DE19803528A1 - Verfahren zur Analyse einer Probe mittels eines Elektrochemolumineszenz-Bindungsreaktion-Tests - Google Patents

Verfahren zur Analyse einer Probe mittels eines Elektrochemolumineszenz-Bindungsreaktion-Tests

Info

Publication number
DE19803528A1
DE19803528A1 DE19803528A DE19803528A DE19803528A1 DE 19803528 A1 DE19803528 A1 DE 19803528A1 DE 19803528 A DE19803528 A DE 19803528A DE 19803528 A DE19803528 A DE 19803528A DE 19803528 A1 DE19803528 A1 DE 19803528A1
Authority
DE
Germany
Prior art keywords
potential
working electrode
oxidizing
reducing
dip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19803528A
Other languages
German (de)
English (en)
Inventor
Martin Dr Egger
Gabriele Punzmann
Guenter Dr Mueller
Ursula Pauselius-Fuchs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH, Boehringer Mannheim GmbH filed Critical Roche Diagnostics GmbH
Priority to DE19803528A priority Critical patent/DE19803528A1/de
Priority to JP2000529609A priority patent/JP4388693B2/ja
Priority to PCT/DE1999/000197 priority patent/WO1999039206A1/de
Priority to ES99907282T priority patent/ES2241264T3/es
Priority to DE59911941T priority patent/DE59911941D1/de
Priority to EP99907282A priority patent/EP1051621B1/de
Priority to AT99907282T priority patent/ATE293791T1/de
Priority to US09/600,663 priority patent/US6599473B1/en
Publication of DE19803528A1 publication Critical patent/DE19803528A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DE19803528A 1998-01-30 1998-01-30 Verfahren zur Analyse einer Probe mittels eines Elektrochemolumineszenz-Bindungsreaktion-Tests Withdrawn DE19803528A1 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
DE19803528A DE19803528A1 (de) 1998-01-30 1998-01-30 Verfahren zur Analyse einer Probe mittels eines Elektrochemolumineszenz-Bindungsreaktion-Tests
JP2000529609A JP4388693B2 (ja) 1998-01-30 1999-01-23 電気化学発光結合反応テストを利用したサンプルの分析方法
PCT/DE1999/000197 WO1999039206A1 (de) 1998-01-30 1999-01-23 Verfahren zur analyse einer probe mittels eines elektrochemolumineszenz-bindungsreaktion-tests
ES99907282T ES2241264T3 (es) 1998-01-30 1999-01-23 Metodo para el analisis de una muestra por medio de una prueba de la reaccion de enlace por electroquimiluminiscencia.
DE59911941T DE59911941D1 (de) 1998-01-30 1999-01-23 Verfahren zur analyse einer probe mittels eines elektrochemolumineszenz-bindungsreaktion-tests
EP99907282A EP1051621B1 (de) 1998-01-30 1999-01-23 Verfahren zur analyse einer probe mittels eines elektrochemolumineszenz-bindungsreaktion-tests
AT99907282T ATE293791T1 (de) 1998-01-30 1999-01-23 Verfahren zur analyse einer probe mittels eines elektrochemolumineszenz-bindungsreaktion-tests
US09/600,663 US6599473B1 (en) 1998-01-30 1999-01-23 Electrochemilumiscence method for detecting analytes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803528A DE19803528A1 (de) 1998-01-30 1998-01-30 Verfahren zur Analyse einer Probe mittels eines Elektrochemolumineszenz-Bindungsreaktion-Tests

Publications (1)

Publication Number Publication Date
DE19803528A1 true DE19803528A1 (de) 1999-08-05

Family

ID=7856088

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19803528A Withdrawn DE19803528A1 (de) 1998-01-30 1998-01-30 Verfahren zur Analyse einer Probe mittels eines Elektrochemolumineszenz-Bindungsreaktion-Tests
DE59911941T Expired - Lifetime DE59911941D1 (de) 1998-01-30 1999-01-23 Verfahren zur analyse einer probe mittels eines elektrochemolumineszenz-bindungsreaktion-tests

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59911941T Expired - Lifetime DE59911941D1 (de) 1998-01-30 1999-01-23 Verfahren zur analyse einer probe mittels eines elektrochemolumineszenz-bindungsreaktion-tests

Country Status (7)

Country Link
US (1) US6599473B1 (https=)
EP (1) EP1051621B1 (https=)
JP (1) JP4388693B2 (https=)
AT (1) ATE293791T1 (https=)
DE (2) DE19803528A1 (https=)
ES (1) ES2241264T3 (https=)
WO (1) WO1999039206A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1892524A1 (en) * 2006-08-25 2008-02-27 F. Hoffmann-La Roche AG Cell for conducting electrochemiluminescence measurements

