DE19632779A1 - Verfahren und Vorrichtung zum Untersuchen von chemischen Reaktionen in parallel geschalteten, miniaturisierten Reaktoren - Google Patents
Verfahren und Vorrichtung zum Untersuchen von chemischen Reaktionen in parallel geschalteten, miniaturisierten ReaktorenInfo
- Publication number
- DE19632779A1 DE19632779A1 DE19632779A DE19632779A DE19632779A1 DE 19632779 A1 DE19632779 A1 DE 19632779A1 DE 19632779 A DE19632779 A DE 19632779A DE 19632779 A DE19632779 A DE 19632779A DE 19632779 A1 DE19632779 A1 DE 19632779A1
- Authority
- DE
- Germany
- Prior art keywords
- reactors
- reactions
- reaction
- analysis
- parallel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 35
- 238000000034 method Methods 0.000 title claims abstract description 30
- 239000003054 catalyst Substances 0.000 claims abstract description 18
- 239000011541 reaction mixture Substances 0.000 claims abstract description 8
- 238000004611 spectroscopical analysis Methods 0.000 claims abstract description 7
- 230000035484 reaction time Effects 0.000 claims abstract 2
- 229910052751 metal Inorganic materials 0.000 claims description 15
- 239000002184 metal Substances 0.000 claims description 15
- 125000006850 spacer group Chemical group 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 12
- 238000004458 analytical method Methods 0.000 claims description 11
- 238000004566 IR spectroscopy Methods 0.000 claims description 10
- 239000007795 chemical reaction product Substances 0.000 claims description 10
- 239000000047 product Substances 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 4
- 238000011835 investigation Methods 0.000 claims description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
- YZCKVEUIGOORGS-OUBTZVSYSA-N Deuterium Chemical compound [2H] YZCKVEUIGOORGS-OUBTZVSYSA-N 0.000 claims description 3
- 229910052799 carbon Inorganic materials 0.000 claims description 3
- 238000007172 homogeneous catalysis Methods 0.000 claims description 3
- 239000000376 reactant Substances 0.000 claims description 3
- 239000007858 starting material Substances 0.000 claims description 3
- 229910052805 deuterium Inorganic materials 0.000 claims description 2
- 238000007210 heterogeneous catalysis Methods 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 230000005855 radiation Effects 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 238000012216 screening Methods 0.000 abstract description 6
- 239000000126 substance Substances 0.000 abstract description 5
- 230000001960 triggered effect Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 238000005457 optimization Methods 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000001311 chemical methods and process Methods 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 238000000556 factor analysis Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- QVGXLLKOCUKJST-NJFSPNSNSA-N oxygen-18 atom Chemical compound [18O] QVGXLLKOCUKJST-NJFSPNSNSA-N 0.000 description 2
- SBIBMFFZSBJNJF-UHFFFAOYSA-N selenium;zinc Chemical compound [Se]=[Zn] SBIBMFFZSBJNJF-UHFFFAOYSA-N 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 238000005102 attenuated total reflection Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 238000001354 calcination Methods 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000006757 chemical reactions by type Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 238000001307 laser spectroscopy Methods 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000010606 normalization Methods 0.000 description 1
