DE10024788A1 - Stabilitäts-, Biokompatibilitäts-optimiertes Adjuvans (SBA) zur Erhöhung der humoralen und zellulären Immunantwort - Google Patents

Stabilitäts-, Biokompatibilitäts-optimiertes Adjuvans (SBA) zur Erhöhung der humoralen und zellulären Immunantwort

Info

Publication number
DE10024788A1
DE10024788A1 DE10024788A DE10024788A DE10024788A1 DE 10024788 A1 DE10024788 A1 DE 10024788A1 DE 10024788 A DE10024788 A DE 10024788A DE 10024788 A DE10024788 A DE 10024788A DE 10024788 A1 DE10024788 A1 DE 10024788A1
Authority
DE
Germany
Prior art keywords
sba
composition according
particles
oil
adjuvant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE10024788A
Other languages
German (de)
English (en)
Inventor
Rainer Helmut Mueller
Nikolaus Grubhofer
Carsten Olbrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GERBU GmbH
Pharmasol GmbH
Original Assignee
GERBU GmbH
Pharmasol GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GERBU GmbH, Pharmasol GmbH filed Critical GERBU GmbH
Priority to DE10024788A priority Critical patent/DE10024788A1/de
Publication of DE10024788A1 publication Critical patent/DE10024788A1/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
DE10024788A 1999-05-20 2000-05-19 Stabilitäts-, Biokompatibilitäts-optimiertes Adjuvans (SBA) zur Erhöhung der humoralen und zellulären Immunantwort Ceased DE10024788A1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE10024788A DE10024788A1 (de) 1999-05-20 2000-05-19 Stabilitäts-, Biokompatibilitäts-optimiertes Adjuvans (SBA) zur Erhöhung der humoralen und zellulären Immunantwort

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19923256 1999-05-20
DE10024788A DE10024788A1 (de) 1999-05-20 2000-05-19 Stabilitäts-, Biokompatibilitäts-optimiertes Adjuvans (SBA) zur Erhöhung der humoralen und zellulären Immunantwort

Publications (1)

Publication Number Publication Date
DE10024788A1 true DE10024788A1 (de) 2000-11-23

Family

ID=7908697

Family Applications (1)

Application Number Title Priority Date Filing Date
DE10024788A Ceased DE10024788A1 (de) 1999-05-20 2000-05-19 Stabilitäts-, Biokompatibilitäts-optimiertes Adjuvans (SBA) zur Erhöhung der humoralen und zellulären Immunantwort

Country Status (11)

Country Link
EP (1) EP1183045A2 (ja)
JP (1) JP2003500365A (ja)
KR (1) KR20020012221A (ja)
AU (2) AU5214200A (ja)
BR (1) BR0010823A (ja)
CA (1) CA2373239A1 (ja)
DE (1) DE10024788A1 (ja)
MX (1) MXPA01011660A (ja)
TR (1) TR200103333T2 (ja)
WO (2) WO2000071154A2 (ja)
ZA (1) ZA200109147B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000071154A2 (de) * 1999-05-20 2000-11-30 Pharmasol Gmbh Stabilitäts-, biokompatibilitäts-optimiertes adjuvans (sba) zur erhöhung der humoralen und zellulären immunantwort
WO2017097783A1 (en) * 2015-12-08 2017-06-15 Glaxosmithkline Biologicals S.A. Novel adjuvant formulations

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US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
ES2425392T3 (es) 2002-03-20 2013-10-15 Mannkind Corporation Cartucho para un aparato de inhalación
JP2007509164A (ja) * 2003-10-23 2007-04-12 カイロン コーポレイション 安定化組成物
FR2873386B1 (fr) 2004-07-22 2011-01-14 Agence Francaise De Securite Sanitaire Des Aliments Afssa Composition vaccinale contre le rhodococcus equi
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
PL1791542T3 (pl) 2004-08-23 2015-11-30 Mannkind Corp Sole diketopiperazyny do dostarczania leków
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
EP2497484A3 (en) 2006-02-22 2012-11-07 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DK2570147T3 (da) 2008-06-13 2018-01-29 Mannkind Corp Tørpulverinhalator og system til lægemiddelindgivelse
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
MY180552A (en) 2011-04-01 2020-12-02 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
EP2844195B1 (en) 2012-04-30 2019-03-20 Össur HF Prosthetic device, system and method for increasing vacuum attachment
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19745950A1 (de) * 1997-10-17 1999-04-22 Dds Drug Delivery Service Ges Arzneistoffträgerpartikel für die gewebespezifische Arzneistoffapplikation
EP1100464A1 (en) * 1998-07-31 2001-05-23 Korea Institute Of Science And Technology Lipid emulsion and solid lipid nanoparticle as a gene or drug carrier
AU5214200A (en) * 1999-05-20 2000-12-12 Pharmasol Gmbh Stability, biocompatibility optimized adjuvant (sba) for enhancing humoral and cellular immune response

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000071154A2 (de) * 1999-05-20 2000-11-30 Pharmasol Gmbh Stabilitäts-, biokompatibilitäts-optimiertes adjuvans (sba) zur erhöhung der humoralen und zellulären immunantwort
WO2000071154A3 (de) * 1999-05-20 2001-06-28 Pharmasol Gmbh Stabilitäts-, biokompatibilitäts-optimiertes adjuvans (sba) zur erhöhung der humoralen und zellulären immunantwort
WO2017097783A1 (en) * 2015-12-08 2017-06-15 Glaxosmithkline Biologicals S.A. Novel adjuvant formulations
BE1024228B1 (fr) * 2015-12-08 2017-12-21 Glaxosmithkline Biologicals Sa Nouvelles formulations d'adjuvants

Also Published As

Publication number Publication date
ZA200109147B (en) 2002-05-08
TR200103333T2 (tr) 2002-04-22
CA2373239A1 (en) 2000-11-30
BR0010823A (pt) 2002-03-05
KR20020012221A (ko) 2002-02-15
AU5809100A (en) 2000-12-12
WO2000071154A2 (de) 2000-11-30
AU5214200A (en) 2000-12-12
MXPA01011660A (es) 2004-04-05
WO2000071154A3 (de) 2001-06-28
EP1183045A2 (de) 2002-03-06
WO2000071077A2 (en) 2000-11-30
JP2003500365A (ja) 2003-01-07

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Legal Events

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OP8 Request for examination as to paragraph 44 patent law
8131 Rejection