UA89800C2 - Acylated nonadepsipeptides used as lysobactin derivatives - Google Patents

Acylated nonadepsipeptides used as lysobactin derivatives

Info

Publication number
UA89800C2
UA89800C2 UAA200705852A UAA200705852A UA89800C2 UA 89800 C2 UA89800 C2 UA 89800C2 UA A200705852 A UAA200705852 A UA A200705852A UA A200705852 A UAA200705852 A UA A200705852A UA 89800 C2 UA89800 C2 UA 89800C2
Authority
UA
Ukraine
Prior art keywords
nonadepsipeptides
acylated
lysobactin derivatives
lysobactin
derivatives
Prior art date
Application number
UAA200705852A
Other languages
English (en)
Ukrainian (uk)
Inventor
НУССБАУМ Франц ФОН
Нина Бруннер
Райнер Эндерманн
Шанталь Фюрстнер
Эльке Хартманн
Хольгер Паульсен
Жак Раго
Гуидо Шиффер
Йоахим Шумахер
Нильс Свенструп
Йоахим Тельсер
Соня АНЛАУФ
Михаэль-Александер Брюнинг
Original Assignee
Аикурис Гмбх & Ко. Кг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аикурис Гмбх & Ко. Кг filed Critical Аикурис Гмбх & Ко. Кг
Publication of UA89800C2 publication Critical patent/UA89800C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

В заявке описаны нонадепсипептиды (производные лизобактина), способ их получения, а также их применение для приготовления лекарственных средств, предназначенных для лечения и/или профилактики разных болезней, прежде всего инфекционных болезней, которые вызываются бактериями.Подобные производные лизобактина отличаются от природного вещества наличием N-концевого отрезка пептидной цепи, который содержит 3-(3-пиридил)аланильный остаток.
UAA200705852A 2004-11-05 2005-10-22 Acylated nonadepsipeptides used as lysobactin derivatives UA89800C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004053407A DE102004053407A1 (de) 2004-11-05 2004-11-05 Acylierte Nonadepsipeptide II

Publications (1)

Publication Number Publication Date
UA89800C2 true UA89800C2 (en) 2010-03-10

Family

ID=35462537

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200705852A UA89800C2 (en) 2004-11-05 2005-10-22 Acylated nonadepsipeptides used as lysobactin derivatives

Country Status (27)

Country Link
US (1) US7531507B2 (ru)
EP (1) EP1807443A1 (ru)
JP (1) JP4843614B2 (ru)
KR (1) KR20070083984A (ru)
CN (1) CN101056887A (ru)
AR (1) AR053775A1 (ru)
AU (1) AU2005300815B2 (ru)
BR (1) BRPI0516677A (ru)
CA (1) CA2586704A1 (ru)
CR (1) CR9079A (ru)
DE (1) DE102004053407A1 (ru)
GT (1) GT200500308A (ru)
HN (1) HN2005030779A (ru)
IL (1) IL182739A (ru)
MA (1) MA29218B1 (ru)
MX (1) MX2007005382A (ru)
MY (1) MY145448A (ru)
NO (1) NO20072854L (ru)
NZ (1) NZ554813A (ru)
PE (1) PE20060942A1 (ru)
RU (1) RU2414477C2 (ru)
SV (1) SV2006002290A (ru)
TW (1) TW200621799A (ru)
UA (1) UA89800C2 (ru)
UY (1) UY29189A1 (ru)
WO (1) WO2006048139A1 (ru)
ZA (1) ZA200703674B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004051025A1 (de) * 2004-10-20 2006-04-27 Bayer Healthcare Ag Substituierte Nonadepsipeptide
DE102004051024A1 (de) * 2004-10-20 2006-04-27 Bayer Healthcare Ag Heterocyclyl-substituierte Nonadepsipeptide
DE102004051023A1 (de) * 2004-10-20 2006-05-04 Bayer Healthcare Ag Desoxo-Nonadepsipeptide
DE102004053410A1 (de) * 2004-11-05 2006-05-11 Bayer Healthcare Ag Cyclische Nonadepsipeptidamide
DE102006003443A1 (de) * 2006-01-25 2007-07-26 Aicuris Gmbh & Co. Kg Asparagin-10-substituierte Nonadepsipeptide
DE102006018250A1 (de) * 2006-04-13 2007-10-18 Aicuris Gmbh & Co. Kg Verfahren zum Herstellen von cyclischen Depsipeptiden
DE102006018080A1 (de) * 2006-04-13 2007-10-18 Aicuris Gmbh & Co. Kg Lysobactinamide
TW201717991A (zh) * 2015-08-17 2017-06-01 拜耳動物保健有限公司 用於治療牛乳房炎之溶桿菌素
EP3363452A1 (en) 2017-02-17 2018-08-22 Bayer Animal Health GmbH Combinations of lysobactin and aminogylcosides against diseases caused by gram-positive and gram-negative bacteria in non-human animals

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1266247A (en) 1985-03-25 1990-02-27 Adrienne A. Tymiak Antibiotic prepared from lysobacter sp. sc 14,067
JPH01132600A (ja) 1987-11-17 1989-05-25 Shionogi & Co Ltd カタノシンａおよびｂならびにその製造法
DE10320781A1 (de) * 2003-05-09 2004-11-25 Bayer Healthcare Ag Acylierte Nonadepsipeptide

Also Published As

Publication number Publication date
HN2005030779A (es) 2010-08-19
UY29189A1 (es) 2006-06-30
NZ554813A (en) 2009-11-27
BRPI0516677A (pt) 2008-09-16
MX2007005382A (es) 2007-08-14
IL182739A (en) 2013-03-24
MY145448A (en) 2012-02-15
GT200500308A (es) 2006-06-02
DE102004053407A1 (de) 2006-05-11
SV2006002290A (es) 2006-10-13
JP4843614B2 (ja) 2011-12-21
PE20060942A1 (es) 2006-10-20
ZA200703674B (en) 2008-09-25
IL182739A0 (en) 2007-07-24
WO2006048139A1 (de) 2006-05-11
CA2586704A1 (en) 2006-05-11
NO20072854L (no) 2007-08-01
CN101056887A (zh) 2007-10-17
MA29218B1 (fr) 2008-02-01
AR053775A1 (es) 2007-05-23
JP2008518982A (ja) 2008-06-05
RU2007120686A (ru) 2008-12-10
EP1807443A1 (de) 2007-07-18
CR9079A (es) 2007-08-28
US7531507B2 (en) 2009-05-12
AU2005300815A1 (en) 2006-05-11
KR20070083984A (ko) 2007-08-24
RU2414477C2 (ru) 2011-03-20
US20060264358A1 (en) 2006-11-23
TW200621799A (en) 2006-07-01
AU2005300815B2 (en) 2011-05-19

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