DE1695412A1 - Verfahren zur Herstellung von Ribonucleosid-Verbindungen - Google Patents

Verfahren zur Herstellung von Ribonucleosid-Verbindungen

Info

Publication number
DE1695412A1
DE1695412A1 DE19661695412 DE1695412A DE1695412A1 DE 1695412 A1 DE1695412 A1 DE 1695412A1 DE 19661695412 DE19661695412 DE 19661695412 DE 1695412 A DE1695412 A DE 1695412A DE 1695412 A1 DE1695412 A1 DE 1695412A1
Authority
DE
Germany
Prior art keywords
compound
preparation
compounds
trityl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19661695412
Other languages
German (de)
English (en)
Inventor
Tsung-Ying Shen
Ruyle William Vance
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1695412A1 publication Critical patent/DE1695412A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19661695412 1965-04-01 1966-03-31 Verfahren zur Herstellung von Ribonucleosid-Verbindungen Pending DE1695412A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US444808A US3322747A (en) 1965-04-01 1965-04-01 Thionocarbonate nucleosides

Publications (1)

Publication Number Publication Date
DE1695412A1 true DE1695412A1 (de) 1971-04-15

Family

ID=23766442

Family Applications (3)

Application Number Title Priority Date Filing Date
DE19661595989 Pending DE1595989A1 (de) 1965-04-01 1966-03-31 Ribonucleoside und Verfahren zu deren Herstellung
DE19661695445 Pending DE1695445A1 (de) 1965-04-01 1966-03-31 Verfahren zur Herstellung von Ribonucleosid-Verbindungen
DE19661695412 Pending DE1695412A1 (de) 1965-04-01 1966-03-31 Verfahren zur Herstellung von Ribonucleosid-Verbindungen

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE19661595989 Pending DE1595989A1 (de) 1965-04-01 1966-03-31 Ribonucleoside und Verfahren zu deren Herstellung
DE19661695445 Pending DE1695445A1 (de) 1965-04-01 1966-03-31 Verfahren zur Herstellung von Ribonucleosid-Verbindungen

Country Status (6)

Country Link
US (1) US3322747A (OSRAM)
CH (1) CH482688A (OSRAM)
DE (3) DE1595989A1 (OSRAM)
FR (1) FR1482902A (OSRAM)
GB (3) GB1111988A (OSRAM)
NL (1) NL6604388A (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3463850A (en) * 1967-01-03 1969-08-26 Merck & Co Inc Arabinofuranosyl 2-thiopyrimidines and pharmaceutical compositions thereof
SE391183B (sv) * 1971-04-15 1977-02-07 Asahi Chemical Ind 2',3'-0-sulfinylcytidin och syraadditionssalter derav till anvendning som mellanprodukt for framstellning av 2,2'-anhydro-(1-beta-d-arabinofuranosyl) cytosin
JPS535311B2 (OSRAM) * 1974-01-30 1978-02-25
US4112221A (en) * 1974-07-17 1978-09-05 Asahi Kasei Kogyo Kabushiki Kaisha Process for preparing 8,2'-O-anhydropurine nucleosides
JPS5176297A (en) * 1974-12-27 1976-07-01 Asahi Chemical Ind 2*2**anhidoroshichijin 5** rinsanesuterunoseizohoho
US4978655A (en) * 1986-12-17 1990-12-18 Yale University Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses
US5212294A (en) * 1988-03-24 1993-05-18 Bristol-Myers Squibb Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides
US4904770A (en) * 1988-03-24 1990-02-27 Bristol-Myers Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides
EP0342422A3 (en) * 1988-05-16 1990-12-05 F. Hoffmann-La Roche Ag Process for the preparation of 2',3'-dideoxynucleosides, and intermediates used therein
JPH02104586A (ja) * 1988-06-21 1990-04-17 Moses Nam Fong Lee ピリミジン誘導体及びその使用
US5008384A (en) * 1988-07-12 1991-04-16 Pfizer Inc. Process for the production of O.sup. 2,2'-anhydro-1-(β-D-arabinofuranosyl)thymine
FI922014A0 (fi) * 1989-11-06 1992-05-05 Nycomed As Nukleosidderivat.
JP2526414B2 (ja) * 1994-05-20 1996-08-21 工業技術院長 制ガン剤エステル化合物及びその製造方法
CN101765369A (zh) * 2007-03-19 2010-06-30 俄勒冈州由俄勒冈州立大学代表州高等教育委员会行使 曼尼希碱n-氧化物药物

Also Published As

Publication number Publication date
GB1111990A (en) 1968-05-01
CH482688A (de) 1969-12-15
US3322747A (en) 1967-05-30
GB1111988A (en) 1968-05-01
NL6604388A (OSRAM) 1966-10-03
DE1695445A1 (de) 1971-04-15
GB1111989A (en) 1968-05-01
DE1595989A1 (de) 1970-03-19
FR1482902A (fr) 1967-06-02

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