DE2004201A1 - Neue 2,6-Bis(dialkanolamino)-pyrimido-[5,4-d]pyrimidine und Verfahren zu ihrer Herstellung - Google Patents

Neue 2,6-Bis(dialkanolamino)-pyrimido-[5,4-d]pyrimidine und Verfahren zu ihrer Herstellung

Info

Publication number
DE2004201A1
DE2004201A1 DE19702004201 DE2004201A DE2004201A1 DE 2004201 A1 DE2004201 A1 DE 2004201A1 DE 19702004201 DE19702004201 DE 19702004201 DE 2004201 A DE2004201 A DE 2004201A DE 2004201 A1 DE2004201 A1 DE 2004201A1
Authority
DE
Germany
Prior art keywords
radicals
piperidino
pyrimido
dialkanolamino
diethanolamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19702004201
Other languages
German (de)
English (en)
Inventor
Erich Dipl-Chem Dr Mueller
Berthold Dipl-Chem Dr Narr
Josef Dipl-Chem Dr Nickl
Josef Dipl-Chem Dr Roch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Priority to DE19702004201 priority Critical patent/DE2004201A1/de
Priority to RO65570A priority patent/RO57779A7/ro
Priority to RO68283A priority patent/RO58069A7/ro
Priority to ES387409A priority patent/ES387409A1/es
Priority to SU1613262A priority patent/SU379093A1/ru
Priority to NL7101118A priority patent/NL7101118A/xx
Priority to BG016681A priority patent/BG18612A3/xx
Priority to AU24767/71A priority patent/AU2476771A/en
Priority to ZA710579A priority patent/ZA71579B/xx
Priority to AT76771A priority patent/AT302313B/de
Priority to IL36097A priority patent/IL36097A0/xx
Priority to AT1020971A priority patent/AT302336B/de
Priority to BE762327A priority patent/BE762327A/xx
Priority to HUTO840A priority patent/HU163360B/hu
Priority to FR7103038A priority patent/FR2081471B1/fr
Priority to ES388479A priority patent/ES388479A1/es
Priority to GB2066071A priority patent/GB1313056A/en
Publication of DE2004201A1 publication Critical patent/DE2004201A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19702004201 1970-01-30 1970-01-30 Neue 2,6-Bis(dialkanolamino)-pyrimido-[5,4-d]pyrimidine und Verfahren zu ihrer Herstellung Pending DE2004201A1 (de)

Priority Applications (17)

Application Number Priority Date Filing Date Title
DE19702004201 DE2004201A1 (de) 1970-01-30 1970-01-30 Neue 2,6-Bis(dialkanolamino)-pyrimido-[5,4-d]pyrimidine und Verfahren zu ihrer Herstellung
RO65570A RO57779A7 (xx) 1970-01-30 1971-01-12
RO68283A RO58069A7 (xx) 1970-01-30 1971-01-12
ES387409A ES387409A1 (es) 1970-01-30 1971-01-19 Procedimiento para la preparacion de nuevas 2,6-bis (dial- canolamino) - pirimido (5,4-d) pirimidinas.
SU1613262A SU379093A1 (ru) 1971-01-25 СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ 2,6-бис- (ДИАЛКАНОЛАМИНО)-ПИРИМИДО
NL7101118A NL7101118A (xx) 1970-01-30 1971-01-28
BG016681A BG18612A3 (bg) 1970-01-30 1971-01-28 Метод за получаване на нови 2,6-бис(диалканоламино)-пиримидо (5,4-g)пиримидини
AU24767/71A AU2476771A (en) 1970-01-30 1971-01-28 Chemical compounds
ZA710579A ZA71579B (en) 1970-01-30 1971-01-29 Improvements relating to 2,6-bis(dialkanolamino)-pyrimido(5,4-d)pyrimidines
AT76771A AT302313B (de) 1970-01-30 1971-01-29 Verfahren zur Herstellung vonn neuen 2,6-Bis(dialkanolamino)-pyrimido[5,4-d]pyrimidinen
IL36097A IL36097A0 (en) 1970-01-30 1971-01-29 2,6-bis (dialkanolamino)-pyrimido (5,4-d) pyrimidines,their preparation and pharmaceutical compositions containing them
AT1020971A AT302336B (de) 1970-01-30 1971-01-29 Verfahren zur Herstellung von neuen 2,6-Bis(dialkanolamino)-pyrimido[5,4-d]pyrimidinen
BE762327A BE762327A (fr) 1970-01-30 1971-01-29 Nouvelles 2,6-bis(dialcanolamino)-pyrimido (5,4-d) pyrimidines et procedes pour les fabriquer
HUTO840A HU163360B (xx) 1970-01-30 1971-01-29
FR7103038A FR2081471B1 (xx) 1970-01-30 1971-01-29
ES388479A ES388479A1 (es) 1970-01-30 1971-02-20 Procedimiento para la preparacion de nuevas 2,6-bis (dial- canol-amino) - pirimido (5,4-d) pirimidinas.
GB2066071A GB1313056A (en) 1970-01-30 1971-04-19 Pyrimidopyrimidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702004201 DE2004201A1 (de) 1970-01-30 1970-01-30 Neue 2,6-Bis(dialkanolamino)-pyrimido-[5,4-d]pyrimidine und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
DE2004201A1 true DE2004201A1 (de) 1971-08-05

