DE2262139C2 - Verwendung von Dimethyl-2,2-dichlorvinyl-phosphat zur Bekämpfung der ersten Entwicklungsstufe von Bremsenlarven bei Pferden - Google Patents
Verwendung von Dimethyl-2,2-dichlorvinyl-phosphat zur Bekämpfung der ersten Entwicklungsstufe von Bremsenlarven bei PferdenInfo
- Publication number
- DE2262139C2 DE2262139C2 DE2262139A DE2262139A DE2262139C2 DE 2262139 C2 DE2262139 C2 DE 2262139C2 DE 2262139 A DE2262139 A DE 2262139A DE 2262139 A DE2262139 A DE 2262139A DE 2262139 C2 DE2262139 C2 DE 2262139C2
- Authority
- DE
- Germany
- Prior art keywords
- horse
- paste
- development
- larvae
- stage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241000283086 Equidae Species 0.000 title claims description 14
- 241000255632 Tabanus atratus Species 0.000 title claims description 10
- OEBRKCOSUFCWJD-UHFFFAOYSA-N dichlorvos Chemical compound COP(=O)(OC)OC=C(Cl)Cl OEBRKCOSUFCWJD-UHFFFAOYSA-N 0.000 title description 58
- 210000002784 stomach Anatomy 0.000 claims description 17
- 244000045947 parasite Species 0.000 claims description 15
- 239000003921 oil Substances 0.000 claims description 11
- 235000019198 oils Nutrition 0.000 claims description 11
- 210000000936 intestine Anatomy 0.000 claims description 10
- 241001465754 Metazoa Species 0.000 claims description 9
- 235000012343 cottonseed oil Nutrition 0.000 claims description 6
- 239000002385 cottonseed oil Substances 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 5
- 208000015181 infectious disease Diseases 0.000 claims description 5
- 210000003800 pharynx Anatomy 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 5
- 241001660203 Gasterophilus Species 0.000 claims description 4
- 230000006378 damage Effects 0.000 claims description 4
- 210000001519 tissue Anatomy 0.000 claims description 4
- 230000001418 larval effect Effects 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 239000011347 resin Substances 0.000 claims description 3
- 229920005989 resin Polymers 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 claims description 2
- 230000000507 anthelmentic effect Effects 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 230000009747 swallowing Effects 0.000 claims description 2
- 239000003440 toxic substance Substances 0.000 claims description 2
- 238000011282 treatment Methods 0.000 claims description 2
- 235000013601 eggs Nutrition 0.000 claims 5
- 235000013305 food Nutrition 0.000 claims 3
- 208000027418 Wounds and injury Diseases 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 230000002496 gastric effect Effects 0.000 claims 2
- 208000014674 injury Diseases 0.000 claims 2
- 210000004072 lung Anatomy 0.000 claims 2
- 210000003254 palate Anatomy 0.000 claims 2
- 206010003497 Asphyxia Diseases 0.000 claims 1
- 241000255925 Diptera Species 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 206010024264 Lethargy Diseases 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 208000025865 Ulcer Diseases 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000037213 diet Effects 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 230000001079 digestive effect Effects 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000001198 duodenum Anatomy 0.000 claims 1
- 244000079386 endoparasite Species 0.000 claims 1
- 210000003238 esophagus Anatomy 0.000 claims 1
- 210000003608 fece Anatomy 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 claims 1
- -1 organophosphates Chemical class 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 231100000614 poison Toxicity 0.000 claims 1
- 230000036269 ulceration Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 description 9
- 229920000915 polyvinyl chloride Polymers 0.000 description 9
- 239000004800 polyvinyl chloride Substances 0.000 description 9
- 239000008119 colloidal silica Substances 0.000 description 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 238000002156 mixing Methods 0.000 description 5
- 239000008159 sesame oil Substances 0.000 description 5
- 235000011803 sesame oil Nutrition 0.000 description 5
- ZTHYODDOHIVTJV-UHFFFAOYSA-N Propyl gallate Chemical compound CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 description 4
- 241000255628 Tabanidae Species 0.000 description 4
- 239000011324 bead Substances 0.000 description 4
- 230000037396 body weight Effects 0.000 description 4
- 239000003995 emulsifying agent Substances 0.000 description 4
- 206010061217 Infestation Diseases 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000002285 corn oil Substances 0.000 description 3
- 235000005687 corn oil Nutrition 0.000 description 3
- 239000000155 melt Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 231100000252 nontoxic Toxicity 0.000 description 3
- 230000003000 nontoxic effect Effects 0.000 description 3
- 235000019271 petrolatum Nutrition 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000004322 Butylated hydroxytoluene Substances 0.000 description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
- 241001660201 Gasterophilus intestinalis Species 0.000 description 2
- 241000347074 Haworthia truncata Species 0.000 description 2
- 241000158526 Nasalis Species 0.000 description 2
- 235000010354 butylated hydroxytoluene Nutrition 0.000 description 2
- 229940095259 butylated hydroxytoluene Drugs 0.000 description 2
- 241001233037 catfish Species 0.000 description 2
