FR2241307A1 - Antidepressant peptide cpds. - contg. pyroglutamyl as the N-terminal amino-acid - Google Patents

Antidepressant peptide cpds. - contg. pyroglutamyl as the N-terminal amino-acid

Info

Publication number
FR2241307A1
FR2241307A1 FR7429137A FR7429137A FR2241307A1 FR 2241307 A1 FR2241307 A1 FR 2241307A1 FR 7429137 A FR7429137 A FR 7429137A FR 7429137 A FR7429137 A FR 7429137A FR 2241307 A1 FR2241307 A1 FR 2241307A1
Authority
FR
France
Prior art keywords
pyroglutamyl
prolinamide
antidepressant
peptide
cpds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7429137A
Other languages
English (en)
Other versions
FR2241307B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of FR2241307A1 publication Critical patent/FR2241307A1/fr
Application granted granted Critical
Publication of FR2241307B1 publication Critical patent/FR2241307B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
FR7429137A 1973-08-25 1974-08-26 Antidepressant peptide cpds. - contg. pyroglutamyl as the N-terminal amino-acid Granted FR2241307A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732343037 DE2343037A1 (de) 1973-08-25 1973-08-25 Arzneimittel mit antidepressiver wirkung

Publications (2)

Publication Number Publication Date
FR2241307A1 true FR2241307A1 (en) 1975-03-21
FR2241307B1 FR2241307B1 (fr) 1978-07-21

Family

ID=5890743

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7429137A Granted FR2241307A1 (en) 1973-08-25 1974-08-26 Antidepressant peptide cpds. - contg. pyroglutamyl as the N-terminal amino-acid

Country Status (8)

Country Link
AU (1) AU7259274A (fr)
BE (1) BE819200A (fr)
DE (1) DE2343037A1 (fr)
DK (1) DK452374A (fr)
FR (1) FR2241307A1 (fr)
LU (1) LU70784A1 (fr)
NL (1) NL7411104A (fr)
ZA (1) ZA745423B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0001845A2 (fr) * 1977-11-09 1979-05-16 Merck & Co. Inc. Tripeptides analeptiques, procédé pour leur préparation et leur composition pharmaceutique
FR2513994A1 (fr) * 1981-10-02 1983-04-08 Richter Gedeon Vegyeszet Tripeptides anorexigenes, procede pour leur preparation et compositions pharmaceutiques les contenant
EP0204374A2 (fr) * 1985-06-05 1986-12-10 POLIFARMA S.p.A. Composés tripeptides ayant une activité hypotensive

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180926B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US6099856A (en) 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5811127A (en) 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5401516A (en) 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
EP1025840B1 (fr) 1993-04-22 2005-06-29 Emisphere Technologies, Inc. Compositions pour l'administration par voie orale
US5643957A (en) 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
CN1151836C (zh) 1995-03-31 2004-06-02 艾米斯菲尔技术有限公司 用作传送活性剂的化合物和组合物
US6051258A (en) 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US5824345A (en) 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
WO1997010197A1 (fr) 1995-09-11 1997-03-20 Emisphere Technologies, Inc. PROCEDE POUR PREPARER DES DERIVES D'ACIDES φ-AMINOALCANOIQUES A PARTIR DE CYCLOALCANONES
EP0904065A4 (fr) 1996-06-14 2000-06-14 Emisphere Tech Inc Parfums microencapsules et leur procede de production
US5939381A (en) 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6051561A (en) * 1997-02-07 2000-04-18 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US5776888A (en) * 1997-02-07 1998-07-07 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5879681A (en) 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US5773647A (en) * 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5804688A (en) 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6060513A (en) 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5990166A (en) 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
WO2006133353A2 (fr) 2005-06-08 2006-12-14 The University Of North Carolina At Chapel Hill Methodes facilitant la survie de cellules neurales a l'aide de mimetiques non-peptidiques et peptidiques de neurotrophine du type bdnf
CN105189449A (zh) 2013-03-15 2015-12-23 特罗菲克斯制药股份有限公司 非肽bdnf神经营养蛋白模拟物
RU2015141934A (ru) 2013-03-15 2017-04-20 Фарматрофикс, Инк. Непептидные миметики нейротрофина bdnf

