DE1296631B - Verfahren zur Herstellung von 16-Fluormethylen-steroiden - Google Patents

Verfahren zur Herstellung von 16-Fluormethylen-steroiden

Info

Publication number
DE1296631B
DE1296631B DEM56495A DEM0056495A DE1296631B DE 1296631 B DE1296631 B DE 1296631B DE M56495 A DEM56495 A DE M56495A DE M0056495 A DEM0056495 A DE M0056495A DE 1296631 B DE1296631 B DE 1296631B
Authority
DE
Germany
Prior art keywords
acid
oxido
steroids
fluoromethyl
fluoromethylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DEM56495A
Other languages
German (de)
English (en)
Inventor
Bork
Dipl-Chem Dr Fritz
Dr Hans-Guenther
Dipl-Chem Dr Karl-Heinz
Kraft
Von Werder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck KGaA
Original Assignee
E Merck AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E Merck AG filed Critical E Merck AG
Priority to DEM56495A priority Critical patent/DE1296631B/de
Priority to CH64564A priority patent/CH460758A/de
Priority to NL6401411A priority patent/NL6401411A/xx
Priority to BR15794164A priority patent/BR6457941D0/pt
Priority to DK174464A priority patent/DK112381B/da
Publication of DE1296631B publication Critical patent/DE1296631B/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
DEM56495A 1962-05-21 1963-04-13 Verfahren zur Herstellung von 16-Fluormethylen-steroiden Pending DE1296631B (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DEM56495A DE1296631B (de) 1963-04-13 1963-04-13 Verfahren zur Herstellung von 16-Fluormethylen-steroiden
CH64564A CH460758A (de) 1962-05-21 1964-01-21 Verfahren zur Herstellung von 16-Fluormethylen-steroiden
NL6401411A NL6401411A (xx) 1963-04-13 1964-02-17
BR15794164A BR6457941D0 (pt) 1963-04-13 1964-03-30 Processo para a preparacao de 16-fluormetileno-esteroides
DK174464A DK112381B (da) 1963-04-13 1964-04-08 Fremgangsmåde til fremstilling af 16-fluormethylen-17α-hydroxy-20-keto-steroider af pregnan-, 19-nor-pregnan- eller iso-pregnanrækken eller 17α-estere deraf.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEM56495A DE1296631B (de) 1963-04-13 1963-04-13 Verfahren zur Herstellung von 16-Fluormethylen-steroiden

Publications (1)

Publication Number Publication Date
DE1296631B true DE1296631B (de) 1969-06-04

Family

ID=7308637

Family Applications (1)

Application Number Title Priority Date Filing Date
DEM56495A Pending DE1296631B (de) 1962-05-21 1963-04-13 Verfahren zur Herstellung von 16-Fluormethylen-steroiden

Country Status (4)

Country Link
BR (1) BR6457941D0 (xx)
DE (1) DE1296631B (xx)
DK (1) DK112381B (xx)
NL (1) NL6401411A (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2104970A1 (xx) * 1970-09-11 1972-04-28 Ciba Geigy Ag

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2104970A1 (xx) * 1970-09-11 1972-04-28 Ciba Geigy Ag

Also Published As

Publication number Publication date
NL6401411A (xx) 1964-11-25
BR6457941D0 (pt) 1973-07-17
DK112381B (da) 1968-12-09

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