DE1930270C3 - Verfahren und Vorrichtung zum Feststellen des Zeitpunkts einer Viskositätsänderung - Google Patents
Verfahren und Vorrichtung zum Feststellen des Zeitpunkts einer ViskositätsänderungInfo
- Publication number
- DE1930270C3 DE1930270C3 DE1930270A DE1930270A DE1930270C3 DE 1930270 C3 DE1930270 C3 DE 1930270C3 DE 1930270 A DE1930270 A DE 1930270A DE 1930270 A DE1930270 A DE 1930270A DE 1930270 C3 DE1930270 C3 DE 1930270C3
- Authority
- DE
- Germany
- Prior art keywords
- magnetic field
- liquid
- container
- ball
- viscosity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title claims description 18
- 239000007788 liquid Substances 0.000 claims description 55
- 230000005291 magnetic effect Effects 0.000 claims description 45
- 238000012360 testing method Methods 0.000 claims description 41
- 230000033001 locomotion Effects 0.000 claims description 25
- 238000010438 heat treatment Methods 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 2
- 238000012544 monitoring process Methods 0.000 claims 1
- 210000004369 blood Anatomy 0.000 description 11
- 239000008280 blood Substances 0.000 description 11
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 9
- 239000001110 calcium chloride Substances 0.000 description 9
- 229910001628 calcium chloride Inorganic materials 0.000 description 9
- 230000015271 coagulation Effects 0.000 description 6
- 238000005345 coagulation Methods 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 238000004804 winding Methods 0.000 description 6
- 238000005259 measurement Methods 0.000 description 5
- 230000023555 blood coagulation Effects 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- PGOHTUIFYSHAQG-LJSDBVFPSA-N (2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amino]hexanoic acid Chemical compound CSCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O PGOHTUIFYSHAQG-LJSDBVFPSA-N 0.000 description 3
- 102000002262 Thromboplastin Human genes 0.000 description 3
- 108010000499 Thromboplastin Proteins 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 238000011835 investigation Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000006116 polymerization reaction Methods 0.000 description 3
- 208000032843 Hemorrhage Diseases 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 239000003990 capacitor Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000005294 ferromagnetic effect Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229910052754 neon Inorganic materials 0.000 description 2
- GKAOGPIIYCISHV-UHFFFAOYSA-N neon atom Chemical compound [Ne] GKAOGPIIYCISHV-UHFFFAOYSA-N 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- 208000019838 Blood disease Diseases 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- 208000031220 Hemophilia Diseases 0.000 description 1
- 208000009292 Hemophilia A Diseases 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 208000014951 hematologic disease Diseases 0.000 description 1
- 208000018706 hematopoietic system disease Diseases 0.000 description 1
- 210000000003 hoof Anatomy 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 230000005499 meniscus Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000012549 training Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
- B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Ecology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73838268A | 1968-06-17 | 1968-06-17 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE1930270A1 DE1930270A1 (de) | 1969-12-18 |
| DE1930270B2 DE1930270B2 (https=) | 1975-04-03 |
| DE1930270C3 true DE1930270C3 (de) | 1975-11-13 |
Family
ID=24967756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE1930270A Expired DE1930270C3 (de) | 1968-06-17 | 1969-06-13 | Verfahren und Vorrichtung zum Feststellen des Zeitpunkts einer Viskositätsänderung |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5014919B1 (https=) |
| BE (1) | BE734598A (https=) |
| DE (1) | DE1930270C3 (https=) |
| FR (1) | FR2011058A1 (https=) |
| GB (1) | GB1235589A (https=) |
| IL (1) | IL32423A (https=) |
| SE (1) | SE366117B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2763299C2 (ru) * | 2017-09-19 | 2021-12-28 | Рено С.А.С | Защитный сильфон для корпуса сцепления автотранспортного средства, поддерживающий соединитель гидролинии рабочего цилиндра сцепления |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5169062U (https=) * | 1974-11-28 | 1976-06-01 | ||
| JPS5312517U (https=) * | 1976-07-15 | 1978-02-02 | ||
| FR2383444A1 (fr) * | 1977-03-11 | 1978-10-06 | Laborgeraete Analysensyst Gmbh | Mesure du temps de coagulation de sang |
| DE3127560C2 (de) * | 1981-07-11 | 1993-01-14 | Jochimsen, Siegfried, 2300 Kiel | Gerät zum Erfassen und Messen der Blutgerinnungszeit mit einem zur Aufnahme der Meßküvette dienenden temperierbaren Metallblock, einer Rühreinrichtung und einer lichtoptischen Trübungsmeßeinrichtung |
| WO1983000228A1 (fr) * | 1981-07-11 | 1983-01-20 | Siegfried Jochimsen | Appareil pour la mesure du temps de coagulation du sang et procede pour saisir et mesurer le temps |
| FR2516658B1 (fr) * | 1981-11-19 | 1987-06-26 | Behnk Holger | Appareil et procede pour detecter et mesurer le temps de coagulation du sang |
| AT375191B (de) * | 1982-08-10 | 1984-07-10 | Foissy Helmut Dipl Ing Dr | Coagulometer zur bestimmung der hitzestabilitaet von milch |
| EP0970742A3 (en) * | 1998-07-09 | 2002-01-23 | Ral Tecnica para el Laboratorio, S.A. | Improved agitator device |
| RU2265204C2 (ru) * | 2003-04-14 | 2005-11-27 | Муниципальное общеообразовательное учреждение лицей № 11 | Вискозиметр |
| WO2006125057A1 (en) * | 2005-05-16 | 2006-11-23 | Haemoscope Corporation | Hemostasis analysis device and method |
| FR3030048B1 (fr) * | 2014-12-15 | 2016-12-23 | Immunodiagnostic Systems France | Procede et dispositif de determination du temps de coagulation d’un echantillon sanguin, et cuvette de reaction |
| KR102773544B1 (ko) * | 2020-05-11 | 2025-02-25 | 현대모비스 주식회사 | 차량용 제동장치 및 그 제어방법 |
-
1969
- 1969-06-04 JP JP44043935A patent/JPS5014919B1/ja active Pending
- 1969-06-13 DE DE1930270A patent/DE1930270C3/de not_active Expired
- 1969-06-16 FR FR6919897A patent/FR2011058A1/fr not_active Withdrawn
- 1969-06-16 SE SE08572/69A patent/SE366117B/xx unknown
- 1969-06-16 BE BE734598D patent/BE734598A/xx unknown
- 1969-06-16 GB GB30360/69A patent/GB1235589A/en not_active Expired
- 1969-06-19 IL IL32423A patent/IL32423A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2763299C2 (ru) * | 2017-09-19 | 2021-12-28 | Рено С.А.С | Защитный сильфон для корпуса сцепления автотранспортного средства, поддерживающий соединитель гидролинии рабочего цилиндра сцепления |
Also Published As
| Publication number | Publication date |
|---|---|
| IL32423A (en) | 1974-09-10 |
| JPS5014919B1 (https=) | 1975-05-31 |
| DE1930270A1 (de) | 1969-12-18 |
| FR2011058A1 (https=) | 1970-02-27 |
| GB1235589A (en) | 1971-06-16 |
| SE366117B (https=) | 1974-04-08 |
| IL32423A0 (en) | 1969-08-27 |
| BE734598A (https=) | 1969-12-01 |
| DE1930270B2 (https=) | 1975-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C3 | Grant after two publication steps (3rd publication) | ||
| E77 | Valid patent as to the heymanns-index 1977 | ||
| EHJ | Ceased/non-payment of the annual fee |