- IOLCXVTUBQKXJR-UHFFFAOYSA-M potassium bromide Inorganic materials [K+].[Br-] IOLCXVTUBQKXJR-UHFFFAOYSA-M 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 238000005245 sintering Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000000870 ultraviolet spectroscopy Methods 0.000 description 1
- 238000001845 vibrational spectrum Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/00745—Inorganic compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/00745—Inorganic compounds
- B01J2219/00747—Catalysts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00835—Comprising catalytically active material
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/08—Methods of screening libraries by measuring catalytic activity
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/18—Libraries containing only inorganic compounds or inorganic materials
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Sampling And Sample Adjustment (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19632779A DE19632779A1 (de) | 1996-08-15 | 1996-08-15 | Verfahren und Vorrichtung zum Untersuchen von chemischen Reaktionen in parallel geschalteten, miniaturisierten Reaktoren |
| AU43796/97A AU731245B2 (en) | 1996-08-15 | 1997-08-12 | Process and apparatus for studying chemical reactions in parallel-connected miniaturized reactors |
| PCT/EP1997/004369 WO1998007026A1 (de) | 1996-08-15 | 1997-08-12 | Verfahren und vorrichtung zum untersuchen von chemischen reaktionen in parallel geschalteten, miniaturisierten reaktoren |
| CA002263212A CA2263212C (en) | 1996-08-15 | 1997-08-12 | Process and apparatus for studying chemical reactions in parallel-connected miniaturized reactors |
| US09/242,199 US6576470B1 (en) | 1996-08-15 | 1997-08-12 | Process and facility for examining chemical reactions in miniaturized reactors arranged parallel to each other |
| DE59712908T DE59712908D1 (de) | 1996-08-15 | 1997-08-12 | Verfahren und vorrichtung zum untersuchen von chemischen reaktionen in parallel geschalteten, miniaturisierten reaktoren |
| EP97941933A EP1012598B1 (de) | 1996-08-15 | 1997-08-12 | Verfahren und vorrichtung zum untersuchen von chemischen reaktionen in parallel geschalteten, miniaturisierten reaktoren |
| JP50828398A JP2001506743A (ja) | 1996-08-15 | 1997-08-12 | 並列接続した小型化反応器内で化学反応を研究するための方法および装置 |
| AT97941933T ATE382859T1 (de) | 1996-08-15 | 1997-08-12 | Verfahren und vorrichtung zum untersuchen von chemischen reaktionen in parallel geschalteten, miniaturisierten reaktoren |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19632779A DE19632779A1 (de) | 1996-08-15 | 1996-08-15 | Verfahren und Vorrichtung zum Untersuchen von chemischen Reaktionen in parallel geschalteten, miniaturisierten Reaktoren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE19632779A1 true DE19632779A1 (de) | 1998-02-19 |
Family
ID=7802628
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19632779A Withdrawn DE19632779A1 (de) | 1996-08-15 | 1996-08-15 | Verfahren und Vorrichtung zum Untersuchen von chemischen Reaktionen in parallel geschalteten, miniaturisierten Reaktoren |
| DE59712908T Revoked DE59712908D1 (de) | 1996-08-15 | 1997-08-12 | Verfahren und vorrichtung zum untersuchen von chemischen reaktionen in parallel geschalteten, miniaturisierten reaktoren |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE59712908T Revoked DE59712908D1 (de) | 1996-08-15 | 1997-08-12 | Verfahren und vorrichtung zum untersuchen von chemischen reaktionen in parallel geschalteten, miniaturisierten reaktoren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6576470B1 (enExample) |
