DE1592217C3 - Verfahren zur Herstellung von pharmazeutischem Bismuthylnitrat - Google Patents
Verfahren zur Herstellung von pharmazeutischem BismuthylnitratInfo
- Publication number
- DE1592217C3 DE1592217C3 DE19661592217 DE1592217A DE1592217C3 DE 1592217 C3 DE1592217 C3 DE 1592217C3 DE 19661592217 DE19661592217 DE 19661592217 DE 1592217 A DE1592217 A DE 1592217A DE 1592217 C3 DE1592217 C3 DE 1592217C3
- Authority
- DE
- Germany
- Prior art keywords
- nitrate
- bismuth
- electrolyte
- pharmaceutical
- subnitrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QGWDKKHSDXWPET-UHFFFAOYSA-E pentabismuth;oxygen(2-);nonahydroxide;tetranitrate Chemical compound [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-2].[Bi+3].[Bi+3].[Bi+3].[Bi+3].[Bi+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O QGWDKKHSDXWPET-UHFFFAOYSA-E 0.000 title claims description 28
- 238000000034 method Methods 0.000 title claims description 23
- 238000004519 manufacturing process Methods 0.000 title claims description 10
- 229910052797 bismuth Inorganic materials 0.000 claims description 20
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 claims description 20
- 229910002651 NO3 Inorganic materials 0.000 claims description 14
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 claims description 14
- 239000003792 electrolyte Substances 0.000 claims description 14
- 229910017604 nitric acid Inorganic materials 0.000 claims description 14
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 claims description 13
- 238000005868 electrolysis reaction Methods 0.000 claims description 10
- 230000002378 acidificating effect Effects 0.000 claims description 5
- 239000007864 aqueous solution Substances 0.000 claims description 4
- 238000004090 dissolution Methods 0.000 claims description 4
- 229910001959 inorganic nitrate Inorganic materials 0.000 claims description 4
- PAWQVTBBRAZDMG-UHFFFAOYSA-N 2-(3-bromo-2-fluorophenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC(Br)=C1F PAWQVTBBRAZDMG-UHFFFAOYSA-N 0.000 claims description 2
- 239000003513 alkali Substances 0.000 claims 1
- 229960001482 bismuth subnitrate Drugs 0.000 description 17
- 238000006243 chemical reaction Methods 0.000 description 11
- 239000000047 product Substances 0.000 description 9
- 239000007788 liquid Substances 0.000 description 8
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 8
- VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Chemical compound [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 description 8
- 230000007062 hydrolysis Effects 0.000 description 7
- 238000006460 hydrolysis reaction Methods 0.000 description 7
- 239000002244 precipitate Substances 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 239000007789 gas Substances 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 235000010344 sodium nitrate Nutrition 0.000 description 4
- 239000004317 sodium nitrate Substances 0.000 description 4
- 239000002253 acid Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 229910021529 ammonia Inorganic materials 0.000 description 2
- PPNKDDZCLDMRHS-UHFFFAOYSA-N dinitrooxybismuthanyl nitrate Chemical compound [Bi+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O PPNKDDZCLDMRHS-UHFFFAOYSA-N 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000036571 hydration Effects 0.000 description 2
- 238000006703 hydration reaction Methods 0.000 description 2
- -1 hydroxyl ions Chemical class 0.000 description 2
- GQPLMRYTRLFLPF-UHFFFAOYSA-N nitrous oxide Inorganic materials [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 2
- KJFMBFZCATUALV-UHFFFAOYSA-N phenolphthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C(=O)O1 KJFMBFZCATUALV-UHFFFAOYSA-N 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 229910015902 Bi 2 O 3 Inorganic materials 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229910001963 alkali metal nitrate Inorganic materials 0.000 description 1
- 229910001451 bismuth ion Inorganic materials 0.000 description 1
- WMWLMWRWZQELOS-UHFFFAOYSA-N bismuth(III) oxide Inorganic materials O=[Bi]O[Bi]=O WMWLMWRWZQELOS-UHFFFAOYSA-N 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- IQPNAANSBPBGFQ-UHFFFAOYSA-N luteolin Chemical compound C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(O)C(O)=C1 IQPNAANSBPBGFQ-UHFFFAOYSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- 229940082615 organic nitrates used in cardiac disease Drugs 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B1/00—Electrolytic production of inorganic compounds or non-metals