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0001845A2 (fr) * 1977-11-09 1979-05-16 Merck & Co. Inc. Tripeptides analeptiques, procédé pour leur préparation et leur composition pharmaceutique
EP0001845A3 (fr) * 1977-11-09 1979-05-30 Merck & Co. Inc. Tripeptides analeptiques, procédé pour leur préparation et leur composition pharmaceutique
FR2513994A1 (fr) * 1981-10-02 1983-04-08 Richter Gedeon Vegyeszet Tripeptides anorexigenes, procede pour leur preparation et compositions pharmaceutiques les contenant
EP0204374A2 (fr) * 1985-06-05 1986-12-10 POLIFARMA S.p.A. Composés tripeptides ayant une activité hypotensive
EP0204374A3 (en) * 1985-06-05 1988-07-13 Eniricerche S.P.A. Tripeptidic compounds having hypotensive activity

Also Published As

Publication number Publication date
FR2241307B1 (fr) 1978-07-21
AU7259274A (en) 1976-02-26
BE819200A (fr) 1975-02-26
DK452374A (fr) 1975-04-28
NL7411104A (nl) 1975-02-27
DE2343037A1 (de) 1975-03-06
ZA745423B (en) 1975-08-27
LU70784A1 (fr) 1976-08-19

Similar Documents

Publication Publication Date Title
FR2241307A1 (en) Antidepressant peptide cpds. - contg. pyroglutamyl as the N-terminal amino-acid
ZA7468B (en) Compositions and treatment of proliferatave skin diseases with phosphodiesterase inhibitors
SE385227B (sv) Forfarande for minskning av strevhet hos typer som innehaller bomull genom behandling med en vattenhaltig losning av cellulolytiska enzymer samt komposition for anvendning vid forfarandet
CH399642A (de) Verfahren zur automatischen Anpassung der Fördermenge von Drehkolbenverdichtern der Vielzellenbauart an den tatsächlichen Bedarf und Vorrichtung zur Durchführung des Verfahrens
NO883614D0 (no) Molekylaer kloning og ekspresjon av humant il-3.
ES404616A1 (es) Procedimiento para la obtencion de una composicion con ac- tividad anti-seborreica y de uso externo.
ES2149952T3 (es) L-arginina y analogos como inhibidores de la agregacion de trombocitos.
FR1275651A (fr) Préparation de polyamides d'acides beta-amino-carboxyliques
IL42787A0 (en) Composition and method for promotion of protein synthesis and suppression of urea formation in the body utilizing hydroxy-acid analogs of amino acids
BE823986A (fr) Amino-acides cylciques et sel de ces acides
MY6500010A (en) Improvements in or relating to the treatment of shaped articles comprising elastomeric polymers
GB1497211A (en) Soft moist animal diet feed
FR2034455A1 (fr) Nouvelles preparations pharmaceutiques
FR1242641A (fr) Copolymères utilisables comme couches d'impression
SU485817A1 (ru) Устройство дл ввода защитного газа в изложницу
FI34377A (fi) Förfarande för framställning av speciellt lätt färgbara fibrer av polyolefiner innehållande blandningar
FR1310M (fr) Agents thérapeutiques appartenant au groupe des anisoxyéthylamines.
CA600777A (en) Catalytic treatment of alumina in fluidized beds
CY303A (en) Therapeutic hypotensive compositions comprising phenylalanine derivatives and benzothiadiazine-1,1-dioxide derivatives
GB949076A (en) Preparation of polypeptide derivatives
FR1252762A (fr) Dispositif pour améliorer le confort des fauteuils
JPS5258961A (en) Electronic watch
AU247933B2 (en) Improvements in and relating tothe concentration and purification of penicillinase
ES193154U (es) Botellero-escanciador.
AU264389B2 (en) Improvements in or relating to the dimerisation of terminally unsaturated mono - olefins

Legal Events

Date Code Title Description
ST Notification of lapse