DE2343037A1 - Arzneimittel mit antidepressiver wirkung - Google Patents

Arzneimittel mit antidepressiver wirkung

Info

Publication number
DE2343037A1
DE2343037A1 DE19732343037 DE2343037A DE2343037A1 DE 2343037 A1 DE2343037 A1 DE 2343037A1 DE 19732343037 DE19732343037 DE 19732343037 DE 2343037 A DE2343037 A DE 2343037A DE 2343037 A1 DE2343037 A1 DE 2343037A1
Authority
DE
Germany
Prior art keywords
prolinamide
effect
pyroglutamyl
medicinal products
trh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19732343037
Other languages
German (de)
English (en)
Inventor
Rolf Dr Geiger
Wolfgang Dr Koenig
Hans-Joerg Dr Kruse
Hans Dr Wissmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Priority to DE19732343037 priority Critical patent/DE2343037A1/de
Priority to NL7411104A priority patent/NL7411104A/xx
Priority to AU72592/74A priority patent/AU7259274A/en
Priority to ZA00745423A priority patent/ZA745423B/xx
Priority to DK452374A priority patent/DK452374A/da
Priority to LU70784A priority patent/LU70784A1/xx
Priority to FR7429137A priority patent/FR2241307A1/fr
Priority to BE147919A priority patent/BE819200A/fr
Publication of DE2343037A1 publication Critical patent/DE2343037A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DE19732343037 1973-08-25 1973-08-25 Arzneimittel mit antidepressiver wirkung Pending DE2343037A1 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
DE19732343037 DE2343037A1 (de) 1973-08-25 1973-08-25 Arzneimittel mit antidepressiver wirkung
NL7411104A NL7411104A (nl) 1973-08-25 1974-08-20 Geneesmiddel met antidepressieve activiteit.
AU72592/74A AU7259274A (en) 1973-08-25 1974-08-22 Medicaments
ZA00745423A ZA745423B (en) 1973-08-25 1974-08-23 Medicaments having an antidepressive effect
DK452374A DK452374A (fr) 1973-08-25 1974-08-23
LU70784A LU70784A1 (fr) 1973-08-25 1974-08-23
FR7429137A FR2241307A1 (en) 1973-08-25 1974-08-26 Antidepressant peptide cpds. - contg. pyroglutamyl as the N-terminal amino-acid
BE147919A BE819200A (fr) 1973-08-25 1974-08-26 Medicament ayant un effet anti-depressif

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732343037 DE2343037A1 (de) 1973-08-25 1973-08-25 Arzneimittel mit antidepressiver wirkung

Publications (1)

Publication Number Publication Date
DE2343037A1 true DE2343037A1 (de) 1975-03-06

Family

ID=5890743

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19732343037 Pending DE2343037A1 (de) 1973-08-25 1973-08-25 Arzneimittel mit antidepressiver wirkung

Country Status (8)

Country Link
AU (1) AU7259274A (fr)
BE (1) BE819200A (fr)
DE (1) DE2343037A1 (fr)
DK (1) DK452374A (fr)
FR (1) FR2241307A1 (fr)
LU (1) LU70784A1 (fr)
NL (1) NL7411104A (fr)
ZA (1) ZA745423B (fr)

Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3024256A1 (de) * 1979-06-28 1981-01-08 Richter Gedeon Vegyeszet Peptidamide, verfahren zur herstellung derselben und diese enthaltende arzneimittel
US5766633A (en) 1993-04-22 1998-06-16 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5773647A (en) * 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5776888A (en) * 1997-02-07 1998-07-07 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5804688A (en) 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5811127A (en) 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5824345A (en) 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
US5863944A (en) 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5879681A (en) 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US5935601A (en) * 1994-04-22 1999-08-10 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5939381A (en) 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5955503A (en) 1993-04-22 1999-09-21 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
US5972387A (en) 1992-12-21 1999-10-26 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5990166A (en) 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6051258A (en) 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US6051561A (en) * 1997-02-07 2000-04-18 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US6060513A (en) 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6071538A (en) 1992-06-15 2000-06-06 Emisphere Technologies, Inc. Oral delivery composition comprising supramolecular complex
US6071510A (en) 1995-03-31 2000-06-06 Emisphere Technologies, Inc. Modified amino acids and compositions comprising the same for delivering active agents
US6084112A (en) 1995-09-11 2000-07-04 Emisphere Technologies, Inc. Method for preparing ω-aminoalkanoic acid derivatives from cycloalkanones
US6099856A (en) 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US6100285A (en) 1995-06-07 2000-08-08 Emisphere Technologies, Inc. Method of solubilizing itraconazole
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US6242495B1 (en) 1997-02-07 2001-06-05 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6346242B1 (en) 1995-03-31 2002-02-12 Emishpere Technologies, Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6375983B1 (en) 1996-06-14 2002-04-23 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US6413550B1 (en) 1992-06-15 2002-07-02 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
EP1893192A2 (fr) * 2005-06-08 2008-03-05 The University of North Carolina At Chapel Hill Methodes facilitant la survie de cellules neurales a l'aide de mimetiques non-peptidiques et peptidiques de neurotrophine du type bdnf
US9828332B2 (en) 2013-03-15 2017-11-28 PharmatorophiX, Inc. Non-peptide BDNF neurotrophin mimetics
US9828330B2 (en) 2013-03-15 2017-11-28 Pharmatrophix, Inc. Non-peptide BDNF neurotrophin mimetics

