DE102004053407A1 - Acylierte Nonadepsipeptide II - Google Patents

Acylierte Nonadepsipeptide II Download PDF

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Publication number
DE102004053407A1
DE102004053407A1 DE102004053407A DE102004053407A DE102004053407A1 DE 102004053407 A1 DE102004053407 A1 DE 102004053407A1 DE 102004053407 A DE102004053407 A DE 102004053407A DE 102004053407 A DE102004053407 A DE 102004053407A DE 102004053407 A1 DE102004053407 A1 DE 102004053407A1
Authority
DE
Germany
Prior art keywords
hplc
compound
mmol
compounds
eluent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102004053407A
Other languages
German (de)
English (en)
Inventor
Franz von Dr. Nussbaum
Nina Dr. Brunner
Rainer Dr. Endermann
Chantal Dr. Fürstner
Elke Dr. Hartmann
Holger Dr. Paulsen
Jacques Dr. Ragot
Guido Dr. Schiffer
Joachim Dr. Schuhmacher
Niels Dr. Svenstrup
Joachim Dr. Telser
Sonja Anlauf
Michael-Alexander Dr. Brüning
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aicuris GmbH and Co KG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Priority to DE102004053407A priority Critical patent/DE102004053407A1/de
Priority to ZA200703674A priority patent/ZA200703674B/xx
Priority to NZ554813A priority patent/NZ554813A/en
Priority to BRPI0516677-2A priority patent/BRPI0516677A/pt
Priority to AU2005300815A priority patent/AU2005300815B2/en
Priority to RU2007120686/04A priority patent/RU2414477C2/ru
Priority to PCT/EP2005/011363 priority patent/WO2006048139A1/de
Priority to CA002586704A priority patent/CA2586704A1/en
Priority to CNA2005800371138A priority patent/CN101056887A/zh
Priority to KR1020077010212A priority patent/KR20070083984A/ko
Priority to JP2007539492A priority patent/JP4843614B2/ja
Priority to EP05798234A priority patent/EP1807443A1/de
Priority to UAA200705852A priority patent/UA89800C2/ru
Priority to MX2007005382A priority patent/MX2007005382A/es
Priority to GT200500308A priority patent/GT200500308A/es
Priority to MYPI20055197A priority patent/MY145448A/en
Priority to ARP050104586A priority patent/AR053775A1/es
Priority to UY29189A priority patent/UY29189A1/es
Priority to HN2005030779A priority patent/HN2005030779A/es
Priority to US11/267,063 priority patent/US7531507B2/en
Priority to SV2005002290A priority patent/SV2006002290A/es
Priority to TW094138656A priority patent/TW200621799A/zh
Priority to PE2005001295A priority patent/PE20060942A1/es
Publication of DE102004053407A1 publication Critical patent/DE102004053407A1/de
Priority to CR9079A priority patent/CR9079A/es
Priority to IL182739A priority patent/IL182739A/en
Priority to MA29955A priority patent/MA29218B1/fr
Priority to NO20072854A priority patent/NO20072854L/no
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K11/00Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE102004053407A 2004-11-05 2004-11-05 Acylierte Nonadepsipeptide II Withdrawn DE102004053407A1 (de)

Priority Applications (27)