| EP (1) | EP1012598B1 (enExample) |
| JP (1) | JP2001506743A (enExample) |
| AT (1) | ATE382859T1 (enExample) |
| AU (1) | AU731245B2 (enExample) |
| CA (1) | CA2263212C (enExample) |
| DE (2) | DE19632779A1 (enExample) |
| WO (1) | WO1998007026A1 (enExample) |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19830607A1 (de) * | 1998-07-09 | 2000-01-20 | Ferdi Schueth | Verfahren zum Nachweis eines Produktes im Abstrom eines katalytischen Materials einer Vielzahl von katalytischen Materialien |
| DE19952764A1 (de) * | 1998-11-09 | 2000-05-31 | Hewlett Packard Co | Vorrichtung zur Hochdurchsatz-Proben-Verarbeitung, -Analyse und -Sammlung und Verfahren zur Verwendung derselben |
| DE19917433A1 (de) * | 1999-04-19 | 2000-11-16 | Fraunhofer Ges Forschung | Mikroreaktorsystem zum Erzeugen und Testen von Substanzen und Wirkstoffen |
| WO2001005497A1 (en) * | 1999-07-16 | 2001-01-25 | General Electric Company | Method and apparatus for rapid screening of multiphase reactions |
| WO2000015341A3 (de) * | 1998-09-11 | 2001-02-15 | Inst Angewandte Chemie Berlin | Verfahren zur herstellung aktiver und/oder selektiver feststoff-katalysatoren aus anorganischen oder metallorganischen stoffen |
| WO2000051720A3 (en) * | 1999-03-03 | 2001-04-05 | Symyx Technologies Inc | Chemical processing microsystems and methods for preparing and using same |
| EP1129772A3 (en) * | 1999-03-03 | 2001-11-07 | Symyx Technologies, Inc. | Fluid distribution for chemical processing microsystems |
| GB2366793A (en) * | 2000-09-13 | 2002-03-20 | Imperial College | Chemical processing system |
| EP1014087A3 (en) * | 1998-12-25 | 2002-03-27 | JAPAN as represented by DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY | Apparatus for evaluating catalyst performance |
| WO2002004112A3 (en) * | 2000-07-07 | 2002-05-16 | Symyx Technologies Inc | Methods for analysis of heterogeneous catalysts in a multi-variable screening reactor |
| US6737026B1 (en) | 1999-03-03 | 2004-05-18 | Symyx Technologies, Inc. | Methods for identifying and optimizing materials in microfluidic systems |
| WO2004073861A3 (en) * | 2003-02-21 | 2005-01-20 | Stichting Tech Wetenschapp | Microreactor for rapid parallel testing of catalysts |
| US7118917B2 (en) | 2001-03-07 | 2006-10-10 | Symyx Technologies, Inc. | Parallel flow reactor having improved thermal control |
| US7122156B2 (en) | 2000-03-07 | 2006-10-17 | Symyx Technologies, Inc. | Parallel flow reactor having variable composition |
| US7150994B2 (en) | 1999-03-03 | 2006-12-19 | Symyx Technologies, Inc. | Parallel flow process optimization reactor |
| WO2021048375A1 (de) | 2019-09-13 | 2021-03-18 | Hte Gmbh The High Throughput Experimentation Company | Vorrichtung und verfahren zur untersuchung von chemischen prozessen |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7560273B2 (en) * | 2002-07-23 | 2009-07-14 | Applied Biosystems, Llc | Slip cover for heated platen assembly |
| US6536944B1 (en) | 1996-10-09 | 2003-03-25 | Symyx Technologies, Inc. | Parallel screen for rapid thermal characterization of materials |
| WO1998015813A1 (en) * | 1996-10-09 | 1998-04-16 | Symyx Technologies | Infrared spectroscopy and imaging of libraries |
| NO304355B1 (no) | 1997-02-20 | 1998-12-07 | Sinvent As | Multi-autoklav for metodisk, automatisert syntese av zeolitter og andre forbindelser |
| US6149882A (en) | 1998-06-09 | 2000-11-21 | Symyx Technologies, Inc. | Parallel fixed bed reactor and fluid contacting apparatus |
