AU731245B2 - Process and apparatus for studying chemical reactions in parallel-connected miniaturized reactors - Google Patents

Process and apparatus for studying chemical reactions in parallel-connected miniaturized reactors Download PDF

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Publication number
AU731245B2
AU731245B2 AU43796/97A AU4379697A AU731245B2 AU 731245 B2 AU731245 B2 AU 731245B2 AU 43796/97 A AU43796/97 A AU 43796/97A AU 4379697 A AU4379697 A AU 4379697A AU 731245 B2 AU731245 B2 AU 731245B2
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AU
Australia
Prior art keywords
reactors
process according
reactions
discharge lines
carried out
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU43796/97A
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English (en)
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AU4379697A (en
Inventor
Hans-Ulrich Hoppe
Christian Miculka
Norbert Windhab
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Evonik Operations GmbH
Original Assignee
Aventis Research and Technologies GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Application filed by Aventis Research and Technologies GmbH and Co KG filed Critical Aventis Research and Technologies GmbH and Co KG
Publication of AU4379697A publication Critical patent/AU4379697A/en
Application granted granted Critical
Publication of AU731245B2 publication Critical patent/AU731245B2/en
Assigned to DEGUSSA A.G. reassignment DEGUSSA A.G. Alteration of Name(s) in Register under S187 Assignors: AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/00745—Inorganic compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/00745—Inorganic compounds
    • B01J2219/00747—Catalysts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00835—Comprising catalytically active material
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/08—Methods of screening libraries by measuring catalytic activity
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/18—Libraries containing only inorganic compounds or inorganic materials
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
AU43796/97A 1996-08-15 1997-08-12 Process and apparatus for studying chemical reactions in parallel-connected miniaturized reactors Ceased AU731245B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19632779 1996-08-15
DE19632779A DE19632779A1 (de) 1996-08-15 1996-08-15 Verfahren und Vorrichtung zum Untersuchen von chemischen Reaktionen in parallel geschalteten, miniaturisierten Reaktoren
PCT/EP1997/004369 WO1998007026A1 (de) 1996-08-15 1997-08-12 Verfahren und vorrichtung zum untersuchen von chemischen reaktionen in parallel geschalteten, miniaturisierten reaktoren

Publications (2)

Publication Number Publication Date
AU4379697A AU4379697A (en) 1998-03-06
AU731245B2 true AU731245B2 (en) 2001-03-29

Family

ID=7802628

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43796/97A Ceased AU731245B2 (en) 1996-08-15 1997-08-12 Process and apparatus for studying chemical reactions in parallel-connected miniaturized reactors

Country Status (8)

Country Link
US (1) US6576470B1 (enExample)
EP (1) EP1012598B1 (enExample)
JP (1) JP2001506743A (enExample)
AT (1) ATE382859T1 (enExample)
AU (1) AU731245B2 (enExample)
CA (1) CA2263212C (enExample)
DE (2) DE19632779A1 (enExample)
WO (1) WO1998007026A1 (enExample)

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DE19830607C2 (de) * 1998-07-09 2002-08-01 Hte Ag The High Throughput Exp Verfahren zum Nachweis eines Produktes im Abstrom eines katalytischen Materials einer Vielzahl von katalytischen Materialien
US6306658B1 (en) 1998-08-13 2001-10-23 Symyx Technologies Parallel reactor with internal sensing
US6528026B2 (en) 1998-08-13 2003-03-04 Symyx Technologies, Inc. Multi-temperature modular reactor and method of using same
US6787112B1 (en) 1998-08-13 2004-09-07 Symyx Technologies, Inc. Parallel reactor with internal sensing and method of using same
DE19843242A1 (de) * 1998-09-11 2000-03-23 Inst Angewandte Chemie Berlin Verfahren zur Herstellung aktiver und/oder selektiver Feststoff-Katalysatoren aus anorganischen oder metallorganischen Feststoffen oder Gemischen davon
US6240790B1 (en) * 1998-11-09 2001-06-05 Agilent Technologies, Inc. Device for high throughout sample processing, analysis and collection, and methods of use thereof
JP3959459B2 (ja) * 1998-12-25 2007-08-15 独立行政法人産業技術総合研究所 触媒性能評価装置
US6749814B1 (en) 1999-03-03 2004-06-15 Symyx Technologies, Inc. Chemical processing microsystems comprising parallel flow microreactors and methods for using same
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US6627445B1 (en) 1999-12-15 2003-09-30 Uop Llc Process for simultaneously evaluating a plurality of catalysts
US6576196B1 (en) 1999-12-15 2003-06-10 Uop Llc Multiple parallel catalytic reactor assembly
ES2347036T3 (es) * 1999-12-15 2010-10-25 Uop Llc Reactor catalitico combinatorio.
US6368865B1 (en) 1999-12-15 2002-04-09 Uop Llc Combinatorial process for performing catalytic chemical reactions
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DE10019976A1 (de) * 2000-04-24 2001-10-31 Gwp Ges Fuer Werkstoffpruefung Vorrichtung und Verfahren zur iterativen Präparation und Testung von katalytisch oder chemisch aktiven Festkörpern
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Also Published As

Publication number Publication date
ATE382859T1 (de) 2008-01-15
DE59712908D1 (de) 2008-02-14
AU4379697A (en) 1998-03-06
CA2263212A1 (en) 1998-02-19
WO1998007026A1 (de) 1998-02-19
CA2263212C (en) 2006-03-14
US6576470B1 (en) 2003-06-10
DE19632779A1 (de) 1998-02-19
EP1012598A1 (de) 2000-06-28
JP2001506743A (ja) 2001-05-22
EP1012598B1 (de) 2008-01-02

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Owner name: DEGUSSA AG

Free format text: FORMER OWNER WAS: AVENTIS RESEARCH AND TECHNOLOGIES GMBH AND CO. KG