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US6614987B1 (en) * 1998-06-12 2003-09-02 Metabyte, Inc. Television program recording with user preference determination
US8352984B2 (en) 1998-06-12 2013-01-08 Thomson Licensing System and method for generating and managing user preference information for scheduled and stored television programs
US8087051B2 (en) * 2000-06-30 2011-12-27 Thomson Licensing Database management system and method for electronic program guide and television channel lineup organization
US8302127B2 (en) * 2000-09-25 2012-10-30 Thomson Licensing System and method for personalized TV
US8818871B2 (en) 2001-06-21 2014-08-26 Thomson Licensing Method and system for electronic purchases using an intelligent data carrier medium, electronic coupon system, and interactive TV infrastructure
US7641784B2 (en) * 2003-01-30 2010-01-05 Tanita Corporation Method for measuring by means of chemical sensor, and chemical sensor type measuring apparatus
US20100126858A1 (en) * 2003-01-30 2010-05-27 Tanita Corporation Chemical sensor type measuring apparatus
WO2005088291A1 (en) * 2004-03-15 2005-09-22 University Of Saskatchewan Small volume electrochemical analysis system
KR100605536B1 (ko) 2005-02-18 2006-07-28 주식회사 셀텍 광 다이오드 어레이 표면에 전극을 형성하여 이를 이용한전기화학발광반응이 도입된 광 검출 셀 회로를 이용한 유전자 및 단백질 검색장치
US8021529B2 (en) * 2005-04-20 2011-09-20 Thermo Orion, Inc. Ion measurement/calibration cell
ES2675044T3 (es) * 2005-06-03 2018-07-06 Board Of Regents Of The University Of Texas System Electroquímica y quimioluminiscencia electrogenerada con un único electrodo faradaico
BRPI0713206A2 (pt) * 2006-06-30 2012-04-17 Applera Corp métodos de análise das interações das ligações
JP5390021B2 (ja) 2009-07-29 2014-01-15 エフ．ホフマン−ラ ロシュ アーゲー 自動分析器
ES2581553T3 (es) 2010-10-25 2016-09-06 F. Hoffmann-La Roche Ag Utilización de compuestos potenciadores de la señal en la detección electroquimioluminiscente
EP2620764B1 (en) 2012-01-25 2015-11-04 Roche Diagniostics GmbH A luminescence method of detecting an analyte in a liquid sample and analysis system
EP2816345A1 (en) 2013-06-19 2014-12-24 Roche Diagniostics GmbH Electrochemiluminescence method of detecting an analyte in a liquid sample and analysis system
EP3408401B1 (en) 2016-01-29 2019-11-20 Roche Diagnostics GmbH Electrochemiluminescence method and apparatus for detecting an analyte in a liquid sample
ES2974284T3 (es) 2016-03-11 2024-06-26 Roche Diagnostics Gmbh Aminas de cadena ramificada en la detección de electroquimioluminiscencia
WO2019025224A1 (en) 2017-08-01 2019-02-07 Roche Diagnostics Gmbh METHOD OF MONITORING ANALYTE DETECTION OPERATION IN A LIQUID SAMPLE
CN108051586A (zh) * 2017-11-29 2018-05-18 北京美联泰科生物技术有限公司 一种磁微粒化学发光定量检测gfap的试剂盒及其制备方法
CN108037285A (zh) * 2017-11-29 2018-05-15 北京美联泰科生物技术有限公司 一种磁微粒化学发光定量检测uchl-1的试剂盒及其制备方法
CA3192187A1 (en) * 2020-08-21 2022-02-24 Meso Scale Technologies, Llc. Auxiliary electrodes and methods for using and manufacturing the same
CN115480055B (zh) * 2021-09-07 2025-11-18 长沙安赛诊断生物技术有限公司 电化学发光免疫分析试剂盒及其使用方法

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US4917777A (en) * 1986-04-24 1990-04-17 Shipley Company Inc. Method for analyzing additive concentration
CA1339465C (en) * 1986-04-30 1997-09-16 Richard J. Massey Electrochemiluminescent assays
IL90105A (en) 1988-04-29 1993-05-13 Igen Inc Method and apparatus for conducting electro- chemiluminescence measurements
US5068088A (en) 1988-11-03 1991-11-26 Igen, Inc. Method and apparatus for conducting electrochemiluminescent measurements
US5779976A (en) * 1988-11-03 1998-07-14 Igen International, Inc. Apparatus for improved luminescence assays
US5746974A (en) * 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
IL100866A (en) * 1991-02-06 1995-10-31 Igen Inc Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1892524A1 (en) * 2006-08-25 2008-02-27 F. Hoffmann-La Roche AG Cell for conducting electrochemiluminescence measurements
US8940230B2 (en) 2006-08-25 2015-01-27 Roche Diagnostics Operations, Inc. Cell for conducting electrochemiluminescence measurements

Also Published As

Publication number Publication date
WO1999039206A1 (de) 1999-08-05
EP1051621A1 (de) 2000-11-15
DE59911941D1 (de) 2005-05-25
ATE293791T1 (de) 2005-05-15
EP1051621B1 (de) 2005-04-20
JP4388693B2 (ja) 2009-12-24
US6599473B1 (en) 2003-07-29
ES2241264T3 (es) 2005-10-16
JP2002502035A (ja) 2002-01-22

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination