DE112018000658B4 - Stark hydrophobe bewuchshemmende Beschichtungen für implantierbare medizinische Vorrichtungen - Google Patents

Stark hydrophobe bewuchshemmende Beschichtungen für implantierbare medizinische Vorrichtungen Download PDF

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Publication number
DE112018000658B4
DE112018000658B4 DE112018000658.1T DE112018000658T DE112018000658B4 DE 112018000658 B4 DE112018000658 B4 DE 112018000658B4 DE 112018000658 T DE112018000658 T DE 112018000658T DE 112018000658 B4 DE112018000658 B4 DE 112018000658B4
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solution
polymer
organocatalyzed
polythioether
coating
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German (de)
English (en)
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DE112018000658T5 (de
Inventor
Amos Cahan
James Hedrick
Mareva FEVRE
Nathaniel Park
Rudy Wojtecki
Theodore Van Kessel
Yi Yan Yang
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Agency for Science Technology and Research Singapore
International Business Machines Corp
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Agency for Science Technology and Research Singapore
International Business Machines Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/52—Polythioethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G75/00—Macromolecular compounds obtained by reactions forming a linkage containing sulfur with or without nitrogen, oxygen, or carbon in the main chain of the macromolecule
    • C08G75/02—Polythioethers
    • C08G75/0204—Polyarylenethioethers
    • C08G75/0209—Polyarylenethioethers derived from monomers containing one aromatic ring
    • C08G75/0213—Polyarylenethioethers derived from monomers containing one aromatic ring containing elements other than carbon, hydrogen or sulfur
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G75/00—Macromolecular compounds obtained by reactions forming a linkage containing sulfur with or without nitrogen, oxygen, or carbon in the main chain of the macromolecule
    • C08G75/02—Polythioethers
    • C08G75/0204—Polyarylenethioethers
    • C08G75/0227—Polyarylenethioethers derived from monomers containing two or more aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G75/00—Macromolecular compounds obtained by reactions forming a linkage containing sulfur with or without nitrogen, oxygen, or carbon in the main chain of the macromolecule
    • C08G75/02—Polythioethers
    • C08G75/04—Polythioethers from mercapto compounds or metallic derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G75/00—Macromolecular compounds obtained by reactions forming a linkage containing sulfur with or without nitrogen, oxygen, or carbon in the main chain of the macromolecule
    • C08G75/20—Polysulfones
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D181/00—Coating compositions based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing sulfur, with or without nitrogen, oxygen, or carbon only; Coating compositions based on polysulfones; Coating compositions based on derivatives of such polymers
    • C09D181/02—Polythioethers; Polythioether-ethers
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D181/00—Coating compositions based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing sulfur, with or without nitrogen, oxygen, or carbon only; Coating compositions based on polysulfones; Coating compositions based on derivatives of such polymers
    • C09D181/06—Polysulfones; Polyethersulfones
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Paints Or Removers (AREA)
  • Materials For Medical Uses (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
DE112018000658.1T 2017-04-25 2018-04-20 Stark hydrophobe bewuchshemmende Beschichtungen für implantierbare medizinische Vorrichtungen Active DE112018000658B4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15/496,473 US10507267B2 (en) 2017-04-25 2017-04-25 Highly hydrophobic antifouling coatings for implantable medical devices
US15/496,473 2017-04-25
PCT/IB2018/052764 WO2018198003A1 (en) 2017-04-25 2018-04-20 Highly hydrophobic antifouling coatings for implantable medical devices

Publications (2)

Publication Number Publication Date
DE112018000658T5 DE112018000658T5 (de) 2019-10-31
DE112018000658B4 true DE112018000658B4 (de) 2020-02-20

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US (2) US10507267B2 (enExample)
JP (1) JP7083459B2 (enExample)
CN (1) CN110573191B (enExample)
DE (1) DE112018000658B4 (enExample)
GB (1) GB2576277B (enExample)
WO (1) WO2018198003A1 (enExample)

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Publication number Priority date Publication date Assignee Title
US10563069B2 (en) 2017-03-30 2020-02-18 International Business Machines Corporation Prevention of biofilm formation
US10507267B2 (en) 2017-04-25 2019-12-17 International Business Machines Corporation Highly hydrophobic antifouling coatings for implantable medical devices
US10745586B2 (en) 2017-08-08 2020-08-18 International Business Machines Corporation Fluorinated networks for anti-fouling surfaces
US10696849B2 (en) 2017-08-08 2020-06-30 International Business Machines Corporation Tailorable surface topology for antifouling coatings