Application Number Priority Date Filing Date Title
DE102004053407A DE102004053407A1 (de) 2004-11-05 2004-11-05 Acylierte Nonadepsipeptide II
MX2007005382A MX2007005382A (es) 2004-11-05 2005-10-22 Nonadepsipeptidos acilados como derivados de lisobactina.
JP2007539492A JP4843614B2 (ja) 2004-11-05 2005-10-22 アシル化ノナデプシペプチドii
BRPI0516677-2A BRPI0516677A (pt) 2004-11-05 2005-10-22 nonadepsipeptìdeos acilados como derivados de lysobactin
AU2005300815A AU2005300815B2 (en) 2004-11-05 2005-10-22 Acylated nonadepsipeptides used as lysobactin derivatives
RU2007120686/04A RU2414477C2 (ru) 2004-11-05 2005-10-22 Ацилированные нонадепсипептиды в качестве производных лизобактина
PCT/EP2005/011363 WO2006048139A1 (de) 2004-11-05 2005-10-22 Acylierte nonadepsipeptide als lysobactinderivate
CA002586704A CA2586704A1 (en) 2004-11-05 2005-10-22 Acylated nonadepsipeptides used as lysobactin derivatives
CNA2005800371138A CN101056887A (zh) 2004-11-05 2005-10-22 用作溶杆菌素衍生物的酰化九酯肽类
KR1020077010212A KR20070083984A (ko) 2004-11-05 2005-10-22 리소박틴 유도체로서 사용되는 아실화 노나뎁시펩티드
NZ554813A NZ554813A (en) 2004-11-05 2005-10-22 Acylated nonadepsipeptides used as lysobactin derivatives
EP05798234A EP1807443A1 (de) 2004-11-05 2005-10-22 Acylierte nonadepsipeptide als lysobactinderivate
UAA200705852A UA89800C2 (en) 2004-11-05 2005-10-22 Acylated nonadepsipeptides used as lysobactin derivatives
ZA200703674A ZA200703674B (en) 2004-11-05 2005-10-22 Acylated nonadepsipeptides used as lysobactin derivatives
GT200500308A GT200500308A (es) 2004-11-05 2005-10-27 Nonadepsipeptidos acilados ii
MYPI20055197A MY145448A (en) 2004-11-05 2005-11-02 Acylated nonadepsipeptides used as lysobactin derivatives
ARP050104586A AR053775A1 (es) 2004-11-05 2005-11-02 Nonadepsipeptidos acilados ii
UY29189A UY29189A1 (es) 2004-11-05 2005-11-03 Nonadepsipeptidos acilados ii
HN2005030779A HN2005030779A (es) 2004-11-05 2005-11-03 Nonadepsipeptidos acilados ii
SV2005002290A SV2006002290A (es) 2004-11-05 2005-11-04 Nonadepsipeptidos acilados ii ref. bhc041327-sv
US11/267,063 US7531507B2 (en) 2004-11-05 2005-11-04 Acylated nonadepsipeptides containing pyridyl alanine residues
TW094138656A TW200621799A (en) 2004-11-05 2005-11-04 Acylated nonadepsipeptides II
PE2005001295A PE20060942A1 (es) 2004-11-05 2005-11-04 Derivados nonadepsipeptidos acilados ii como agentes bactericidas
CR9079A CR9079A (es) 2004-11-05 2007-04-20 Nonadepsipeptidos acilados como derivados de lisobactina
IL182739A IL182739A (en) 2004-11-05 2007-04-23 Acylated nonadepsipeptides used as lysobactin derivatives
MA29955A MA29218B1 (fr) 2004-11-05 2007-05-30 Nonadepsipeptides acyles sous forme de derives de lysobactine
NO20072854A NO20072854L (no) 2004-11-05 2007-06-05 Acylerte nonadepsipeptider anvendt som lysobaktinderivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004053407A DE102004053407A1 (de) 2004-11-05 2004-11-05 Acylierte Nonadepsipeptide II

Publications (1)

Publication Number Publication Date
DE102004053407A1 true DE102004053407A1 (de) 2006-05-11

Family

ID=35462537

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102004053407A Withdrawn DE102004053407A1 (de) 2004-11-05 2004-11-05 Acylierte Nonadepsipeptide II

Country Status (27)

