DE102005018389A1 - Azolderivate als Inhibitoren von Lipasen und Phospholipasen - Google Patents

Azolderivate als Inhibitoren von Lipasen und Phospholipasen Download PDF

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Publication number
DE102005018389A1
DE102005018389A1 DE102005018389A DE102005018389A DE102005018389A1 DE 102005018389 A1 DE102005018389 A1 DE 102005018389A1 DE 102005018389 A DE102005018389 A DE 102005018389A DE 102005018389 A DE102005018389 A DE 102005018389A DE 102005018389 A1 DE102005018389 A1 DE 102005018389A1
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DE
Germany
Prior art keywords
alkyl
formula
compounds
halogen
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102005018389A
Other languages
German (de)
English (en)
Inventor
Gerhard Dr. Zoller
Stefan Dr. Petry
Günter Dr. Müller
Hubert Dr. Heuer
Norbert Dr. Tennagels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36694158&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE102005018389(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Priority to DE102005018389A priority Critical patent/DE102005018389A1/de
Priority to PCT/EP2006/003411 priority patent/WO2006111321A1/de
Priority to KR1020077024150A priority patent/KR20080004501A/ko
Priority to MX2007012732A priority patent/MX2007012732A/es
Priority to JP2008506977A priority patent/JP2008536884A/ja
Priority to BRPI0608495-8A priority patent/BRPI0608495A2/pt
Priority to CNA2006800127294A priority patent/CN101160293A/zh
Priority to RU2007142657/04A priority patent/RU2414458C2/ru
Priority to CA002606301A priority patent/CA2606301A1/en
Priority to EP06761897A priority patent/EP1874741A1/de
Priority to NZ562694A priority patent/NZ562694A/en
Priority to AU2006237127A priority patent/AU2006237127A1/en
Priority to ARP060101521A priority patent/AR053228A1/es
Priority to TW095113710A priority patent/TW200722421A/zh
Priority to MYPI20061785A priority patent/MY142441A/en
Publication of DE102005018389A1 publication Critical patent/DE102005018389A1/de
Priority to ZA200707929A priority patent/ZA200707929B/xx
Priority to MA30299A priority patent/MA29393B1/fr
Priority to IL186635A priority patent/IL186635A0/en
Priority to US11/873,846 priority patent/US8921404B2/en
Priority to NO20075938A priority patent/NO20075938L/no
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE102005018389A 2005-04-20 2005-04-20 Azolderivate als Inhibitoren von Lipasen und Phospholipasen Withdrawn DE102005018389A1 (de)

Priority Applications (20)

