DE2241513C3 - Verfahren zur analytischen Bestimmung der Sequenzen eines Polynucleotids - Google Patents

Verfahren zur analytischen Bestimmung der Sequenzen eines Polynucleotids

Info

Publication number
DE2241513C3
DE2241513C3 DE2241513A DE2241513A DE2241513C3 DE 2241513 C3 DE2241513 C3 DE 2241513C3 DE 2241513 A DE2241513 A DE 2241513A DE 2241513 A DE2241513 A DE 2241513A DE 2241513 C3 DE2241513 C3 DE 2241513C3
Authority
DE
Germany
Prior art keywords
polynucleotide
terminal
nucleoside
adsorbed
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2241513A
Other languages
German (de)
English (en)
Other versions
DE2241513B2 (de
DE2241513A1 (de
Inventor
Peter Thomas West Lafayette Ind. Gilham (V.St.A.)
Herbert Lee Cambridge Weith (Grossbritannien)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Research Foundation
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of DE2241513A1 publication Critical patent/DE2241513A1/de
Publication of DE2241513B2 publication Critical patent/DE2241513B2/de
Application granted granted Critical
Publication of DE2241513C3 publication Critical patent/DE2241513C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE2241513A 1971-08-27 1972-08-24 Verfahren zur analytischen Bestimmung der Sequenzen eines Polynucleotids Expired DE2241513C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17575671A 1971-08-27 1971-08-27

Publications (3)

Publication Number Publication Date
DE2241513A1 DE2241513A1 (de) 1973-03-15
DE2241513B2 DE2241513B2 (de) 1973-11-15
DE2241513C3 true DE2241513C3 (de) 1974-06-12

Family

ID=22641511

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2241513A Expired DE2241513C3 (de) 1971-08-27 1972-08-24 Verfahren zur analytischen Bestimmung der Sequenzen eines Polynucleotids

Country Status (8)

Country Link
US (1) US3730844A (enrdf_load_html_response)
JP (1) JPS5123359B2 (enrdf_load_html_response)
CA (1) CA977660A (enrdf_load_html_response)
DE (1) DE2241513C3 (enrdf_load_html_response)
FR (1) FR2151941A5 (enrdf_load_html_response)
GB (1) GB1398728A (enrdf_load_html_response)
IT (1) IT994037B (enrdf_load_html_response)
SE (1) SE376656B (enrdf_load_html_response)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2514275A1 (de) * 1975-03-27 1976-10-14 Schering Ag Verfahren zur herstellung von n- (polysaccharidyl)-stickstoffheterocyclen, insbesondere von pyrimidin- oder purinbasen
JPS55149546U (enrdf_load_html_response) * 1979-04-16 1980-10-28
US4302204A (en) * 1979-07-02 1981-11-24 The Board Of Trustees Of Leland Stanford Junior University Transfer and detection of nucleic acids
GB2059421A (en) * 1979-10-03 1981-04-23 Self C H Assay method and reagents therefor
US4446231A (en) * 1979-10-03 1984-05-01 Self Colin H Immunoassay using an amplified cyclic detection system
US4704256A (en) * 1980-09-23 1987-11-03 California Institute Of Technology Apparatus for the sequential performance of chemical processes
EP0060123B1 (en) * 1981-03-07 1986-10-29 Colin Henry Self Assay and use
JPS5913644U (ja) * 1982-04-24 1984-01-27 三國工業株式会社 スロツトルバルブの空気量調整装置
DE3312929A1 (de) * 1982-06-02 1983-12-08 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig Verfahren zur sequenzanalyse eines gegebenenfalls modifizierten oligoribonukleotids oder oligodesoxyribonukletids
JPS60187347U (ja) * 1984-05-22 1985-12-12 小松ゼノア株式会社 気化器
US4962037A (en) 1987-10-07 1990-10-09 United States Of America Method for rapid base sequencing in DNA and RNA
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5925525A (en) * 1989-06-07 1999-07-20 Affymetrix, Inc. Method of identifying nucleotide differences
US20060194258A1 (en) * 1989-06-07 2006-08-31 Affymetrix, Inc. Polypeptide array synthesis
US6919211B1 (en) * 1989-06-07 2005-07-19 Affymetrix, Inc. Polypeptide arrays
US6955915B2 (en) * 1989-06-07 2005-10-18 Affymetrix, Inc. Apparatus comprising polymers
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US6416952B1 (en) 1989-06-07 2002-07-09 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
US6551784B2 (en) 1989-06-07 2003-04-22 Affymetrix Inc Method of comparing nucleic acid sequences
DE69132843T2 (de) * 1990-12-06 2002-09-12 Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) Identifizierung von Nukleinsäuren in Proben
US6943034B1 (en) * 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US6864101B1 (en) 1991-11-22 2005-03-08 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US7378236B1 (en) 1994-06-17 2008-05-27 The Board Of Trustees Of The Leland Stanford Junior University Method for analyzing gene expression patterns
US5807522A (en) * 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US7323298B1 (en) 1994-06-17 2008-01-29 The Board Of Trustees Of The Leland Stanford Junior University Microarray for determining the relative abundances of polynuceotide sequences
US8236493B2 (en) * 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
EP0880598A4 (en) * 1996-01-23 2005-02-23 Affymetrix Inc RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
CN104316621B (zh) * 2014-11-17 2017-01-11 上海征泰饲料有限公司 蛋白产品的总核苷酸测定方法

Also Published As

Publication number Publication date
SE376656B (enrdf_load_html_response) 1975-06-02
FR2151941A5 (enrdf_load_html_response) 1973-04-20
DE2241513B2 (de) 1973-11-15
JPS4835890A (enrdf_load_html_response) 1973-05-26
CA977660A (en) 1975-11-11
GB1398728A (en) 1975-06-25
DE2241513A1 (de) 1973-03-15
US3730844A (en) 1973-05-01
JPS5123359B2 (enrdf_load_html_response) 1976-07-16
IT994037B (it) 1975-10-20

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977
EHJ Ceased/non-payment of the annual fee