DE1768273A1 - Neue 3-Oxo-A-nor-B-homo-pregnadiene und ein Verfahren zu deren Herstellung - Google Patents
Neue 3-Oxo-A-nor-B-homo-pregnadiene und ein Verfahren zu deren HerstellungInfo
- Publication number
- DE1768273A1 DE1768273A1 DE19681768273 DE1768273A DE1768273A1 DE 1768273 A1 DE1768273 A1 DE 1768273A1 DE 19681768273 DE19681768273 DE 19681768273 DE 1768273 A DE1768273 A DE 1768273A DE 1768273 A1 DE1768273 A1 DE 1768273A1
- Authority
- DE
- Germany
- Prior art keywords
- group
- homo
- hydrogen atom
- oxo
- represent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims description 34
- 238000002360 preparation method Methods 0.000 title claims description 5
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- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 36
- 150000001875 compounds Chemical class 0.000 claims description 30
- -1 methylenedioxy group Chemical group 0.000 claims description 20
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 13
- 229910052736 halogen Inorganic materials 0.000 claims description 11
- 150000002367 halogens Chemical class 0.000 claims description 11
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- 125000004043 oxo group Chemical group O=* 0.000 claims description 11
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- 239000001257 hydrogen Substances 0.000 claims description 6
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- 125000005530 alkylenedioxy group Chemical group 0.000 claims description 4
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- 235000019271 petrolatum Nutrition 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 238000012746 preparative thin layer chromatography Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 125000006239 protecting group Chemical group 0.000 description 1
- AOJFQRQNPXYVLM-UHFFFAOYSA-N pyridin-1-ium;chloride Chemical compound [Cl-].C1=CC=[NH+]C=C1 AOJFQRQNPXYVLM-UHFFFAOYSA-N 0.000 description 1
- 150000004053 quinones Chemical class 0.000 description 1
- 239000011833 salt mixture Substances 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229910000033 sodium borohydride Inorganic materials 0.000 description 1
- 239000012279 sodium borohydride Substances 0.000 description 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
- 235000010262 sodium metabisulphite Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 229960002317 succinimide Drugs 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 150000003509 tertiary alcohols Chemical class 0.000 description 1
- UGNWTBMOAKPKBL-UHFFFAOYSA-N tetrachloro-1,4-benzoquinone Chemical compound ClC1=C(Cl)C(=O)C(Cl)=C(Cl)C1=O UGNWTBMOAKPKBL-UHFFFAOYSA-N 0.000 description 1
- MUUHXGOJWVMBDY-UHFFFAOYSA-L tetrazolium blue Chemical compound [Cl-].[Cl-].COC1=CC(C=2C=C(OC)C(=CC=2)[N+]=2N(N=C(N=2)C=2C=CC=CC=2)C=2C=CC=CC=2)=CC=C1[N+]1=NC(C=2C=CC=CC=2)=NN1C1=CC=CC=C1 MUUHXGOJWVMBDY-UHFFFAOYSA-L 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J69/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by contraction of only one ring by one atom and expansion of only one ring by one atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH644167A CH532562A (de) | 1967-05-03 | 1967-05-03 | Verfahren zur Herstellung neuer 3-Oxo-A-nor-B-homo-pregnatriene |
| CH644067A CH529735A (de) | 1967-05-03 | 1967-05-03 | Verfahren zur Herstellung neuer 3-Oxo-A-nor-B-homopregnadiene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1768273A1 true DE1768273A1 (de) | 1971-04-22 |
Family
ID=25699576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19681768273 Pending DE1768273A1 (de) | 1967-05-03 | 1968-04-24 | Neue 3-Oxo-A-nor-B-homo-pregnadiene und ein Verfahren zu deren Herstellung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3625997A (en:Method) |
| BE (1) | BE714558A (en:Method) |
| CH (2) | CH532562A (en:Method) |
| DE (1) | DE1768273A1 (en:Method) |
| FR (2) | FR1588479A (en:Method) |
| GB (1) | GB1205101A (en:Method) |
| NL (1) | NL6806233A (en:Method) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5272169A (en) * | 1992-03-27 | 1993-12-21 | The Dupont Merck Pharmaceutical Company | (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories |
| US5217983A (en) * | 1992-03-27 | 1993-06-08 | Du Pont Merck Pharmaceutical Company | (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1370565A (fr) * | 1961-06-19 | 1964-08-28 | Roussel Uclaf | Nouveaux a-nor b-homo stéroïdes et leur procédé d'obtention |
| GB1047343A (en:Method) * | 1963-02-27 |
-
1967
- 1967-05-03 CH CH644167A patent/CH532562A/de not_active IP Right Cessation
- 1967-05-03 CH CH644067A patent/CH529735A/de not_active IP Right Cessation
-
1968
- 1968-04-24 DE DE19681768273 patent/DE1768273A1/de active Pending
- 1968-04-29 US US725182A patent/US3625997A/en not_active Expired - Lifetime
- 1968-04-30 FR FR1588479D patent/FR1588479A/fr not_active Expired
- 1968-04-30 GB GB20376/68A patent/GB1205101A/en not_active Expired
- 1968-05-02 NL NL6806233A patent/NL6806233A/xx unknown
- 1968-05-02 BE BE714558D patent/BE714558A/xx unknown
- 1968-07-25 FR FR160578A patent/FR7943M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1205101A (en) | 1970-09-16 |
| FR1588479A (en:Method) | 1970-04-17 |
| FR7943M (en:Method) | 1970-05-25 |
| CH532562A (de) | 1973-01-15 |
| CH529735A (de) | 1972-10-31 |
| NL6806233A (en:Method) | 1968-11-04 |
| US3625997A (en) | 1971-12-07 |
| BE714558A (en:Method) | 1968-11-04 |
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