979A (de) * 1979-04-25 1982-01-15 Biochemie Gmbh Verfahren zur herstellung von (d)-phenylglycylchlorid hydrochloryd-derivaten
JPS6128429A (ja) * 1983-10-21 1986-02-08 Kazuo Ogata 均質機の分割式均質装置
IT1186778B (it) * 1985-10-15 1987-12-16 Lark Spa Cefatrizina glicerolo solvato cristallino e procedimento per la sua preparazione
JPH01152718U (xx) * 1988-04-13 1989-10-20
CN103772414B (zh) * 2013-12-31 2016-03-09 福建省福抗药业股份有限公司 一种制备丙二醇头孢曲嗪的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1159449B (de) * 1961-03-22 1963-12-19 Gruenenthal Chemie Verfahren zur Herstellung von 6-Acylaminopenicillansaeuren und deren Salzen
IL38099A (en) * 1970-12-17 1976-01-30 Smith Kline French Lab 3-heterocyclyl thiomethylcephalosporins
IE36346B1 (en) * 1971-05-11 1976-10-13 R & L Molecular Research Ltd Antibacterial agents and a process for the preparation thereof
CA1076560A (en) * 1972-06-14 1980-04-29 Smith Kline And French Canada Ltd. 3-heterocyclic thiomethylcephalosporins

Also Published As

Publication number Publication date
FR2211216B1 (xx) 1977-04-22
FR2267307B1 (xx) 1978-05-19
FR2211216A1 (xx) 1974-07-19
BG21234A3 (bg) 1976-03-20
AR205561A1 (es) 1976-05-14
IL50774A (en) 1977-08-31
ES444926A1 (es) 1977-11-16
HU169451B (xx) 1976-11-28
IL43913A0 (en) 1974-03-14
HU167560B (xx) 1975-11-28
NL7317715A (xx) 1974-06-28
NO743649L (no) 1974-06-27
JPS5912661B2 (ja) 1984-03-24
JPS5191283A (en) 1976-08-10
CH602760A5 (xx) 1978-07-31
JPS5652024B2 (xx) 1981-12-09
ATA1083073A (de) 1975-11-15
JPS5953277B2 (ja) 1984-12-24
RO66051A (fr) 1979-08-15
DD110664A5 (xx) 1975-01-05
FR2267307A1 (xx) 1975-11-07
BG21233A3 (bg) 1976-03-20
BE808924A (fr) 1974-06-20
IL50774A0 (en) 1976-12-31
ES421707A1 (es) 1976-09-16
ZA739607B (en) 1974-09-25
SE404692B (sv) 1978-10-23
NO142710C (no) 1980-10-01
JPS5191282A (en) 1976-08-10
LU69080A1 (xx) 1974-08-19
SE7512972L (sv) 1975-11-18
OA04655A (fr) 1980-12-31
AT331397B (de) 1976-08-25
GB1460914A (en) 1977-01-06
ES444927A1 (es) 1977-04-16
NO142710B (no) 1980-06-23
SE7512971L (sv) 1975-11-18
JPS4994696A (xx) 1974-09-09
IL43913A (en) 1977-08-31
KR780000197B1 (en) 1978-05-26
BG21601A3 (bg) 1976-07-20
IN139259B (xx) 1976-05-29
AR203896A1 (es) 1975-10-31
AR203636A1 (es) 1975-09-30
AU6384773A (en) 1975-06-26
GB1460916A (en) 1977-01-06
GB1460915A (en) 1977-01-06
AR205560A1 (es) 1976-05-14
SU576948A3 (ru) 1977-10-15
DD116602A5 (xx) 1975-12-05
JPS5191224A (en) 1976-08-10

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Legal Events

Date Code Title Description
OI Miscellaneous see part 1
OHW Rejection