DE1900367A1 - Stabile Glucagonloesung und Verfahren zu ihrer Herstellung - Google Patents

Stabile Glucagonloesung und Verfahren zu ihrer Herstellung

Info

Publication number
DE1900367A1
DE1900367A1 DE19691900367 DE1900367A DE1900367A1 DE 1900367 A1 DE1900367 A1 DE 1900367A1 DE 19691900367 DE19691900367 DE 19691900367 DE 1900367 A DE1900367 A DE 1900367A DE 1900367 A1 DE1900367 A1 DE 1900367A1
Authority
DE
Germany
Prior art keywords
glucagon
solution
months
detergent
solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19691900367
Other languages
German (de)
English (en)
Inventor
Jan Markussen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Terapeutisk Laboratorium AS
Original Assignee
Novo Terapeutisk Laboratorium AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Terapeutisk Laboratorium AS filed Critical Novo Terapeutisk Laboratorium AS
Publication of DE1900367A1 publication Critical patent/DE1900367A1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
DE19691900367 1968-01-10 1969-01-04 Stabile Glucagonloesung und Verfahren zu ihrer Herstellung Pending DE1900367A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0536/68A GB1202607A (en) 1968-01-10 1968-01-10 Improvements in or relating to stable glucagon solutions and their preparation

Publications (1)

Publication Number Publication Date
DE1900367A1 true DE1900367A1 (de) 1969-09-04

Family

ID=9723689

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19691900367 Pending DE1900367A1 (de) 1968-01-10 1969-01-04 Stabile Glucagonloesung und Verfahren zu ihrer Herstellung

Country Status (7)

Country Link
AT (1) AT283600B (un)
BE (1) BE726681A (un)
DE (1) DE1900367A1 (un)
FR (1) FR2000114A1 (un)
GB (1) GB1202607A (un)
IT (1) IT974528B (un)
NL (1) NL6900460A (un)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001185A1 (en) * 1993-06-29 1995-01-12 Ferring B.V. Stabilized pharmaceutical peptide compositions

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458924B2 (en) 1996-08-30 2002-10-01 Novo Nordisk A/S Derivatives of GLP-1 analogs
US6384016B1 (en) * 1998-03-13 2002-05-07 Novo Nordisk A/S Stabilized aqueous peptide solutions
US7235627B2 (en) 1996-08-30 2007-06-26 Novo Nordisk A/S Derivatives of GLP-1 analogs
WO1999047160A1 (en) * 1998-03-13 1999-09-23 Novo Nordisk A/S Stabilized aqueous peptide solutions
US9610329B2 (en) 2009-10-22 2017-04-04 Albireo Pharma, Inc. Stabilized glucagon solutions
EP2490708B1 (en) 2009-10-22 2013-03-27 Biodel Inc. Stabilized glucagon solutions
WO2012059764A1 (en) 2010-11-03 2012-05-10 Arecor Limited Novel composition comprising glucagon
BR112014016889A8 (pt) 2012-01-09 2017-07-04 Adocia composição sob a forma de uma solução aquosa injetável, sujo ph está compreendido entre 6,0 e 8,0 e, formulação de dose unitária com ph compreendido entre 7 e 7,8
US20150314003A2 (en) 2012-08-09 2015-11-05 Adocia Injectable solution at ph 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer
FR3052071B1 (fr) * 2016-06-07 2018-09-07 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon et un co-polyaminoacide
FR3061660B1 (fr) * 2017-01-10 2019-05-31 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide
JP2019517560A (ja) * 2016-06-07 2019-06-24 アドシア ヒトグルカゴン及びコポリアミノ酸を含む注射用溶液の形態の組成物
GB201611077D0 (en) 2016-06-24 2016-08-10 Arecor Ltd Novel composition
FR3074683B1 (fr) * 2017-12-07 2020-01-10 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide
WO2019110838A1 (fr) 2017-12-07 2019-06-13 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide
CN111670042A (zh) 2017-12-07 2020-09-15 阿道恰公司 包含人胰高血糖素和共聚氨基酸的可注射水溶液形式的组合物
FR3083087A1 (fr) 2018-06-29 2020-01-03 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide
CN111683675A (zh) * 2017-12-07 2020-09-18 阿道恰公司 包含人胰高血糖素和共聚氨基酸的呈可注射水溶液形式的组合物
WO2019110837A1 (fr) 2017-12-07 2019-06-13 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide
FR3067247A1 (fr) 2018-06-07 2018-12-14 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2643967A (en) * 1946-08-31 1953-06-30 Wallerstein Co Inc Concentrate of tyrothricin and its therapeutically active components
NL94376C (nl) * 1958-04-28 1960-05-16 Nv Organon Werkwijze ter bereiding van injicieerbare glacagonpreparaten met verlengde werking

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001185A1 (en) * 1993-06-29 1995-01-12 Ferring B.V. Stabilized pharmaceutical peptide compositions
US5482931A (en) * 1993-06-29 1996-01-09 Ferring Ab Stabilized pharmaceutical peptide compositions

Also Published As

Publication number Publication date
IT974528B (it) 1974-07-10
NL6900460A (un) 1969-07-14
AT283600B (de) 1970-08-10
BE726681A (un) 1969-07-09
GB1202607A (en) 1970-08-19
FR2000114A1 (fr) 1969-08-29

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