DE2109854C3 - 7beta-(D-5- Amino- 5-carboxyvaleramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carbonsäure und deren Salze, Verfahren zu Ihrer Herstellung und solche Verbindungen enthaltende Arzneimittel - Google Patents

7beta-(D-5- Amino- 5-carboxyvaleramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carbonsäure und deren Salze, Verfahren zu Ihrer Herstellung und solche Verbindungen enthaltende Arzneimittel

Info

Publication number
DE2109854C3
DE2109854C3 DE2109854A DE2109854A DE2109854C3 DE 2109854 C3 DE2109854 C3 DE 2109854C3 DE 2109854 A DE2109854 A DE 2109854A DE 2109854 A DE2109854 A DE 2109854A DE 2109854 C3 DE2109854 C3 DE 2109854C3
Authority
DE
Germany
Prior art keywords
colored
medium
salts
amino
cream
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2109854A
Other languages
German (de)
English (en)
Other versions
DE2109854A1 (de
DE2109854B2 (de
Inventor
Justo M Mata
Edward O Stapley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/115,779 external-priority patent/US4302578A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2109854A1 publication Critical patent/DE2109854A1/de
Publication of DE2109854B2 publication Critical patent/DE2109854B2/de
Application granted granted Critical
Publication of DE2109854C3 publication Critical patent/DE2109854C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/08—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin disubstituted in the 7 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE2109854A 1970-03-13 1971-03-02 7beta-(D-5- Amino- 5-carboxyvaleramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carbonsäure und deren Salze, Verfahren zu Ihrer Herstellung und solche Verbindungen enthaltende Arzneimittel Expired DE2109854C3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1949670A 1970-03-13 1970-03-13
US5131970A 1970-06-30 1970-06-30
US9659470A 1970-12-09 1970-12-09
US05/115,779 US4302578A (en) 1970-12-09 1971-02-16 Cephalosporin antibiotics

Publications (3)

Publication Number Publication Date
DE2109854A1 DE2109854A1 (de) 1971-09-23
DE2109854B2 DE2109854B2 (de) 1974-09-26
DE2109854C3 true DE2109854C3 (de) 1975-06-05

Family

ID=27486855

Family Applications (3)

Application Number Title Priority Date Filing Date
DE2109854A Expired DE2109854C3 (de) 1970-03-13 1971-03-02 7beta-(D-5- Amino- 5-carboxyvaleramido) -3- (carbamoyloxymethyl) -7-methoxy-3-cephem-4-carbonsäure und deren Salze, Verfahren zu Ihrer Herstellung und solche Verbindungen enthaltende Arzneimittel
DE19712166463 Pending DE2166463A1 (de) 1970-03-13 1971-03-02 Derivate der 7-beta-(d-5-amino-5carboxyvaleramido)-7-methoxy-3-cephem-4carbonsaeure
DE19712166462 Granted DE2166462B2 (de) 1970-03-13 1971-03-02 7 beta -(d-5-amino-5-carboxyvaleramido)-3-(alpha-methoxy-cinnamoyloxymethyl)-7-methoxy-3-cephem-4-carbonsaeure-verbindungen, verfahren zu ihrer herstellung und solche verbindungen enthaltende arzneimittel

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE19712166463 Pending DE2166463A1 (de) 1970-03-13 1971-03-02 Derivate der 7-beta-(d-5-amino-5carboxyvaleramido)-7-methoxy-3-cephem-4carbonsaeure
DE19712166462 Granted DE2166462B2 (de) 1970-03-13 1971-03-02 7 beta -(d-5-amino-5-carboxyvaleramido)-3-(alpha-methoxy-cinnamoyloxymethyl)-7-methoxy-3-cephem-4-carbonsaeure-verbindungen, verfahren zu ihrer herstellung und solche verbindungen enthaltende arzneimittel

Country Status (19)

Country Link
JP (1) JPS581919B1 (enExample)
AR (3) AR200370A1 (enExample)
BE (1) BE764160A (enExample)
CA (1) CA960169A (enExample)
CH (5) CH579576A5 (enExample)
DD (3) DD96254A5 (enExample)
DE (3) DE2109854C3 (enExample)
DK (1) DK131639C (enExample)
FI (1) FI51484C (enExample)
FR (1) FR2085702B1 (enExample)
GB (1) GB1321412A (enExample)
IE (1) IE35110B1 (enExample)
IL (1) IL36281A (enExample)
IT (1) IT1045524B (enExample)
NL (1) NL171285C (enExample)
NO (1) NO134219C (enExample)
PH (1) PH12292A (enExample)
SE (1) SE385713B (enExample)
YU (1) YU35164B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1040620A (en) * 1972-11-14 1978-10-17 Frank J. Urban 6-alkoxy-6-acylamidopenicillins 7-alkoxy-7-acylamido acetoxycephalosporins and process
US4065356A (en) 1976-02-12 1977-12-27 Merck & Co., Inc. Production of antibiotic FR-02A (efrotomycin) by streptomyces lactamdurans
US4327093A (en) 1978-10-24 1982-04-27 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds
JPS5931517B2 (ja) * 1978-12-12 1984-08-02 山之内製薬株式会社 新規７↓−メトキシセファロスポリン誘導体
US4379920A (en) * 1979-10-31 1983-04-12 Glaxo Group Limited Cephalosporins
EP0137365A3 (en) * 1983-09-06 1986-01-15 Takeda Chemical Industries, Ltd. Cephalosporins and their production
EP0160745A3 (en) * 1984-05-07 1986-11-05 Takeda Chemical Industries, Ltd. Cephem compounds and their production
KR20060061295A (ko) 2003-05-28 2006-06-07 디에스엠 아이피 어셋츠 비.브이. 세펨 화합물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4945594A (enExample) * 1972-09-08 1974-05-01

Also Published As

Publication number Publication date
YU35164B (en) 1980-09-25
FI51484C (fi) 1977-01-10
YU62671A (en) 1979-12-31
GB1321412A (en) 1973-06-27
NL171285B (nl) 1982-10-01
CH587856A5 (enExample) 1977-05-13
CA960169A (en) 1974-12-31
DD96254A5 (enExample) 1973-03-12
FI51484B (enExample) 1976-09-30
DE2166463A1 (de) 1974-05-02
FR2085702A1 (enExample) 1971-12-31
DD100002A5 (enExample) 1973-09-05
BE764160A (fr) 1971-09-13
AR200370A1 (es) 1974-11-08
DK131639C (da) 1976-01-12
DE2166462A1 (de) 1974-05-09
AR201142A1 (es) 1975-02-14
IL36281A (en) 1977-04-29
NO134219B (enExample) 1976-05-24
DK131639B (da) 1975-08-11
NO134219C (enExample) 1976-09-01
CH587911A5 (enExample) 1977-05-13
PH12292A (en) 1978-12-29
CH586226A5 (enExample) 1977-03-31
DE2109854A1 (de) 1971-09-23
CH579576A5 (enExample) 1976-09-15
DE2109854B2 (de) 1974-09-26
JPS581919B1 (enExample) 1983-01-13
CH589655A5 (enExample) 1977-07-15
IE35110B1 (en) 1975-11-12
FR2085702B1 (enExample) 1974-08-23
DD99166A5 (enExample) 1973-07-20
IT1045524B (it) 1980-05-10
IL36281A0 (en) 1971-04-28
NL171285C (nl) 1983-03-01
AR212149A1 (es) 1978-05-31
NL7103360A (enExample) 1971-09-15
IE35110L (en) 1971-09-13
SE385713B (sv) 1976-07-19
DE2166462B2 (de) 1977-01-20

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977