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697402A (en) 1971-06-25 1972-10-10 Grace W R & Co Photocurable liquid polyene-polythiol polymer composition
SE456347B (sv) 1982-02-09 1988-09-26 Ird Biomaterial Ab Ytmodifierat fast substrat samt forfarande for framstellning derav
JPH07116296B2 (ja) * 1987-04-30 1995-12-13 東洋紡績株式会社 ポリスルフィド樹脂の製造方法
DE3738277A1 (de) * 1987-11-11 1989-05-24 Bayer Ag Verfahren zur herstellung von polyarylensulfiden
GB8813395D0 (en) 1988-06-07 1988-07-13 Elliott T S J Medical devices
US5213898A (en) 1989-10-12 1993-05-25 Norsk Hydro A.S. Process for the preparation of surface modified solid substrates
WO2001029118A1 (en) 1999-10-19 2001-04-26 Commonwealth Scientific And Industrial Research Organisation Preparation of functional polymeric surface
US9089407B2 (en) 2001-04-23 2015-07-28 Massachusetts Institute Of Technology Antibacterial coatings that inhibit biofilm formation on implants
FR2878248B1 (fr) 2004-11-22 2007-01-12 Surfactis Technologies Soc Par Composes bisphosphoniques pour empecher ou limiter la fixation de macromolecules, de microorganismes et d'un biofilm sur des surfaces solides, notamment metallique ou minerales
US9084546B2 (en) 2005-08-31 2015-07-21 The Regents Of The University Of Michigan Co-electrodeposited hydrogel-conducting polymer electrodes for biomedical applications
US8944804B2 (en) 2006-01-04 2015-02-03 Liquidia Technologies, Inc. Nanostructured surfaces for biomedical/biomaterial applications and processes thereof
US20090010980A1 (en) 2006-10-12 2009-01-08 Alok Singh Materials coatings and methods for self-cleaning and self-decontamination of metal surface
US7708908B2 (en) 2007-02-28 2010-05-04 The Regents Of The University Of Michigan Carboxylic acid-modified EDOT for bioconjugation
JP2008238711A (ja) 2007-03-28 2008-10-09 Fujifilm Corp 親水性部材及び下塗り組成物
US8168297B2 (en) 2007-04-23 2012-05-01 E. I. Du Pont De Nemours And Company Fluoropolymer coated film, process for forming the same, and fluoropolymer liquid composition
US7985881B2 (en) 2007-09-12 2011-07-26 Guard Products Llc Aromatic imine compounds for use as sulfide scavengers
NZ588865A (en) 2008-04-30 2012-05-25 Xyleco Inc Processing biomass
GB0818074D0 (en) 2008-10-02 2008-11-05 Lytix Biopharma As Treatment of biofilms
US9333163B2 (en) 2008-10-06 2016-05-10 Massachusetts Institute Of Technology Particles with multiple functionalized surface domains
US20120058355A1 (en) 2009-06-02 2012-03-08 Hyomin Lee Coatings
EP2289971A1 (en) 2009-08-27 2011-03-02 Total Petrochemicals Research Feluy Ring opening polymerisation of cyclic carbonates with organic catalyst systems
US20110171279A1 (en) 2009-11-02 2011-07-14 Ndsu Research Foundation Polyethylenimine biocides
EP2611474A1 (en) 2010-06-03 2013-07-10 Capsulution Pharma AG Coating of a drug-eluting medical device
GB2481644A (en) 2010-07-02 2012-01-04 Cambridge Display Tech Ltd A method of forming an organic thin film transistor
WO2012009239A2 (en) 2010-07-13 2012-01-19 The University Of Houston System Sensors and separation based on molecular recognition via electropolymerization and colloidal layer templates
JP6109144B2 (ja) 2011-03-28 2017-04-05 スリーエム イノベイティブ プロパティズ カンパニー 硬化性組成物、物品、硬化方法及びタックフリー反応生成物
CN103889562B (zh) 2011-05-27 2017-09-08 康奈尔大学 纳米粒子官能化的膜及其制备方法和用途
CA2837726C (en) 2011-06-20 2016-09-20 Sri International Electrochemical disinfection of implanted catheters
