DE1668876B2 - N-acyl geschuetzte aminosaeuren und peptide, verfahren zu ihrer herstellung und ihre verwendung bei peptidsynthesen - Google Patents

N-acyl geschuetzte aminosaeuren und peptide, verfahren zu ihrer herstellung und ihre verwendung bei peptidsynthesen

Info

Publication number
DE1668876B2
DE1668876B2 DE1968C0044387 DEC0044387A DE1668876B2 DE 1668876 B2 DE1668876 B2 DE 1668876B2 DE 1968C0044387 DE1968C0044387 DE 1968C0044387 DE C0044387 A DEC0044387 A DE C0044387A DE 1668876 B2 DE1668876 B2 DE 1668876B2
Authority
DE
Germany
Prior art keywords
solution
group
biphenylyl
acid
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE1968C0044387
Other languages
German (de)
English (en)
Other versions
DE1668876A1 (de
Inventor
Beat Dr. Riehen; Sieber Peter Reinach; Basel Iselin (Schweiz)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH107367A external-priority patent/CH509266A/de
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE1668876A1 publication Critical patent/DE1668876A1/de
Publication of DE1668876B2 publication Critical patent/DE1668876B2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE1968C0044387 1967-01-25 1968-01-16 N-acyl geschuetzte aminosaeuren und peptide, verfahren zu ihrer herstellung und ihre verwendung bei peptidsynthesen Granted DE1668876B2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH107367A CH509266A (de) 1967-01-25 1967-01-25 Verfahren zum Schützen von freien Aminogruppen in aminosäuren oder Peptiden oder deren Derivaten
CH1203867 1967-08-28
CH1710867 1967-12-06

Publications (2)

Publication Number Publication Date
DE1668876A1 DE1668876A1 (de) 1971-06-03
DE1668876B2 true DE1668876B2 (de) 1976-11-11

Family

ID=27172672

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1968C0044387 Granted DE1668876B2 (de) 1967-01-25 1968-01-16 N-acyl geschuetzte aminosaeuren und peptide, verfahren zu ihrer herstellung und ihre verwendung bei peptidsynthesen
DE19681793827 Pending DE1793827A1 (de) 1967-01-25 1968-01-16 Neue aminoschutzgruppen, ihre verwendung bei peptidsynthesen und verfahren zur herstellung der entsprechend geschuetzten aminosaeuren und peptide

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19681793827 Pending DE1793827A1 (de) 1967-01-25 1968-01-16 Neue aminoschutzgruppen, ihre verwendung bei peptidsynthesen und verfahren zur herstellung der entsprechend geschuetzten aminosaeuren und peptide

Country Status (4)

Country Link
DE (2) DE1668876B2 (xx)
FR (1) FR1554051A (xx)
GB (1) GB1218251A (xx)
NL (1) NL6801063A (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5216801A (en) 2000-03-16 2001-09-24 Hoffmann La Roche Carboxylic acid derivatives as ip antagonists

Also Published As

Publication number Publication date
NL6801063A (xx) 1968-07-26
DE1668876A1 (de) 1971-06-03
GB1218251A (en) 1971-01-06
DE1793827A1 (de) 1976-05-13
FR1554051A (xx) 1969-01-17

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977
EHV Ceased/renunciation