DE1620156A1 - Verfahren zur Herstellung von neuen Dibenzocycloheptatrienderivaten - Google Patents
Verfahren zur Herstellung von neuen DibenzocycloheptatrienderivatenInfo
- Publication number
- DE1620156A1 DE1620156A1 DE19651620156 DE1620156A DE1620156A1 DE 1620156 A1 DE1620156 A1 DE 1620156A1 DE 19651620156 DE19651620156 DE 19651620156 DE 1620156 A DE1620156 A DE 1620156A DE 1620156 A1 DE1620156 A1 DE 1620156A1
- Authority
- DE
- Germany
- Prior art keywords
- ecm
- total
- ether
- solution
- washed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/64—Acyl halides
- C07C57/74—Acyl halides containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/39—Unsaturated compounds containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Secondary Cells (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR976650A FR1488211A (fr) | 1964-06-01 | 1964-06-01 | Nouveaux dérivés du dibenzocycloheptatriène et leur préparation |
| FR993217A FR89653E (fr) | 1964-06-01 | 1964-10-29 | Nouveaux dérivés du dibenzocycloheptatriène et leur préparation |
| FR14253A FR89659E (fr) | 1964-06-01 | 1965-04-22 | Nouveaux dérivés du dibenzocycloheptatriène et leur préparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1620156A1 true DE1620156A1 (de) | 1970-01-02 |
Family
ID=27242107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19651620156 Pending DE1620156A1 (de) | 1964-06-01 | 1965-06-01 | Verfahren zur Herstellung von neuen Dibenzocycloheptatrienderivaten |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3480624A (enExample) |
| BE (1) | BE664609A (enExample) |
| BR (1) | BR6570074D0 (enExample) |
| CH (2) | CH448071A (enExample) |
| DE (1) | DE1620156A1 (enExample) |
| DK (2) | DK119253B (enExample) |
| ES (2) | ES313645A1 (enExample) |
| FI (1) | FI42324B (enExample) |
| FR (5) | FR1488211A (enExample) |
| GB (1) | GB1109847A (enExample) |
| IL (1) | IL23643A (enExample) |
| LU (1) | LU48732A1 (enExample) |
| NL (1) | NL6506574A (enExample) |
| NO (1) | NO120632B (enExample) |
| SE (1) | SE312549B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3907999A (en) * | 1968-01-30 | 1975-09-23 | Merck & Co Inc | Substituted dibenzocyclooctene compositions |
| US3911017A (en) * | 1969-04-04 | 1975-10-07 | Sandoz Ag | 5-Aminomethyl-5H-dibenzo{8 a,d{9 cycloheptenes |
| CH532038A (de) * | 1970-05-25 | 1972-12-31 | Ciba Geigy Ag | Verfahren zur Herstellung von neuen Cycloheptenderivaten |
| US3951983A (en) * | 1970-11-10 | 1976-04-20 | Pfizer Inc. | Phenoxypropanolpiperazines |
| US4082801A (en) * | 1972-11-27 | 1978-04-04 | Merck & Co., Inc. | 4-Aminomethyldibenzobicyclo[5.1.0]octanes |
| DE2704934A1 (de) * | 1976-02-17 | 1977-08-18 | Sandoz Ag | Organische verbindungen, ihre herstellung und verwendung |
| DE3248094C1 (de) * | 1982-12-24 | 1984-06-14 | Gödecke AG, 1000 Berlin | 7H-Dibenzo(a,c)cyclohepten-5-on(7)-Derivate,Verfahren zu deren Herstellung und deren Verwendung bei der Bekaempfung psychischer Erkrankungen und von Magen-und/oder Darmgeschwueren |
| MY113463A (en) * | 1994-01-04 | 2002-03-30 | Novo Nordisk As | Novel heterocyclic compounds |
| DE19547625A1 (de) * | 1995-02-15 | 1996-08-22 | Media Tech Vertriebs Gmbh | Kolbenmaschine |
| US5698551A (en) * | 1995-04-07 | 1997-12-16 | Novo Nordisk A/S | Heterocyclic compounds |