| US6306658B1 (en) | 1998-08-13 | 2001-10-23 | Symyx Technologies | Parallel reactor with internal sensing |
| US6528026B2 (en) | 1998-08-13 | 2003-03-04 | Symyx Technologies, Inc. | Multi-temperature modular reactor and method of using same |
| US6787112B1 (en) | 1998-08-13 | 2004-09-07 | Symyx Technologies, Inc. | Parallel reactor with internal sensing and method of using same |
| US6572828B1 (en) | 1999-07-16 | 2003-06-03 | General Electric Company | Method and apparatus for high-throughput chemical screening |
| US6776963B1 (en) | 1999-12-15 | 2004-08-17 | Uop Llc | Multiple parallel catalytic reactor assembly |
| US6576196B1 (en) | 1999-12-15 | 2003-06-10 | Uop Llc | Multiple parallel catalytic reactor assembly |
| US6627445B1 (en) | 1999-12-15 | 2003-09-30 | Uop Llc | Process for simultaneously evaluating a plurality of catalysts |
| CA2327419C (en) | 1999-12-15 | 2009-01-13 | Uop Llc | Combinatorial catalytic reactor |
| US6368865B1 (en) | 1999-12-15 | 2002-04-09 | Uop Llc | Combinatorial process for performing catalytic chemical reactions |
| DE60044664D1 (de) * | 1999-12-15 | 2010-08-26 | Uop Llc | Kombinatorischer katalytischer Reaktor |
| US6770245B2 (en) | 1999-12-15 | 2004-08-03 | Uop Llc | Multiple parallel processing assembly |
| US6342185B1 (en) | 1999-12-15 | 2002-01-29 | Uop Llc | Combinatorial catalytic reactor |
| US6627571B1 (en) | 2000-03-01 | 2003-09-30 | Symyx Technologies, Inc. | Method and system for the situ synthesis of a combinatorial library of supported catalyst materials |
| DE10012847A1 (de) * | 2000-03-16 | 2001-09-27 | Hte Gmbh | Verfahren und Vorrichtung zur kombinatorischen Herstellung und Testung von Materialbibliotheken durch Anwendung mindestens zweier Analysemethoden |
| DE10019976A1 (de) * | 2000-04-24 | 2001-10-31 | Gwp Ges Fuer Werkstoffpruefung | Vorrichtung und Verfahren zur iterativen Präparation und Testung von katalytisch oder chemisch aktiven Festkörpern |
| US6994827B2 (en) | 2000-06-03 | 2006-02-07 | Symyx Technologies, Inc. | Parallel semicontinuous or continuous reactors |
| US6864091B1 (en) | 2000-08-31 | 2005-03-08 | Symyx Technologies, Inc. | Sampling probe |
| DE10101118C2 (de) * | 2001-01-05 | 2002-12-19 | Inst Angewandte Chemie Berlin | Verfahren zur Bewertung der Leistungsfähigkeit von Feststoffkatalysatoren für ein Reaktionsnetzwerk |
| DE10118782A1 (de) * | 2001-04-18 | 2002-10-31 | Bosch Gmbh Robert | Vorrichtung und Verfahren zur Prüfung eines Materials |
| DE10132252B4 (de) * | 2001-07-04 | 2007-04-19 | Basf Ag | Vorrichtung zur Durchführung von katalytischen Tests |
| US6808685B2 (en) | 2001-09-17 | 2004-10-26 | Uop Llc | Apparatus and method for generating a plurality of isolated effluents |
| US7063982B1 (en) | 2002-03-12 | 2006-06-20 | Uop Llc | Process of vaporizing and reacting a liquid feed |
| US6989131B2 (en) | 2002-03-12 | 2006-01-24 | Uop Llc | Catalytic reactor with integral evaporator |
| US20030173205A1 (en) | 2002-03-12 | 2003-09-18 | Arne Karlsson | Process vessel with integral evaporator |
| DE10242857B4 (de) * | 2002-09-14 | 2005-07-21 | AMTEC-Anwendungszentrum für Mikrotechnologien Chemnitz GmbH | Verfahren und Vorrichtung zur parallelisierten Prüfung von Feststoffen |
| US7256052B2 (en) * | 2002-10-18 | 2007-08-14 | Exxonmobil Chemical Patents Inc. | Chemical reaction and analysis system |
| US7141217B2 (en) * | 2002-12-05 | 2006-11-28 | Uop Llc | Elevated pressure apparatus and method for generating a plurality of isolated effluents |