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4125578A (en) * 1977-11-09 1979-05-17 Merck & Co Inc Tripeptides
HU184481B (en) * 1981-10-02 1984-08-28 Richter Gedeon Vegyeszet Process for producing tripeptides for diminishing appetite
IT1186733B (it) * 1985-06-05 1987-12-16 Eniricerche Spa Composti tripeptidici ad azione ipotensiva

Cited By (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3024256A1 (de) * 1979-06-28 1981-01-08 Richter Gedeon Vegyeszet Peptidamide, verfahren zur herstellung derselben und diese enthaltende arzneimittel
US6413550B1 (en) 1992-06-15 2002-07-02 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US6348207B1 (en) 1992-06-15 2002-02-19 Emisiphere Technologies, Inc. Orally deliverable supramolecular complex
US6245359B1 (en) 1992-06-15 2001-06-12 Emisphere Technologies, Inc. Active agent transport systems
US5811127A (en) 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US6099856A (en) 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US6071538A (en) 1992-06-15 2000-06-06 Emisphere Technologies, Inc. Oral delivery composition comprising supramolecular complex
US5972387A (en) 1992-12-21 1999-10-26 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5955503A (en) 1993-04-22 1999-09-21 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5766633A (en) 1993-04-22 1998-06-16 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US6100298A (en) 1993-04-22 2000-08-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5935601A (en) * 1994-04-22 1999-08-10 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US6180140B1 (en) 1994-04-22 2001-01-30 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US6428780B2 (en) 1995-03-31 2002-08-06 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6346242B1 (en) 1995-03-31 2002-02-12 Emishpere Technologies, Inc. Compounds and compositions for delivering active agents
US6071510A (en) 1995-03-31 2000-06-06 Emisphere Technologies, Inc. Modified amino acids and compositions comprising the same for delivering active agents
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5824345A (en) 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
US6461545B1 (en) 1995-06-07 2002-10-08 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US6051258A (en) 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US6100285A (en) 1995-06-07 2000-08-08 Emisphere Technologies, Inc. Method of solubilizing itraconazole
US6084112A (en) 1995-09-11 2000-07-04 Emisphere Technologies, Inc. Method for preparing ω-aminoalkanoic acid derivatives from cycloalkanones
US6375983B1 (en) 1996-06-14 2002-04-23 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US6060513A (en) 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5773647A (en) * 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US8686154B2 (en) 1997-02-07 2014-04-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6242495B1 (en) 1997-02-07 2001-06-05 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5879681A (en) 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US5990166A (en) 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5939381A (en) 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6051561A (en) * 1997-02-07 2000-04-18 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US5776888A (en) * 1997-02-07 1998-07-07 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5804688A (en) 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
EP1893192A2 (fr) * 2005-06-08 2008-03-05 The University of North Carolina At Chapel Hill Methodes facilitant la survie de cellules neurales a l'aide de mimetiques non-peptidiques et peptidiques de neurotrophine du type bdnf
EP1893192A4 (fr) * 2005-06-08 2010-03-31 Univ North Carolina Methodes facilitant la survie de cellules neurales a l'aide de mimetiques non-peptidiques et peptidiques de neurotrophine du type bdnf
US8686045B2 (en) 2005-06-08 2014-04-01 The University Of North Carolina At Chapel Hill Methods of facilitating neural cell survival using non-peptide and peptide BDNF neurotrophin mimetics
US9604907B2 (en) 2005-06-08 2017-03-28 The University Of North Carolina At Chapel Hill Methods of facilitating neural cell survival using non-peptide and peptide BDNF neurotrophin mimetics
US9828332B2 (en) 2013-03-15 2017-11-28 PharmatorophiX, Inc. Non-peptide BDNF neurotrophin mimetics
US9828330B2 (en) 2013-03-15 2017-11-28 Pharmatrophix, Inc. Non-peptide BDNF neurotrophin mimetics

Also Published As

Publication number Publication date
DK452374A (fr) 1975-04-28
ZA745423B (en) 1975-08-27
AU7259274A (en) 1976-02-26
NL7411104A (nl) 1975-02-27
BE819200A (fr) 1975-02-26
LU70784A1 (fr) 1976-08-19
FR2241307B1 (fr) 1978-07-21
FR2241307A1 (en) 1975-03-21

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