| US6323206B1 (en) | 1996-07-12 | 2001-11-27 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| JP2000516210A (ja) | 1996-07-12 | 2000-12-05 | ロイコサイト,インコーポレーテッド | ケモカインレセプターアンタゴニストとその使用方法 |
| US6613905B1 (en) | 1998-01-21 | 2003-09-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6509346B2 (en) | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| DK1049700T3 (da) | 1998-01-21 | 2006-02-20 | Millennium Pharm Inc | Kemokinreceptorantagonister og fremgangsmåder til anvendelse deraf |
| WO1999037619A1 (en) | 1998-01-21 | 1999-07-29 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US7271176B2 (en) | 1998-09-04 | 2007-09-18 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use thereof |
| US7541365B2 (en) | 2001-11-21 | 2009-06-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| TWI291467B (en) | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3073847A (en) * | 1959-02-12 | 1963-01-15 | Hoffmann La Roche | 9-(3-amino-1-propynyl) derivatives of 9-xanthenols and 9-thioxanthenols and a process for their preparation |
| US3100207A (en) * | 1959-07-08 | 1963-08-06 | Smith Kline French Lab | 10-aminoalkylbenzo[b,f]thiepin and -dibenz[b,f]oxepin derivatives |
| BE638839A (enExample) * | 1962-10-19 |
-
0
- BE BE664609D patent/BE664609A/xx unknown
- FR FR145D patent/FR145F/fr active Active
-
1964
- 1964-06-01 FR FR976650A patent/FR1488211A/fr not_active Expired
- 1964-08-13 FR FR985144A patent/FR4069M/fr not_active Expired
- 1964-10-29 FR FR993217A patent/FR89653E/fr not_active Expired
-
1965
- 1965-04-22 FR FR14253A patent/FR89659E/fr not_active Expired
- 1965-05-24 NL NL6506574A patent/NL6506574A/xx unknown
- 1965-05-28 US US459921A patent/US3480624A/en not_active Expired - Lifetime
- 1965-05-31 BR BR170074/65A patent/BR6570074D0/pt unknown
- 1965-05-31 IL IL23643A patent/IL23643A/xx unknown
- 1965-05-31 DK DK274065AA patent/DK119253B/da unknown
- 1965-05-31 SE SE7095/65A patent/SE312549B/xx unknown
- 1965-05-31 LU LU48732A patent/LU48732A1/xx unknown
- 1965-06-01 FI FI1310/65A patent/FI42324B/fi active
- 1965-06-01 NO NO158324A patent/NO120632B/no unknown
- 1965-06-01 CH CH83567A patent/CH448071A/fr unknown
- 1965-06-01 CH CH759465A patent/CH436269A/fr unknown
- 1965-06-01 DE DE19651620156 patent/DE1620156A1/de active Pending
- 1965-06-01 GB GB23386/65A patent/GB1109847A/en not_active Expired
- 1965-06-01 ES ES0313645A patent/ES313645A1/es not_active Expired
- 1965-08-02 ES ES0316050A patent/ES316050A1/es not_active Expired
-
1966
- 1966-07-28 DK DK393966AA patent/DK115988B/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL23643A (en) | 1969-02-27 |
| SE312549B (enExample) | 1969-07-21 |
| US3480624A (en) | 1969-11-25 |
| LU48732A1 (enExample) | 1965-08-02 |
| ES313645A1 (es) | 1966-03-01 |
| FR4069M (enExample) | 1966-04-12 |
| BE664609A (enExample) | |
| DK115988B (da) | 1969-12-01 |
| BR6570074D0 (pt) | 1973-09-11 |
| FR145F (enExample) | |
| NO120632B (enExample) | 1970-11-16 |
| FI42324B (enExample) | 1970-03-31 |
| FR89653E (fr) | 1967-07-28 |
| NL6506574A (enExample) | 1965-12-02 |
| CH436269A (fr) | 1967-05-31 |
| FR89659E (fr) | 1967-07-28 |
| GB1109847A (en) | 1968-04-18 |
| DK119253B (da) | 1970-12-07 |
| CH448071A (fr) | 1967-12-15 |
| ES316050A1 (es) | 1965-12-01 |
| FR1488211A (fr) | 1967-07-13 |
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