- 239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 210000001983 hard palate Anatomy 0.000 description 2
- 201000000615 hard palate cancer Diseases 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
- 238000013508 migration Methods 0.000 description 2
- 230000000069 prophylactic effect Effects 0.000 description 2
- 239000000473 propyl gallate Substances 0.000 description 2
- 235000010388 propyl gallate Nutrition 0.000 description 2
- 229940075579 propyl gallate Drugs 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 235000019489 Almond oil Nutrition 0.000 description 1
- UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical compound [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 description 1
- 241000167880 Hirundinidae Species 0.000 description 1
- 241000904715 Oxyuris Species 0.000 description 1
- 241000244187 Parascaris Species 0.000 description 1
- 208000030852 Parasitic disease Diseases 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- 239000004264 Petrolatum Substances 0.000 description 1
- 235000019485 Safflower oil Nutrition 0.000 description 1
- 244000000231 Sesamum indicum Species 0.000 description 1
- 235000003434 Sesamum indicum Nutrition 0.000 description 1
- 206010059516 Skin toxicity Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 241000122932 Strongylus Species 0.000 description 1
- 241000112708 Vates Species 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- ZTOJFFHGPLIVKC-CLFAGFIQSA-N abts Chemical compound S/1C2=CC(S(O)(=O)=O)=CC=C2N(CC)C\1=N\N=C1/SC2=CC(S(O)(=O)=O)=CC=C2N1CC ZTOJFFHGPLIVKC-CLFAGFIQSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- 229940124339 anthelmintic agent Drugs 0.000 description 1
- 239000000921 anthelmintic agent Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 229940043202 calcium cyclamate Drugs 0.000 description 1
- 210000004534 cecum Anatomy 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- LFVPBERIVUNMGV-UHFFFAOYSA-N fasudil hydrochloride Chemical compound Cl.C=1C=CC2=CN=CC=C2C=1S(=O)(=O)N1CCCNCC1 LFVPBERIVUNMGV-UHFFFAOYSA-N 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 235000013379 molasses Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 230000036281 parasite infection Effects 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000005871 repellent Substances 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 231100000438 skin toxicity Toxicity 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 229960001462 sodium cyclamate Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21170971A | 1971-12-23 | 1971-12-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2262139A1 DE2262139A1 (de) | 1973-07-05 |
| DE2262139C2 true DE2262139C2 (de) | 1985-05-15 |
Family
ID=22788036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2262139A Expired DE2262139C2 (de) | 1971-12-23 | 1972-12-19 | Verwendung von Dimethyl-2,2-dichlorvinyl-phosphat zur Bekämpfung der ersten Entwicklungsstufe von Bremsenlarven bei Pferden |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3746490A (OSRAM) |
| AU (1) | AU471129B2 (OSRAM) |
| BE (1) | BE792990A (OSRAM) |
| DE (1) | DE2262139C2 (OSRAM) |
| FR (1) | FR2177709B1 (OSRAM) |
| GB (1) | GB1372950A (OSRAM) |
| IT (1) | IT998084B (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4814170A (en) * | 1986-03-14 | 1989-03-21 | Aphton Corporation | Method for immunization against and treatment of infection by ectoparasites and endoparasites |
| US4891219A (en) * | 1986-03-14 | 1990-01-02 | Aphton Corporation | Method for immunization against and treatment of infection by ectoparasites and endoparasites |
| NZ224682A (en) * | 1987-06-16 | 1990-06-26 | Warner Lambert Co | Topical pharmaceutical emulsion having increased viscosity comprising an oil and a complexing agent |
| SE9301489D0 (sv) * | 1993-04-30 | 1993-04-30 | Ab Astra | Veterinary composition |
| US6787342B2 (en) * | 2000-02-16 | 2004-09-07 | Merial Limited | Paste formulations |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3166472A (en) * | 1962-01-12 | 1965-01-19 | Shell Oil Co | Anthelmintic compositions and method of employing same |
| US3398225A (en) * | 1964-11-02 | 1968-08-20 | Shell Oil Co | Coated 2, 2-dichlorovinyl phosphate and polyvinyl chloride resin anthelmintic compositions |
| US3630896A (en) * | 1968-07-12 | 1971-12-28 | Hideto Oka | Agricultural chemical composition in solid or jelly form |
-
0
- BE BE792990D patent/BE792990A/xx not_active IP Right Cessation
-
1971
- 1971-12-23 US US00211709A patent/US3746490A/en not_active Expired - Lifetime
-
1972
- 1972-12-19 DE DE2262139A patent/DE2262139C2/de not_active Expired
- 1972-12-21 AU AU50384/72A patent/AU471129B2/en not_active Expired
- 1972-12-21 FR FR7245674A patent/FR2177709B1/fr not_active Expired
- 1972-12-21 GB GB5908472A patent/GB1372950A/en not_active Expired
- 1972-12-21 IT IT33386/72A patent/IT998084B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| GB1372950A (en) | 1974-11-06 |
| AU5038472A (en) | 1974-06-27 |
| IT998084B (it) | 1976-01-20 |
| BE792990A (fr) | 1973-06-19 |
| DE2262139A1 (de) | 1973-07-05 |
| AU471129B2 (en) | 1974-06-27 |
| FR2177709A1 (OSRAM) | 1973-11-09 |
| FR2177709B1 (OSRAM) | 1976-10-29 |
| US3746490A (en) | 1973-07-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OD | Request for examination | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |