DE102011001550A1 - Vorrichtung zum Fördern und Mischen von Mikromengen an Reagenzien und zur Durchführung chemischer Reaktionen - Google Patents

Vorrichtung zum Fördern und Mischen von Mikromengen an Reagenzien und zur Durchführung chemischer Reaktionen Download PDF

Info

Publication number
DE102011001550A1
DE102011001550A1 DE102011001550A DE102011001550A DE102011001550A1 DE 102011001550 A1 DE102011001550 A1 DE 102011001550A1 DE 102011001550 A DE102011001550 A DE 102011001550A DE 102011001550 A DE102011001550 A DE 102011001550A DE 102011001550 A1 DE102011001550 A1 DE 102011001550A1
Authority
DE
Germany
Prior art keywords
reservoir
reaction cell
reagent reservoir
chamber
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102011001550A
Other languages
German (de)
English (en)
Inventor
Gerhard Hartwich
Norbert Persike
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Friz Biochem Gesellschaft fuer Bioanalytik mbH
Original Assignee
Friz Biochem Gesellschaft fuer Bioanalytik mbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Friz Biochem Gesellschaft fuer Bioanalytik mbH filed Critical Friz Biochem Gesellschaft fuer Bioanalytik mbH
Priority to DE102011001550A priority Critical patent/DE102011001550A1/de
Publication of DE102011001550A1 publication Critical patent/DE102011001550A1/de
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/65—Mixers with shaking, oscillating, or vibrating mechanisms the materials to be mixed being directly submitted to a pulsating movement, e.g. by means of an oscillating piston or air column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B01L7/5255—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones by moving sample containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00891—Feeding or evacuation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00952—Sensing operations
    • B01J2219/00954—Measured properties
    • B01J2219/00957—Compositions or concentrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE102011001550A 2011-03-25 2011-03-25 Vorrichtung zum Fördern und Mischen von Mikromengen an Reagenzien und zur Durchführung chemischer Reaktionen Withdrawn DE102011001550A1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE102011001550A DE102011001550A1 (de) 2011-03-25 2011-03-25 Vorrichtung zum Fördern und Mischen von Mikromengen an Reagenzien und zur Durchführung chemischer Reaktionen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102011001550A DE102011001550A1 (de) 2011-03-25 2011-03-25 Vorrichtung zum Fördern und Mischen von Mikromengen an Reagenzien und zur Durchführung chemischer Reaktionen

Publications (1)

Publication Number Publication Date
DE102011001550A1 true DE102011001550A1 (de) 2012-09-27

Family

ID=46831430

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102011001550A Withdrawn DE102011001550A1 (de) 2011-03-25 2011-03-25 Vorrichtung zum Fördern und Mischen von Mikromengen an Reagenzien und zur Durchführung chemischer Reaktionen

Country Status (1)

Country Link
DE (1) DE102011001550A1 (un)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2500658A (en) * 2012-03-28 2013-10-02 Dna Electronics Ltd Biosensor device and system
GB2543834A (en) * 2015-10-30 2017-05-03 Intelligent Energy Ltd Hydrogen generator system
CN115151816A (zh) * 2019-11-27 2022-10-04 沃特世科技公司 梯度比例阀

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000703A1 (en) * 1984-07-06 1986-01-30 Metrohm Ag Device and method for quantitative and/or qualitative determination of liquids
DD245773A3 (de) * 1984-09-26 1987-05-20 Akad Wissenschaften Ddr Speicher- und reaktionszelle
DE10109589A1 (de) 2001-02-28 2002-09-12 Merck Patent Gmbh Mikroreaktor
DE10261158A1 (de) * 2002-12-20 2004-07-15 Biochip Technologies Gmbh Vorrichtung zum Aufbringen von Mikrotröpfchen auf ein Trägersubstrat
DE102004051394A1 (de) 2004-10-21 2006-04-27 Advalytix Ag Verfahren zur Bewegung von kleinen Flüssigkeitsmengen in Mikrokanälen und Mikrokanalsystem
DE60116326T2 (de) * 2000-08-03 2006-07-13 Arrayjet Ltd., Mayfield Hochparallele herstellung von mikroarrays mittels tintenstrahldruckkopf
DE60023862T2 (de) * 1999-03-29 2006-07-27 ECOLE POLYTECHNIQUE FéDéRALE DE LAUSANNE Mikromassstabgetreue vorrichtung für chemische analyse
DE60216748T2 (de) * 2001-05-09 2007-10-25 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Flüssigkeitspumpsystem
DE102008021364A1 (de) * 2008-04-29 2009-06-25 Siemens Aktiengesellschaft Verfahren zum Einbringen von Trockenreagenzien in eine Analyseeinheit und Kit
DE102008042581A1 (de) * 2008-10-02 2010-04-08 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Mikrofluidische Extraktions- und Reaktionsvorrichtung
EP1510255B1 (en) * 2003-08-29 2010-11-10 Syrris Limited A microfluidic system

