DE201085T1 - 6-phenyl-1,2,3,4,4a,5,6,10b-octahydrobenz(h)-isochinoline. - Google Patents

6-phenyl-1,2,3,4,4a,5,6,10b-octahydrobenz(h)-isochinoline.

Info

Publication number
DE201085T1
DE201085T1 DE198686106200T DE86106200T DE201085T1 DE 201085 T1 DE201085 T1 DE 201085T1 DE 198686106200 T DE198686106200 T DE 198686106200T DE 86106200 T DE86106200 T DE 86106200T DE 201085 T1 DE201085 T1 DE 201085T1
Authority
DE
Germany
Prior art keywords
octahydrobenz
isochinoline
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE198686106200T
Other languages
English (en)
Inventor
James Joseph Rochester New York 14624 Us Napier
Ronald Conrad Pittsford New York 14534 Us Griffith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pennwalt Corp
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Publication of DE201085T1 publication Critical patent/DE201085T1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE198686106200T 1985-05-07 1986-05-06 6-phenyl-1,2,3,4,4a,5,6,10b-octahydrobenz(h)-isochinoline. Pending DE201085T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/731,426 US4678791A (en) 1985-05-07 1985-05-07 6-phenyl-1,2-3,4,4a,5-6,10b-octahydrobenz(h)isoquinolines useful for treating depression

Publications (1)

Publication Number Publication Date
DE201085T1 true DE201085T1 (de) 1987-05-21

Family

ID=24939464

Family Applications (1)

Application Number Title Priority Date Filing Date
DE198686106200T Pending DE201085T1 (de) 1985-05-07 1986-05-06 6-phenyl-1,2,3,4,4a,5,6,10b-octahydrobenz(h)-isochinoline.

Country Status (4)

Country Link
US (1) US4678791A (de)
EP (1) EP0201085A3 (de)
JP (1) JPS61254565A (de)
DE (1) DE201085T1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3717395A1 (de) * 1987-05-23 1988-12-08 Basf Ag 5-phenyl-1,2,3a,4,5,9b-hexahydro-3h-benz(e) indole, ihre herstellung und verwendung als arzneimittel
US5180733A (en) * 1990-03-30 1993-01-19 Abbott Laboratories Biogenic amine uptake inhibitors
US5863928A (en) 1993-11-19 1999-01-26 The Board Of Governors For Higher Education The State Of Rhode Island And Providence Plantation. Octahydrobenzo f!quinoline-based receptor agonists and antagonists
US5475003A (en) * 1994-03-03 1995-12-12 Syntex (U.S.A.) Inc. 8-phenylcyclopentenoquinoline and 8-phenylcyclohexenoquinoline derivatives
EP0958285B1 (de) * 1997-01-08 2004-01-07 F.Hoffmann-La Roche Ag Tricyclische benz[e]isoindole und benz[h]isochinoline
MA26461A1 (fr) 1997-01-08 2004-12-20 Hoffmann La Roche Nouveaux benzo (e) isoindoles et benzo (h) isoquinoleines, medicaments les contenant, procedes pour leur preparation, et leur utilisation dans le traitement ou la prevention des troubles du systeme nerveux central.
US6900228B1 (en) 1998-03-10 2005-05-31 Research Triangle Institute Opiate compounds, methods of making and methods of use
US9359303B2 (en) * 2009-04-21 2016-06-07 Purdue Research Foundation Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH504438A (de) * 1968-05-27 1971-03-15 Sandoz Ag Verfahren zur Herstellung von 1,2,3,4,4a,5,6,10b-Octahydrobenz(h)isochinolin-6-on
US4022792A (en) * 1974-12-16 1977-05-10 Sterling Drug Inc. Methylidenepiperidines
DE2728831A1 (de) * 1976-07-06 1978-01-19 Sandoz Ag Organische verbindungen, ihre herstellung und verwendung
US4115387A (en) * 1977-11-25 1978-09-19 Morton-Norwich Products, Inc. 3-Methyl-4-phenyl-1,2,3,4-tetrahydrobenz [H]isoquinoline hydrobromide
US4166183A (en) * 1978-03-23 1979-08-28 E. R. Squibb & Sons, Inc. Tricyclic cyclitolamines
US4517187A (en) * 1982-10-18 1985-05-14 Pennwalt Corporation 1,3,4,6,7-11b-Hexahydro-7-phenyl-2H-pyrazino[2,1-a]isoquinolines methods of preparation, and use as antidepressants

Also Published As

Publication number Publication date
EP0201085A2 (de) 1986-11-12
US4678791A (en) 1987-07-07
EP0201085A3 (de) 1988-03-02
JPS61254565A (ja) 1986-11-12

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