RU2602250C2 (ru) 2011-08-31 2016-11-10 Селф-Саспендинг Проппант Ллс Самосуспендирующиеся проппанты для гидравлического разрыва пласта
US9839213B2 (en) 2011-10-14 2017-12-12 The University Of Georgia Research Foundation, Inc. Photochemical cross-linkable polymers, methods of making photochemical cross-linkable polymers, methods of using photochemical cross-linkable polymers, and methods of making articles containing photochemical cross-linkable polymers
CA2860934A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Modification of surfaces for fluid and solid repellency
BR112014020021B1 (pt) 2012-02-20 2020-12-15 Basf Se Composição, método para melhorar a atividade antimicrobiana de um biocida, e, usos de uma poliamina e de uma composição
US9018172B2 (en) 2012-09-26 2015-04-28 Massachusetts Institute Of Technology Modification of peptides via SNAr reactions of thiols with fluorinated aromatics
US9508806B2 (en) 2012-09-28 2016-11-29 Sony Corporation Electronic device, image display device and sensor, and method for manufacturing electronic device
US9109140B2 (en) * 2013-01-22 2015-08-18 Xerox Corporation Mixed organosiloxane networks for tunable surface properties for blanket substrates for indirect printing methods
SG11201505823PA (en) 2013-01-30 2015-08-28 Agency Science Tech & Res Method for improved stability of layer-by-layer assemblies for marine antifouling performance with a novel polymer
WO2014152423A1 (en) 2013-03-15 2014-09-25 Bard Access Systems, Inc. Antithrombic coatings and uses thereof
CN105102386A (zh) 2013-03-15 2015-11-25 肖特玻璃科技(苏州)有限公司 化学钢化的柔性超薄玻璃
US9701931B2 (en) 2013-09-30 2017-07-11 Chemlink Laboratories, Llc Environmentally preferred antimicrobial compositions
CN103709186B (zh) * 2013-12-27 2016-08-17 烟台德邦先进硅材料有限公司 聚氟硅氧烷制备的防污氟硅涂料及其应用
US9399044B2 (en) 2014-05-28 2016-07-26 International Business Machines Corporation Antimicrobial cationic polyamines
SG11201703038VA (en) * 2014-10-14 2017-05-30 Agency Science Tech & Res Antibacterial and/or antifouling polymers
WO2016176548A1 (en) * 2015-04-29 2016-11-03 3M Innovative Properties Company Composition including a polythiol and a polyepoxide and methods relating to the composition
CN105288584A (zh) * 2015-11-24 2016-02-03 东南大学 一种智能抗菌多肽涂层的制备方法
US9862802B2 (en) 2015-11-30 2018-01-09 International Business Machines Corporation Poly(thioaminal) probe based lithography
CN109451742A (zh) 2016-06-30 2019-03-08 3M创新有限公司 包含多硫醇、不饱和化合物、光引发剂和有机氢过氧化物的可双重固化的硫醇-烯组合物以及在航空航天中使用的由其制备的交联聚合物密封剂
US20190313642A1 (en) 2016-11-15 2019-10-17 Albert-Ludwigs-Universität Freiburg A simultaneously antimicrobial and protein-repellent polyzwitterion
JP7418211B2 (ja) 2016-12-14 2024-01-19 エコラブ ユーエスエイ インク 四級カチオン性ポリマー
US10563069B2 (en) 2017-03-30 2020-02-18 International Business Machines Corporation Prevention of biofilm formation
US10507267B2 (en) 2017-04-25 2019-12-17 International Business Machines Corporation Highly hydrophobic antifouling coatings for implantable medical devices
US10745586B2 (en) 2017-08-08 2020-08-18 International Business Machines Corporation Fluorinated networks for anti-fouling surfaces
US10696849B2 (en) 2017-08-08 2020-06-30 International Business Machines Corporation Tailorable surface topology for antifouling coatings

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
(1) Park, N. et al., „Organocatalyzed synthesis of fluorinated poly(aryl thioethers)", Nature Communications 8:166 August 2017, S.1-7 *

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