Country Link
US (1) US7531507B2 (ja)
EP (1) EP1807443A1 (ja)
JP (1) JP4843614B2 (ja)
KR (1) KR20070083984A (ja)
CN (1) CN101056887A (ja)
AR (1) AR053775A1 (ja)
AU (1) AU2005300815B2 (ja)
BR (1) BRPI0516677A (ja)
CA (1) CA2586704A1 (ja)
CR (1) CR9079A (ja)
DE (1) DE102004053407A1 (ja)
GT (1) GT200500308A (ja)
HN (1) HN2005030779A (ja)
IL (1) IL182739A (ja)
MA (1) MA29218B1 (ja)
MX (1) MX2007005382A (ja)
MY (1) MY145448A (ja)
NO (1) NO20072854L (ja)
NZ (1) NZ554813A (ja)
PE (1) PE20060942A1 (ja)
RU (1) RU2414477C2 (ja)
SV (1) SV2006002290A (ja)
TW (1) TW200621799A (ja)
UA (1) UA89800C2 (ja)
UY (1) UY29189A1 (ja)
WO (1) WO2006048139A1 (ja)
ZA (1) ZA200703674B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004051025A1 (de) * 2004-10-20 2006-04-27 Bayer Healthcare Ag Substituierte Nonadepsipeptide
DE102004051024A1 (de) * 2004-10-20 2006-04-27 Bayer Healthcare Ag Heterocyclyl-substituierte Nonadepsipeptide
DE102004051023A1 (de) * 2004-10-20 2006-05-04 Bayer Healthcare Ag Desoxo-Nonadepsipeptide
DE102004053410A1 (de) * 2004-11-05 2006-05-11 Bayer Healthcare Ag Cyclische Nonadepsipeptidamide
DE102006003443A1 (de) * 2006-01-25 2007-07-26 Aicuris Gmbh & Co. Kg Asparagin-10-substituierte Nonadepsipeptide
DE102006018250A1 (de) * 2006-04-13 2007-10-18 Aicuris Gmbh & Co. Kg Verfahren zum Herstellen von cyclischen Depsipeptiden
DE102006018080A1 (de) * 2006-04-13 2007-10-18 Aicuris Gmbh & Co. Kg Lysobactinamide
TW201717991A (zh) * 2015-08-17 2017-06-01 拜耳動物保健有限公司 用於治療牛乳房炎之溶桿菌素
EP3363452A1 (en) 2017-02-17 2018-08-22 Bayer Animal Health GmbH Combinations of lysobactin and aminogylcosides against diseases caused by gram-positive and gram-negative bacteria in non-human animals

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1266247A (en) 1985-03-25 1990-02-27 Adrienne A. Tymiak Antibiotic prepared from lysobacter sp. sc 14,067
JPH01132600A (ja) 1987-11-17 1989-05-25 Shionogi & Co Ltd カタノシンaおよびbならびにその製造法
DE10320781A1 (de) * 2003-05-09 2004-11-25 Bayer Healthcare Ag Acylierte Nonadepsipeptide

Also Published As

Publication number Publication date
HN2005030779A (es) 2010-08-19
UY29189A1 (es) 2006-06-30
NZ554813A (en) 2009-11-27
BRPI0516677A (pt) 2008-09-16
MX2007005382A (es) 2007-08-14
IL182739A (en) 2013-03-24
MY145448A (en) 2012-02-15
GT200500308A (es) 2006-06-02
SV2006002290A (es) 2006-10-13
JP4843614B2 (ja) 2011-12-21
PE20060942A1 (es) 2006-10-20
ZA200703674B (en) 2008-09-25
IL182739A0 (en) 2007-07-24
UA89800C2 (en) 2010-03-10
WO2006048139A1 (de) 2006-05-11
CA2586704A1 (en) 2006-05-11
NO20072854L (no) 2007-08-01
CN101056887A (zh) 2007-10-17
MA29218B1 (fr) 2008-02-01
AR053775A1 (es) 2007-05-23
JP2008518982A (ja) 2008-06-05
RU2007120686A (ru) 2008-12-10
EP1807443A1 (de) 2007-07-18
CR9079A (es) 2007-08-28
US7531507B2 (en) 2009-05-12
AU2005300815A1 (en) 2006-05-11
KR20070083984A (ko) 2007-08-24
RU2414477C2 (ru) 2011-03-20
US20060264358A1 (en) 2006-11-23
TW200621799A (en) 2006-07-01
AU2005300815B2 (en) 2011-05-19

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: AICURIS GMBH & CO. KG, 42117 WUPPERTAL, DE

R120 Application withdrawn or ip right abandoned
R012 Request for examination validly filed

Effective date: 20111012

R120 Application withdrawn or ip right abandoned

Effective date: 20111205