Application Number Priority Date Filing Date Title
DE102005018389A DE102005018389A1 (de) 2005-04-20 2005-04-20 Azolderivate als Inhibitoren von Lipasen und Phospholipasen
AU2006237127A AU2006237127A1 (en) 2005-04-20 2006-04-13 Azole derivatives in the form of Lipase and Phospholipase inhibitors
NZ562694A NZ562694A (en) 2005-04-20 2006-04-13 Isothiazole and isoxazole derivatives in the form of lipase and phospholipase inhibitors
KR1020077024150A KR20080004501A (ko) 2005-04-20 2006-04-13 리파제 및 포스포리파제 억제제 형태의 아졸 유도체
MX2007012732A MX2007012732A (es) 2005-04-20 2006-04-13 Derivados de azol en forma de inhibidores de lipasas y fosfolipasas.
JP2008506977A JP2008536884A (ja) 2005-04-20 2006-04-13 リパーゼ及びホスホリパーゼの阻害剤の形態のアゾール誘導体
BRPI0608495-8A BRPI0608495A2 (pt) 2005-04-20 2006-04-13 derivados de azol na forma de inibidores de lipase e fosfolipase
CNA2006800127294A CN101160293A (zh) 2005-04-20 2006-04-13 脂酶和磷脂酶抑制剂形式的吡咯衍生物
RU2007142657/04A RU2414458C2 (ru) 2005-04-20 2006-04-13 Производные азола в качестве ингибиторов липаз и фосфолипаз
CA002606301A CA2606301A1 (en) 2005-04-20 2006-04-13 Azole derivatives in the form of lipase and phospholipase inhibitors
EP06761897A EP1874741A1 (de) 2005-04-20 2006-04-13 Azolderivate als inhibitoren von lipasen und phospholipasen
PCT/EP2006/003411 WO2006111321A1 (de) 2005-04-20 2006-04-13 Azolderivate als inhibitoren von lipasen und phospholipasen
TW095113710A TW200722421A (en) 2005-04-20 2006-04-18 Azole derivatives as inhibitors of lipases and phospholipases
ARP060101521A AR053228A1 (es) 2005-04-20 2006-04-18 Derivados de azol en calidad de inibidores de lipasas y fosfolipasas
MYPI20061785A MY142441A (en) 2005-04-20 2006-04-19 Azole derivatives as inhibitors of lipases and phospholipases
ZA200707929A ZA200707929B (en) 2005-04-20 2007-09-17 Azole derivatives in the form of lipase and phospholipase inhibitors
MA30299A MA29393B1 (fr) 2005-04-20 2007-10-12 Derives d'azole sous forme d'inhibiteurs de lipase et de phospholipase
IL186635A IL186635A0 (en) 2005-04-20 2007-10-14 Azole derivatives in the form of lipase and phospholipase inhibitors
US11/873,846 US8921404B2 (en) 2005-04-20 2007-10-17 Azole derivatives in the form of lipase and phospholipase inhibitors
NO20075938A NO20075938L (no) 2005-04-20 2007-11-19 Azolderivater i form av lipase og fosforfaseinhibitorer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005018389A DE102005018389A1 (de) 2005-04-20 2005-04-20 Azolderivate als Inhibitoren von Lipasen und Phospholipasen

Publications (1)

Publication Number Publication Date
DE102005018389A1 true DE102005018389A1 (de) 2006-10-26

Family

ID=36694158

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102005018389A Withdrawn DE102005018389A1 (de) 2005-04-20 2005-04-20 Azolderivate als Inhibitoren von Lipasen und Phospholipasen

Country Status (20)

Country Link
US (1) US8921404B2 (https=)
EP (1) EP1874741A1 (https=)
JP (1) JP2008536884A (https=)
KR (1) KR20080004501A (https=)
CN (1) CN101160293A (https=)
AR (1) AR053228A1 (https=)
AU (1) AU2006237127A1 (https=)
BR (1) BRPI0608495A2 (https=)
CA (1) CA2606301A1 (https=)
DE (1) DE102005018389A1 (https=)
IL (1) IL186635A0 (https=)
MA (1) MA29393B1 (https=)
MX (1) MX2007012732A (https=)
MY (1) MY142441A (https=)
NO (1) NO20075938L (https=)
NZ (1) NZ562694A (https=)
RU (1) RU2414458C2 (https=)
TW (1) TW200722421A (https=)
WO (1) WO2006111321A1 (https=)
ZA (1) ZA200707929B (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010500300A (ja) 2006-08-08 2010-01-07 サノフィ−アベンティス アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用
CN101657435A (zh) 2007-04-05 2010-02-24 塞诺菲-安万特股份有限公司 作为脂肪酶和磷酯酶抑制剂的5-氧代异唑类化合物
NZ580127A (en) 2007-04-05 2011-03-31 Sanofi Aventis Imidazolidine carboxamide derivatives as lipase and phospholipase inhibitors
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2010003624A2 (en) 2008-07-09 2010-01-14 Sanofi-Aventis Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010044441A1 (ja) 2008-10-17 2010-04-22 塩野義製薬株式会社 血管内皮リパーゼ阻害活性を有する酢酸アミド誘導体
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
GB2466121B (en) * 2008-12-15 2010-12-08 Amira Pharmaceuticals Inc Antagonists of lysophosphatidic acid receptors
MX2012001729A (es) 2009-08-26 2012-06-13 Sanofi Sa Nuevos hidratos cristalinos de fluoroglicosido heteroaromatico, productos farmaceuticos que comprenden estos compuestos, y su empleo.
CN102753545A (zh) 2009-12-15 2012-10-24 盐野义制药株式会社 具有血管内皮脂酶抑制活性的噁二唑衍生物
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
RU2013114390A (ru) 2010-08-31 2014-10-10 СНУ Ар энд ДиБи ФАУНДЕЙШН Применение фетального репрограммирования посредством ppar-дельта-агониста
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US9321787B2 (en) * 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
CA2996681C (en) * 2015-08-27 2024-04-09 Auckland Uniservices Limited Inhibitors of tryptophan dioxygenases (ido1 and tdo) and their use in therapy
KR102919209B1 (ko) 2018-08-10 2026-01-28 다이아핀 테라퓨틱스, 엘엘씨 트리-펩타이드 그리고 대사, 심장혈관 및 염증성 장애의 치료