Family

ID=5760961

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19702004201 Pending DE2004201A1 (de) 1970-01-30 1970-01-30 Neue 2,6-Bis(dialkanolamino)-pyrimido-[5,4-d]pyrimidine und Verfahren zu ihrer Herstellung

Country Status (13)

Country Link
AT (2) AT302336B (xx)
AU (1) AU2476771A (xx)
BE (1) BE762327A (xx)
BG (1) BG18612A3 (xx)
DE (1) DE2004201A1 (xx)
ES (2) ES387409A1 (xx)
FR (1) FR2081471B1 (xx)
GB (1) GB1313056A (xx)
HU (1) HU163360B (xx)
IL (1) IL36097A0 (xx)
NL (1) NL7101118A (xx)
RO (2) RO58069A7 (xx)
ZA (1) ZA71579B (xx)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1116676B (de) * 1955-03-14 1961-11-09 Thomae Gmbh Dr K Verfahren zur Herstellung von Pyrimido [5, 4-d] pyrimidinen
GB1051218A (xx) * 1963-03-09
SU429582A3 (ru) * 1968-07-31 1974-05-25 Йозеф РОХ СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ 2,6-5ЯС- (ДИАЛКАНОЛАМИНО)ПИРИМИДО[5,4-с{] ПИРИМИДИНА1Предлагается способ получения новых производных пиримидо[5,4-(^] пиримидина, которые но сравнению с аналогичными производными лирИ1Мидо[5,4-??] пиримидина, описанными в литературе, обладают лучшими фармакологическими свойствами.Известен способ получения пи1римидо[5,4-й]- пиримидинов общей формулыпутем восстановления соединения общей формулы-1 Б10где два из радикалов Ri, R2, Rs и R4 —свободная или замещенная аминогруппа или свободная или замещенная гидразино- или гуани- диногруппа, а два других — водород или галоген, алкильный или арильный радикал, оксигруппа, свободная или замещенная алкил-, Эри.;!- ил'И диэтиламииоэтилгруппой, меркапто- группа, свободная или замещенная алкильным или арильным радикалом.152025где, по меньшей мере, один из радикалов Zi, 7.2, 2з и Z4 — галоген, другой из радикалов Zi, Za, Zs и Z4 — свободная или замещенная аминогруппа или свободная или замещ,енная гуанидино- или гидразиногруппа и еще один из радикалов Zi, Z^, Zg и Z4 — водород иди галоген, алкил или арил, оксигруппа, свободная или замещенная ал1кил-, арил- или диэтилами- ноэтилгруппой, .меркаптогруппа, свободная или замещенная алкильным или арильным радикалом, или свободная или замещенная аминогруппа.Предлагается спосо.б .получения новых производных 2,6-б«с-(диал1каноламино)пи1римидо- [5,4-а!]пиримидИ'На общей формулы

Also Published As

Publication number Publication date
AT302336B (de) 1972-10-10
ES388479A1 (es) 1973-05-01
AU2476771A (en) 1972-08-03
IL36097A0 (en) 1971-03-24
FR2081471A1 (xx) 1971-12-03
SU379093A3 (xx) 1973-04-18
FR2081471B1 (xx) 1974-09-06
NL7101118A (xx) 1971-08-03
RO58069A7 (xx) 1975-06-15
GB1313056A (en) 1973-04-11
HU163360B (xx) 1973-07-28
AT302313B (de) 1972-10-10
BE762327A (fr) 1971-07-29
ZA71579B (en) 1971-11-24
BG18612A3 (bg) 1975-02-25
ES387409A1 (es) 1973-05-16
RO57779A7 (xx) 1975-03-15

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