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G29/00—Compounds of bismuth
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Materials Engineering (AREA)
- Metallurgy (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Electrolytic Production Of Metals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL6508499A NL6508499A (enExample) | 1965-07-01 | 1965-07-01 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE1592217A1 DE1592217A1 (de) | 1970-07-16 |
| DE1592217B2 DE1592217B2 (de) | 1971-01-21 |
| DE1592217C3 true DE1592217C3 (de) | 1974-11-07 |
Family
ID=19793540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19661592217 Expired DE1592217C3 (de) | 1965-07-01 | 1966-06-30 | Verfahren zur Herstellung von pharmazeutischem Bismuthylnitrat |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE1592217C3 (enExample) |
| GB (1) | GB1079410A (enExample) |
| NL (2) | NL6508499A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1298634C (zh) * | 2004-07-22 | 2007-02-07 | 中国地质大学（武汉） | 微乳液法制备纳米碱式硝酸铋的方法 |
-
0
- NL NL130170D patent/NL130170C/xx active
-
1965
- 1965-07-01 NL NL6508499A patent/NL6508499A/xx unknown
-
1966
- 1966-06-29 GB GB2922066A patent/GB1079410A/en not_active Expired
- 1966-06-30 DE DE19661592217 patent/DE1592217C3/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1592217B2 (de) | 1971-01-21 |
| NL130170C (enExample) | |
| NL6508499A (enExample) | 1967-01-02 |
| DE1592217A1 (de) | 1970-07-16 |
| GB1079410A (en) | 1967-08-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0158910B1 (de) | Verfahren zur Rückgewinnung von Kupfer aus einer ammoniakalischen Kupfer-Ätzlösung und Rekonditionierung derselben | |
| DE2940186A1 (de) | Verfahren zur herstellung von nitriten | |
| DE2321417A1 (de) | Verfahren zur elektrolyse und elektrolytische zelle zu dessen durchfuehrung | |
| DE2833939A1 (de) | Verfahren und vorrichtung zur herstellung von metallfolien durch elektrolytische abscheidung | |
| EP0599136B1 (de) | Verfahren zur Herstellung von reinem Nickelhydroxid sowie dessen Verwendung | |
| DE2941450C2 (de) | Verfahren zur wirtschaftlichen Herstellung von Titandioxid | |
| DE69014755T2 (de) | Verfahren zur Herstellung von elektrolytischem Blei und von elementarem Schwefel aus Galenit. | |
| DE1301587B (de) | Verfahren und Vorrichtung zur elektrolytischen Abscheidung von Kupferpulver | |
| DE2713236C3 (enExample) | ||
| DE2240731C3 (de) | Verfahren zur Herstellung von Glyoxylsäure | |
| DE2539137A1 (de) | Verfahren zur elektrolytischen gewinnung von nickel und zink sowie elektrolysezelle hierfuer | |
| DE2011610C3 (de) | Verfahren zur Gewinnung eines Metalls aus einer Spuren des Metallions enthaltenden Lösung mittels Elektrolyse | |
| DE2908592B2 (de) | Verfahren zur Abtrennung und Gewinnung eines chalcophilen Elements aus einer wäßrigen Lösung | |
| DE1592217C3 (de) | Verfahren zur Herstellung von pharmazeutischem Bismuthylnitrat | |
| DE2607512A1 (de) | Verfahren zur herstellung eines metallpulvers | |
| DE2924143C2 (de) | Verfahren zum galvanischen Abscheiden von Metall | |
| DE69206797T2 (de) | Elektrolytischer entsilberungsprozess | |
| DE2929305C2 (de) | Verfahren und Vorrichtung zur kontinuierlichen galvanischen Abscheidung von Mangan auf Stahl | |
| EP0445516B1 (de) | Verfahren und Vorrichtung zum Erzeugen von Silbernitrat | |
| DE2456058C2 (de) | Verfahren und Anordnung zum mit dem Eisenbeizen verbundenen im Kreislauf oder chargenweise durchgeführten Aufarbeiten von Beizendlösungen | |
| DE2060066B2 (de) | Verfahren zur Herstellung von Magnesiumhydroxid und Chlorgas durch Elektrolyse von wäßrigen Elektrolyten, die in der Hauptmenge Magnesiumchlorid sowie Alkalichlorid gelöst enthalten | |
| DE1592441C3 (enExample) | ||
| DE2602031B1 (de) | Verfahren zur herstellung von zinnii-sulfat | |
| DE2706432A1 (de) | Verfahren zur auslaugung von metall-legierungen, metallgemischen oder erzen | |
| DE69044C (de) | Verfahren zur Darstellung von Bleiweifs |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C3 | Grant after two publication steps (3rd publication) | ||
| E77 | Valid patent as to the heymanns-index 1977 | ||
| 8339 | Ceased/non-payment of the annual fee |