| EP1649265A1 (en) * | 2003-07-28 | 2006-04-26 | Symyx Technologies, Inc. | Parallel infrared spectroscopy apparatus and method |
| DE10336086A1 (de) * | 2003-08-06 | 2005-03-03 | Hte Ag The High Throughput Experimentation Company | Vorrichtung zur Durchführung von katalytischen Tests |
| DE10348813A1 (de) * | 2003-10-21 | 2005-06-02 | Degussa Ag | Drehrohrofen |
| DE10361003B3 (de) | 2003-12-23 | 2005-07-28 | Hte Ag The High Throughput Experimentation Company | Vorrichtung und Verfahren zur Druck- und Flusskontrolle in Parallelreaktoren |
| WO2008052168A2 (en) | 2006-10-26 | 2008-05-02 | Symyx Technologies, Inc. | High pressure parallel fixed bed reactor and method |
| JP2008224257A (ja) * | 2007-03-09 | 2008-09-25 | Tokyo Electric Power Co Inc:The | 触媒活性評価装置及び評価方法 |
| JP4449997B2 (ja) * | 2007-03-12 | 2010-04-14 | 株式会社日立製作所 | マイクロリアクタシステム |
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| US4099923A (en) * | 1977-01-17 | 1978-07-11 | The Standard Oil Company | Automatic catalytic screening unit |
| US4629903A (en) * | 1984-10-09 | 1986-12-16 | Mobil Oil Corporation | Method of monitoring a catalyst feed and apparatus for implementing the method |
| US5266270A (en) | 1985-06-17 | 1993-11-30 | Institut Francais Du Petrole | On-line test and analysis process and equipment making it possible to establish a material balance of a chemical reaction |
| US6030917A (en) * | 1996-07-23 | 2000-02-29 | Symyx Technologies, Inc. | Combinatorial synthesis and analysis of organometallic compounds and catalysts |
| US5866342A (en) * | 1996-09-27 | 1999-02-02 | Glaxo Group Limited | Systems and methods for the synthesis of organic compounds |
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| JP2001514274A (ja) * | 1997-08-27 | 2001-09-11 | ザ ダウ ケミカル カンパニー | 連続多重反応器を用いるシンジオタクチックビニル芳香族重合 |
| KR100328866B1 (ko) * | 1999-07-02 | 2002-03-20 | 유현식 | 미세유동법을 사용한 스티렌계 중합체의 제조방법 |
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1997
- 1997-08-12 JP JP50828398A patent/JP2001506743A/ja active Pending
- 1997-08-12 WO PCT/EP1997/004369 patent/WO1998007026A1/de not_active Ceased
- 1997-08-12 AU AU43796/97A patent/AU731245B2/en not_active Ceased
- 1997-08-12 AT AT97941933T patent/ATE382859T1/de active
- 1997-08-12 US US09/242,199 patent/US6576470B1/en not_active Expired - Fee Related
- 1997-08-12 CA CA002263212A patent/CA2263212C/en not_active Expired - Fee Related
- 1997-08-12 DE DE59712908T patent/DE59712908D1/de not_active Revoked
- 1997-08-12 EP EP97941933A patent/EP1012598B1/de not_active Revoked
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| US6537500B1 (en) | 1998-07-09 | 2003-03-25 | Hte Aktiengesellschaft | Process for the detection of a product in the discharge of a catalytic material of a plurality of catalytic materials |
| DE19830607C2 (de) * | 1998-07-09 | 2002-08-01 | Hte Ag The High Throughput Exp | Verfahren zum Nachweis eines Produktes im Abstrom eines katalytischen Materials einer Vielzahl von katalytischen Materialien |
| DE19830607A1 (de) * | 1998-07-09 | 2000-01-20 | Ferdi Schueth | Verfahren zum Nachweis eines Produktes im Abstrom eines katalytischen Materials einer Vielzahl von katalytischen Materialien |
| WO2000015341A3 (de) * | 1998-09-11 | 2001-02-15 | Inst Angewandte Chemie Berlin | Verfahren zur herstellung aktiver und/oder selektiver feststoff-katalysatoren aus anorganischen oder metallorganischen stoffen |
| DE19952764A1 (de) * | 1998-11-09 | 2000-05-31 | Hewlett Packard Co | Vorrichtung zur Hochdurchsatz-Proben-Verarbeitung, -Analyse und -Sammlung und Verfahren zur Verwendung derselben |