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003051841A2 (en) * 2001-12-14 2003-06-26 Novo Nordisk A/S Compounds and uses thereof for decreasing activity of hormone-sensitive lipase

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU221138B1 (en) * 1994-08-30 2002-08-28 Sankyo Co Condensed isoxazolyloxy- and -thioalkylamine derivatives, process for the preparation thereof and pharmaceutical compositions containing them
US20030114420A1 (en) * 2000-06-28 2003-06-19 Salvati Mark E. Fused cyclic modulators of nuclear hormone receptor function
MXPA03006936A (es) * 2001-02-02 2003-11-18 Pfizer Tratamiento de diabetes mellitus.
AU2001274426A1 (en) 2001-07-04 2003-01-21 Akodi S.A. Web windowed graphical user interface
JP2003033007A (ja) 2001-07-09 2003-01-31 Sanyo Electric Co Ltd チャージポンプ回路の制御方法
US7226919B2 (en) 2002-12-18 2007-06-05 Vertex Pharmaceuticals Inc. Compositions useful as inhibitors of protein kinases
EP1613608A1 (en) * 2003-04-01 2006-01-11 Eli Lilly And Company Phospholipase inhibitors
EP1615900A1 (en) * 2003-04-01 2006-01-18 Eli Lilly And Company Benzisothiazol-3-one-carboxylic acid amides as phospholipase inhibitors
US20070197610A1 (en) * 2004-03-16 2007-08-23 Janssen Pharmaceutica N.V. Benzisoxazoles
TW200633990A (en) * 2004-11-18 2006-10-01 Takeda Pharmaceuticals Co Amide compound

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003051841A2 (en) * 2001-12-14 2003-06-26 Novo Nordisk A/S Compounds and uses thereof for decreasing activity of hormone-sensitive lipase
WO2003051842A2 (en) * 2001-12-14 2003-06-26 Novo Nordisk A/S Compositions decreasing activity of hormone-sensitive lipase

Also Published As

Publication number Publication date
BRPI0608495A2 (pt) 2010-01-05
EP1874741A1 (de) 2008-01-09
RU2414458C2 (ru) 2011-03-20
NZ562694A (en) 2010-05-28
CN101160293A (zh) 2008-04-09
ZA200707929B (en) 2008-12-31
JP2008536884A (ja) 2008-09-11
MA29393B1 (fr) 2008-04-01
CA2606301A1 (en) 2006-10-26
IL186635A0 (en) 2008-01-20
AU2006237127A1 (en) 2006-10-26
KR20080004501A (ko) 2008-01-09
WO2006111321A1 (de) 2006-10-26
AR053228A1 (es) 2007-04-25
MX2007012732A (es) 2008-03-14
NO20075938L (no) 2007-11-19
US8921404B2 (en) 2014-12-30
RU2007142657A (ru) 2009-05-27
TW200722421A (en) 2007-06-16
US20080090867A1 (en) 2008-04-17
MY142441A (en) 2010-11-30

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Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
8127 New person/name/address of the applicant

Owner name: SANOFI-AVENTIS, PARIS, FR

8130 Withdrawal