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000703A1 (en) * 1984-07-06 1986-01-30 Metrohm Ag Device and method for quantitative and/or qualitative determination of liquids
DD245773A3 (de) * 1984-09-26 1987-05-20 Akad Wissenschaften Ddr Speicher- und reaktionszelle
DE60023862T2 (de) * 1999-03-29 2006-07-27 ECOLE POLYTECHNIQUE FéDéRALE DE LAUSANNE Mikromassstabgetreue vorrichtung für chemische analyse
DE60116326T2 (de) * 2000-08-03 2006-07-13 Arrayjet Ltd., Mayfield Hochparallele herstellung von mikroarrays mittels tintenstrahldruckkopf
DE10109589A1 (de) 2001-02-28 2002-09-12 Merck Patent Gmbh Mikroreaktor
DE60216748T2 (de) * 2001-05-09 2007-10-25 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Flüssigkeitspumpsystem
DE10261158A1 (de) * 2002-12-20 2004-07-15 Biochip Technologies Gmbh Vorrichtung zum Aufbringen von Mikrotröpfchen auf ein Trägersubstrat
EP1510255B1 (en) * 2003-08-29 2010-11-10 Syrris Limited A microfluidic system
DE102004051394A1 (de) 2004-10-21 2006-04-27 Advalytix Ag Verfahren zur Bewegung von kleinen Flüssigkeitsmengen in Mikrokanälen und Mikrokanalsystem
DE102008021364A1 (de) * 2008-04-29 2009-06-25 Siemens Aktiengesellschaft Verfahren zum Einbringen von Trockenreagenzien in eine Analyseeinheit und Kit
DE102008042581A1 (de) * 2008-10-02 2010-04-08 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Mikrofluidische Extraktions- und Reaktionsvorrichtung

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2500658A (en) * 2012-03-28 2013-10-02 Dna Electronics Ltd Biosensor device and system
US9739743B2 (en) 2012-03-28 2017-08-22 Dnae Group Holdings Limited Biosensor device and system
US10527574B2 (en) 2012-03-28 2020-01-07 Dnae Group Holdings Limited Biosensor device and system
GB2543834A (en) * 2015-10-30 2017-05-03 Intelligent Energy Ltd Hydrogen generator system
CN115151816A (zh) * 2019-11-27 2022-10-04 沃特世科技公司 梯度比例阀
US11940424B2 (en) 2019-11-27 2024-03-26 Waters Technologies Corporation Gradient proportioning valve

Similar Documents

Publication Publication Date Title
DE112013003342B4 (de) Patrone zur biochemischen Verwendung und biochemische Verarbeitungsvorrichtung
EP3120929B1 (de) Einlassventil für kammersysteme und probenbhälter sowie kammersysteme und probenbehälter mit derartigen einlassventilen
Kaminski et al. Controlled droplet microfluidic systems for multistep chemical and biological assays
DE102006002258B4 (de) Modul zur Aufbereitung einer biologischen Probe, Biochip-Satz und Verwendung des Moduls
EP2227330B1 (de) Mobiles schnelltestsystem für die nukleinsäureanalytik
EP1081233B1 (de) Probenkammer zur Flüssigkeitsbehandlung biologischer Proben
DE60036277T2 (de) Testgerät zur durchführung von nukleinsäure-amplifikationsreaktionen
DE10149684B4 (de) Vorrichtung zur Halterung eines Substanzbibliothekenträgers
DE60201257T2 (de) Verfahren und vorrichtung zur kontinuerlichen durchführung einer biologischen, chemischen oder biochemischen reaktion
DE102010015161A1 (de) Mikrofluidiksystem und Verfahren zu dessen Betreiben
DE102011001550A1 (de) Vorrichtung zum Fördern und Mischen von Mikromengen an Reagenzien und zur Durchführung chemischer Reaktionen
DE102016222032A1 (de) Mikrofluidische Vorrichtung und Verfahren zur Analyse von Nukleinsäuren
DE102009001257A1 (de) Vorrichtung und Verfahren zur Handhabung von Flüssigkeiten
EP2337633B1 (de) Vorrichtung zur durchführung einer pcr
EP2156890B1 (de) Anordnung und Verfahren zum Erzeugen, Manipulieren und Analysieren von Kompartimenten
EP3609617B1 (de) Vorrichtung zur prozessierung einer flüssigen probe
WO2010040758A1 (de) Vorrichtung und verfahren zur ausführung mehrerer paralleler pcr-reaktionen im durchflussverfahren
EP1521635A1 (de) Vorrichtung zur handhabung von flüssigkeiten in einer mehrzahl von kanälen
EP3609995B1 (de) Verfahren zum prozessieren einer flüssigen probe
DE102006010959A1 (de) Vorrichtung zum Nachweis biochemischer Zielmoleküle und Verfahren zur Herstellung der Vorrichtung
EP3094740B1 (de) Analyseeinheit zum durchführen einer verschachtelten polymerasekettenreaktion, analysevorrichtung, verfahren zum betreiben einer solchen analyseeinheit und verfahren zum herstellen einer solchen analyseeinheit
DE19922285A1 (de) Probengefäß
DE102004050139B4 (de) Mikrofluidprozessor und Verfahren zur Durchführung einer Polymerasekettenreaktion
WO2004103564A1 (de) Vorrichtung und verfahren zum positionieren und ausschleusen von in separationsmedium eingebetteten fluidkompartimenten
WO2019096562A1 (de) Adapter für eine mikrofluidische vorrichtung zur überführung einer substanz, insbesondere einer probe

Legal Events

Date Code Title Description
R012 Request for examination validly filed
R016 Response to examination communication
R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee