CH438344A - Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen - Google Patents
Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinenInfo
- Publication number
- CH438344A CH438344A CH247764A CH247764A CH438344A CH 438344 A CH438344 A CH 438344A CH 247764 A CH247764 A CH 247764A CH 247764 A CH247764 A CH 247764A CH 438344 A CH438344 A CH 438344A
- Authority
- CH
- Switzerland
- Prior art keywords
- pyrimidines
- preparation
- basic substituted
- substituted pyrimido
- pyrimido
- Prior art date
Links
- JOZPEVMCAKXSEY-UHFFFAOYSA-N pyrimido[5,4-d]pyrimidine Chemical class N1=CN=CC2=NC=NC=C21 JOZPEVMCAKXSEY-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DET0023605 | 1963-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH438344A true CH438344A (de) | 1967-06-30 |
Family
ID=7551073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH247764A CH438344A (de) | 1963-03-09 | 1964-02-28 | Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen |
Country Status (5)
| Country | Link |
|---|---|
| CH (1) | CH438344A (de) |
| DE (1) | DE1470341C3 (de) |
| FR (1) | FR3713M (de) |
| GB (1) | GB1051218A (de) |
| IT (1) | IT7950418A0 (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2081471A1 (de) * | 1970-01-30 | 1971-12-03 | Thomae Gmbh Dr K |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3049207A1 (de) * | 1980-12-27 | 1982-07-29 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue trisubstituierte pyrimido (5,4-d) pyrimidine, ihre herstellung und ihre verwendung als arzneimittel |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| EP2062580A1 (de) | 2003-04-24 | 2009-05-27 | Boehringer Ingelheim International GmbH | Verwendung von Dipyridamol oder Mopidamol zur Behandlung und Prävention thromboembolischer Erkrankungen oder Störungen, die von einer übermäßigen Thrombinbildung und/oder einer erhöhten Expression von Thrombinrezeptoren verursacht werden |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA3089569C (en) | 2007-06-04 | 2023-12-05 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| WO2009149279A2 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| CA2730603C (en) | 2008-07-16 | 2019-09-24 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| DK2681236T3 (en) | 2011-03-01 | 2018-04-16 | Synergy Pharmaceuticals Inc | PROCEDURE FOR MANUFACTURING GUANYLATE CYCLASE-C-AGONISTS |
| EP3718557A3 (de) | 2013-02-25 | 2020-10-21 | Bausch Health Ireland Limited | Guanylat-cyclase-rezeptoragonist sp-333 zur verwendung in der darmreinigung |
| JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
| EP2970384A1 (de) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonisten der guanylatcyclase und deren verwendungen |
| PL3004138T3 (pl) | 2013-06-05 | 2024-07-29 | Bausch Health Ireland Limited | Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie |
| EP3030252B1 (de) | 2013-08-09 | 2018-11-07 | Ardelyx, Inc. | Verbindungen und verfahren zur hemmung eines phosphattransports |
| CN114340631A (zh) | 2019-05-21 | 2022-04-12 | 阿德利克斯股份有限公司 | 用于降低患者的血清磷酸盐的组合 |
| US12037346B2 (en) | 2021-04-13 | 2024-07-16 | Nuvalent, Inc. | Amino-substituted heteroaryls for treating cancers with EGFR mutations |
-
0
- GB GB1051218D patent/GB1051218A/en active Active
-
1963
- 1963-03-09 DE DE1470341A patent/DE1470341C3/de not_active Expired
-
1964
- 1964-02-28 CH CH247764A patent/CH438344A/de unknown
- 1964-06-08 FR FR977447A patent/FR3713M/fr active Active
-
1979
- 1979-10-01 IT IT7950418A patent/IT7950418A0/it unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2081471A1 (de) * | 1970-01-30 | 1971-12-03 | Thomae Gmbh Dr K |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1470341B2 (de) | 1973-12-06 |
| FR3713M (fr) | 1965-11-29 |
| GB1051218A (de) | |
| DE1470341A1 (de) | 1969-07-03 |
| IT7950418A0 (it) | 1979-10-01 |
| DE1470341C3 (de) | 1974-07-04 |
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