DE2125634A1 - Verfahren zur Herstellung von neuen Cycloheptenderivaten - Google Patents

Verfahren zur Herstellung von neuen Cycloheptenderivaten

Info

Publication number
DE2125634A1
DE2125634A1 DE19712125634 DE2125634A DE2125634A1 DE 2125634 A1 DE2125634 A1 DE 2125634A1 DE 19712125634 DE19712125634 DE 19712125634 DE 2125634 A DE2125634 A DE 2125634A DE 2125634 A1 DE2125634 A1 DE 2125634A1
Authority
DE
Germany
Prior art keywords
dibenzo
pyrrole
general formula
tetrahydro
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19712125634
Other languages
German (de)
English (en)
Inventor
Jacques Dr. Basel; Schindler Walter Dr. Riehen Gosteli (verstorben); (Schweiz)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE2125634A1 publication Critical patent/DE2125634A1/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/30Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
    • C07C2603/32Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Primary Cells (AREA)
  • Hybrid Cells (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19712125634 1970-05-25 1971-05-24 Verfahren zur Herstellung von neuen Cycloheptenderivaten Pending DE2125634A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH767270A CH532038A (de) 1970-05-25 1970-05-25 Verfahren zur Herstellung von neuen Cycloheptenderivaten

Publications (1)

Publication Number Publication Date
DE2125634A1 true DE2125634A1 (de) 1972-01-05

Family

ID=4328785

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712125634 Pending DE2125634A1 (de) 1970-05-25 1971-05-24 Verfahren zur Herstellung von neuen Cycloheptenderivaten

Country Status (19)

Country Link
US (2) US3726897A (pl)
AT (2) AT302287B (pl)
BE (1) BE767597A (pl)
CA (1) CA953719A (pl)
CH (1) CH532038A (pl)
CS (1) CS177036B2 (pl)
DE (1) DE2125634A1 (pl)
DK (2) DK135585C (pl)
ES (1) ES391497A1 (pl)
FR (1) FR2126967B1 (pl)
GB (1) GB1335129A (pl)
IE (1) IE35431B1 (pl)
IL (1) IL36903A (pl)
NL (1) NL7106827A (pl)
NO (1) NO130587C (pl)
PL (1) PL83825B1 (pl)
SE (1) SE358390B (pl)
SU (2) SU396020A3 (pl)
ZA (1) ZA713317B (pl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007450A1 (de) * 1978-07-07 1980-02-06 Ciba-Geigy Ag Azatetracyclische Carbonitrile, ihre Herstellung, pharmazeutische Präparate, die diese enthalten und deren Verwendung

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4088772A (en) * 1975-01-30 1978-05-09 E. I. Du Pont De Nemours And Company Methanodibenzocycloheptapyrroles
US4064139A (en) * 1975-04-07 1977-12-20 Merck & Co., Inc. Substituted 9,10-dihydroanthracen-9,10-imines
US4076830A (en) * 1976-04-07 1978-02-28 E. I. Du Pont De Nemours And Company Alkylmethanodibenzocycloheptapyrroles
US4271178A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 1,2,3,3a,8,12b-Hexahydro-dibenzo[b,f]pyrrolo[3,4-d]azepines and pharmaceutical use thereof
US4154836A (en) * 1976-05-24 1979-05-15 Akzona Incorporated Tension reducing 1,2,3,4,4a,13b-hexahydro-dibenz[2,3;6,7]oxepino[4,5-c]pyridines
US4271179A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 1,2,3,3a,8,12b-Hexahydro-dibenzo[1,2;5,6]cyclohepta[3,4-C]pyrroles and pharmaceutical use thereof
US4271177A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 2,3,3a,12b-Tetrahydro-1H-dibenzo[2,3;6,7]thiepino[4,5-c]pyrroles and pharmaceutical use thereof
EP0030916B1 (de) * 1979-12-10 1984-08-29 Ciba-Geigy Ag Azatetracyclische Carbonitrile
SE455836B (sv) * 1985-10-11 1988-08-15 Haessle Ab Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
SE450087B (sv) * 1985-10-11 1987-06-09 Haessle Ab Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial
SE8703881D0 (sv) * 1987-10-08 1987-10-08 Haessle Ab New pharmaceutical preparation
US5760246A (en) * 1996-12-17 1998-06-02 Biller; Scott A. Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method
HRP20020440B1 (en) * 2002-05-21 2008-02-29 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 1-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof
HRP20020441A2 (en) * 2002-05-21 2003-12-31 Pliva D D 1-oxa-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediate for preparation thereof
HRP20020452A2 (en) * 2002-05-23 2004-02-29 Pliva D D 1,2-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediates for preparation thereof
HRP20030160A2 (en) * 2003-03-06 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. 1-thiadibenzoazulene derivatives and biological action thereof
HRP20030956A2 (en) * 2003-11-21 2005-08-31 Pliva-Istra�iva�ki institut d.o.o. USE OF 1,2-DIAZA-DIBENZO[e,h]AZULENES FOR THE MANU
HRP20030954A2 (en) * 2003-11-21 2005-08-31 Pliva D.D. USE OF 1-AZA-DIBENZO[e,h]AZULENES FOR THE MANUFACTURENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS
HRP20030955A2 (en) * 2003-11-21 2005-08-31 Pliva-Istra�iva�ki institut d.o.o. USE OF 1-OXADIBENZO[e,h]AZULENES FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS
HRP20040104A2 (en) * 2004-01-30 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Use of benzonaphthoazulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders
US7601856B2 (en) * 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
US7662831B2 (en) * 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR145F (pl) * 1964-06-01
CH501007A (de) * 1968-11-27 1970-12-31 Ciba Geigy Ag Verfahren zur Herstellung von neuen Thiepin- und Oxepinderivaten
CH501650A (de) * 1968-12-19 1971-01-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007450A1 (de) * 1978-07-07 1980-02-06 Ciba-Geigy Ag Azatetracyclische Carbonitrile, ihre Herstellung, pharmazeutische Präparate, die diese enthalten und deren Verwendung

Also Published As

Publication number Publication date
DK135585B (da) 1977-05-23
ZA713317B (en) 1972-01-26
AT307398B (de) 1973-05-25
PL83825B1 (pl) 1976-02-28
BE767597A (fr) 1971-11-25
GB1335129A (en) 1973-10-24
AT302287B (de) 1972-10-10
NO130587C (pl) 1975-01-08
FR2126967B1 (pl) 1974-11-15
CH532038A (de) 1972-12-31
NO130587B (pl) 1974-09-30
IE35431L (en) 1971-11-25
ES391497A1 (es) 1973-06-16
NL7106827A (pl) 1971-11-29
FR2126967A1 (pl) 1972-10-13
US3773940A (en) 1973-11-20
SE358390B (pl) 1973-07-30
CS177036B2 (pl) 1977-07-29
SU396020A3 (pl) 1973-08-28
IL36903A0 (en) 1971-08-25
SU383288A3 (pl) 1973-05-25
US3726897A (en) 1973-04-10
IE35431B1 (en) 1976-02-18
DK135585C (da) 1977-10-31
IL36903A (en) 1973-07-30
CA953719A (en) 1974-08-27

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Legal Events

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OHA Expiration of time for request for examination