GB1051218A - - Google Patents
Info
- Publication number
- GB1051218A GB1051218A GB1051218DA GB1051218A GB 1051218 A GB1051218 A GB 1051218A GB 1051218D A GB1051218D A GB 1051218DA GB 1051218 A GB1051218 A GB 1051218A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- hydrogen atoms
- pyrimido
- symbols
- represent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DET0023605 | 1963-03-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1051218A true GB1051218A (xx) |
Family
ID=7551073
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1051218D Active GB1051218A (xx) | 1963-03-09 |
Country Status (5)
Country | Link |
---|---|
CH (1) | CH438344A (xx) |
DE (1) | DE1470341C3 (xx) |
FR (1) | FR3713M (xx) |
GB (1) | GB1051218A (xx) |
IT (1) | IT7950418A0 (xx) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4478833A (en) * | 1980-12-27 | 1984-10-23 | Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung | Trisubstituted pyrimido[5,4-d]pyrimidines and salts thereof |
EP2062580A1 (en) | 2003-04-24 | 2009-05-27 | Boehringer Ingelheim International GmbH | Use of dipyridamole or mopidamole for treatment and prevention of thromboembolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of trombin receptors |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2004201A1 (de) * | 1970-01-30 | 1971-08-05 | Thomae Gmbh Dr K | Neue 2,6-Bis(dialkanolamino)-pyrimido-[5,4-d]pyrimidine und Verfahren zu ihrer Herstellung |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US8034782B2 (en) | 2008-07-16 | 2011-10-11 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
CA3089569C (en) | 2007-06-04 | 2023-12-05 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
CA2930674A1 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
CA2828346C (en) | 2011-03-01 | 2021-01-26 | Synergy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
US9545446B2 (en) | 2013-02-25 | 2017-01-17 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
EP2968439A2 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
AU2014235215A1 (en) | 2013-03-15 | 2015-10-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法 |
CN105979959B (zh) | 2013-08-09 | 2021-11-30 | 阿德利克斯公司 | 用于抑制磷酸盐转运的化合物和方法 |
US20200368223A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
MX2023012060A (es) | 2021-04-13 | 2024-01-22 | Nuvalent Inc | Heterociclos con sustitucion amino para tratar canceres con mutaciones de egfr. |
-
0
- GB GB1051218D patent/GB1051218A/en active Active
-
1963
- 1963-03-09 DE DE1470341A patent/DE1470341C3/de not_active Expired
-
1964
- 1964-02-28 CH CH247764A patent/CH438344A/de unknown
- 1964-06-08 FR FR977447A patent/FR3713M/fr active Active
-
1979
- 1979-10-01 IT IT7950418A patent/IT7950418A0/it unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4478833A (en) * | 1980-12-27 | 1984-10-23 | Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung | Trisubstituted pyrimido[5,4-d]pyrimidines and salts thereof |
EP2062580A1 (en) | 2003-04-24 | 2009-05-27 | Boehringer Ingelheim International GmbH | Use of dipyridamole or mopidamole for treatment and prevention of thromboembolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of trombin receptors |
Also Published As
Publication number | Publication date |
---|---|
DE1470341B2 (de) | 1973-12-06 |
IT7950418A0 (it) | 1979-10-01 |
DE1470341C3 (de) | 1974-07-04 |
CH438344A (de) | 1967-06-30 |
FR3713M (fr) | 1965-11-29 |
DE1470341A1 (de) | 1969-07-03 |
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