| DE19952764C2 (de) * | 1998-11-09 | 2003-02-27 | Agilent Technologies Inc | Mikroanalysevorrichtung |
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| EP1014087A3 (en) * | 1998-12-25 | 2002-03-27 | JAPAN as represented by DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY | Apparatus for evaluating catalyst performance |
| EP1129772A3 (en) * | 1999-03-03 | 2001-11-07 | Symyx Technologies, Inc. | Fluid distribution for chemical processing microsystems |
| US6890493B1 (en) | 1999-03-03 | 2005-05-10 | Symyx Technologies, Inc. | Methods and apparatus for fluid distribution in microfluidic systems |
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| US7150994B2 (en) | 1999-03-03 | 2006-12-19 | Symyx Technologies, Inc. | Parallel flow process optimization reactor |
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| US6737026B1 (en) | 1999-03-03 | 2004-05-18 | Symyx Technologies, Inc. | Methods for identifying and optimizing materials in microfluidic systems |
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| DE19917433A1 (de) * | 1999-04-19 | 2000-11-16 | Fraunhofer Ges Forschung | Mikroreaktorsystem zum Erzeugen und Testen von Substanzen und Wirkstoffen |
| DE19917433C2 (de) * | 1999-04-19 | 2003-05-22 | Fraunhofer Ges Forschung | Mikroreaktorsystem zum Erzeugen und Testen von Substanzen und Wirkstoffen |
| WO2001005497A1 (en) * | 1999-07-16 | 2001-01-25 | General Electric Company | Method and apparatus for rapid screening of multiphase reactions |
| US6770482B1 (en) | 1999-07-16 | 2004-08-03 | General Electric | Method and apparatus for rapid screening of multiphase reactions |
| US7122156B2 (en) | 2000-03-07 | 2006-10-17 | Symyx Technologies, Inc. | Parallel flow reactor having variable composition |
| US7111802B2 (en) | 2000-07-07 | 2006-09-26 | Symyx Technologies, Inc. | Apparatus for pressing and other mechanical treatment of materials such as catalysts |
| US6971593B2 (en) | 2000-07-07 | 2005-12-06 | Symyx Technologies, Inc. | Methods for mechanical treatment of materials such as catalysts |
| WO2002004112A3 (en) * | 2000-07-07 | 2002-05-16 | Symyx Technologies Inc | Methods for analysis of heterogeneous catalysts in a multi-variable screening reactor |
| US7503515B2 (en) | 2000-07-07 | 2009-03-17 | Symyx Technologies, Inc. | Methods and apparatus for mechanical treatment of materials such as catalysts |
| GB2366793B (en) * | 2000-09-13 | 2005-03-09 | Imperial College | Chemical processing system and method |
| GB2366793A (en) * | 2000-09-13 | 2002-03-20 | Imperial College | Chemical processing system |
| US7118917B2 (en) | 2001-03-07 | 2006-10-10 | Symyx Technologies, Inc. | Parallel flow reactor having improved thermal control |
| WO2004073861A3 (en) * | 2003-02-21 | 2005-01-20 | Stichting Tech Wetenschapp | Microreactor for rapid parallel testing of catalysts |
| WO2021048375A1 (de) | 2019-09-13 | 2021-03-18 | Hte Gmbh The High Throughput Experimentation Company | Vorrichtung und verfahren zur untersuchung von chemischen prozessen |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1012598B1 (de) | 2008-01-02 |
| DE59712908D1 (de) | 2008-02-14 |
| ATE382859T1 (de) | 2008-01-15 |
| JP2001506743A (ja) | 2001-05-22 |
| WO1998007026A1 (de) | 1998-02-19 |
| AU4379697A (en) | 1998-03-06 |
| EP1012598A1 (de) | 2000-06-28 |
| US6576470B1 (en) | 2003-06-10 |
| AU731245B2 (en) | 2001-03-29 |
| CA2263212A1 (en) | 1998-02-19 |
| CA2263212C (en) | 2006-03-14 |
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