DE08868549T1 - Zusammensetzung zur behandlung steriler entzündungen - Google Patents

Zusammensetzung zur behandlung steriler entzündungen Download PDF

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Publication number
DE08868549T1
DE08868549T1 DE08868549T DE08868549T DE08868549T1 DE 08868549 T1 DE08868549 T1 DE 08868549T1 DE 08868549 T DE08868549 T DE 08868549T DE 08868549 T DE08868549 T DE 08868549T DE 08868549 T1 DE08868549 T1 DE 08868549T1
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DE
Germany
Prior art keywords
pharmaceutical composition
use according
selenium
strontium
leucine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE08868549T
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English (en)
Inventor
Thomas Tallberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurofood Oy AB
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Neurofood Oy AB
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Publication date
Application filed by Neurofood Oy AB filed Critical Neurofood Oy AB
Publication of DE08868549T1 publication Critical patent/DE08868549T1/de
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Verwendung von
a) L-Aminosäuren Arginin (Arg) oder Lysin (Lys) und Leucin (Leu),
b) Spurenelementen Chrom (Cr), Zinn (Sn), Selen (Se), Strontium (Sr), Vanadium (V), und Wolfram (W), und
c) Folsäure
zur Herstellung einer pharmazeutischen Zusammensetzung zur Behandlung oder Vorbeugung einer sterilen Entzündung.

Claims (11)

  1. Verwendung von a) L-Aminosäuren Arginin (Arg) oder Lysin (Lys) und Leucin (Leu), b) Spurenelementen Chrom (Cr), Zinn (Sn), Selen (Se), Strontium (Sr), Vanadium (V), und Wolfram (W), und c) Folsäure zur Herstellung einer pharmazeutischen Zusammensetzung zur Behandlung oder Vorbeugung einer sterilen Entzündung.
  2. Verwendung nach Anspruch 1, dadurch gekennzeichnet, dass die pharmazeutische Zusammensetzung weiter Zink (Zn) umfasst.
  3. Verwendung nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass die pharmazeutische Zusammensetzung weiter Mangan (Mn) umfasst.
  4. Verwendung nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, dass die pharmazeutische Zusammensetzung weiter neurogene CNS-Lipide umfasst.
  5. Verwendung nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, dass die pharmazeutische Zusammensetzung Folgendes umfasst: a) jeweils 2 bis 5 g L-Arginin-Hydrochlorid und L-Leucin, b) jeweils 0,5 bis 9 mg Chrom-(Cr), Zinn-(Sn), Selen-(Se), Strontium-(Sr), Vanadium-(V) und Wolfram(W)-Salze und c) 1 bis 2 mg Folsäure.
  6. Verwendung nach einem der Ansprüche 1 bis 5, dadurch gekennzeichnet, dass die pharmazeutische Zusammensetzung in Pulverform vorliegt.
  7. Verwendung nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, dass die pharmazeutische Zusammensetzung in der Form einer funktionellen Nahrungsmittelzusatz-Zusammensetzung vorliegt.
  8. Verwendung nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, dass die sterile Entzündung im Zusammenhang mit Krankheiten, ausgewählt aus einer Gruppe umfassend Fibromyalgie, Crohn'sche Krankheit, Psoriasis und Rheuma, steht.
  9. Pharmazeutische Zusammensetzung, dadurch gekennzeichnet, dass sie als einzige pharmazeutisch aktive Bestandteile Folgendes umfasst: a) L-Aminosäuren Arginin (Arg) oder Lysin (Lys) und Leucin (Leu), b) Spurenelemente Chrom (Cr), Zinn (Sn), Selen (Se), Strontium (Sr), Vanadium (V) und Wolfram (W), Zink (Zn) und Mangan (Mn) und c) Folsäure und d) neurogene CNS-Lipide.
  10. Pharmazeutische Zusammensetzung nach Anspruch 9, dadurch gekennzeichnet, dass sie weiter Serin (Ser) du Isoleucin (Ile) als einzige pharmazeutisch aktive Bestandteile umfasst.
  11. Verfahren zur Behandlung oder Vorbeugung einer sterilen Entzündung, wobei pharmazeutisch aktive Mengen von: a) L-Aminosäuren Arginin (Arg) oder Lysin (Lys) und Leucin (Leu), b) Spurenelementen Chrom (Cr), Zinn (Sn), Selen (Se), Strontium (Sr), Vanadium (V), Wolfram (W) und optional Zink (Zn) und/oder Mangan (Mn) und c) Folsäure und optional d) neurogenen CNS-Lipiden einem Patienten, der diese benötigt, verabreicht werden.
DE08868549T 2007-12-28 2008-12-17 Zusammensetzung zur behandlung steriler entzündungen Pending DE08868549T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20075971 2007-12-28
FI20075971A FI122450B (fi) 2007-12-28 2007-12-28 Koostumus steriilin inflammaation hoitoon
PCT/FI2008/050750 WO2009083643A2 (en) 2007-12-28 2008-12-17 Composition for treating sterile inflammation

Publications (1)

Publication Number Publication Date
DE08868549T1 true DE08868549T1 (de) 2011-03-17

Family

ID=38951666

Family Applications (1)

Application Number Title Priority Date Filing Date
DE08868549T Pending DE08868549T1 (de) 2007-12-28 2008-12-17 Zusammensetzung zur behandlung steriler entzündungen

Country Status (18)

Country Link
US (1) US20100291235A1 (de)
EP (1) EP2234611B1 (de)
JP (1) JP5378406B2 (de)
KR (1) KR20100103856A (de)
CN (1) CN101917983B (de)
AT (1) ATE544450T1 (de)
AU (1) AU2008345508B2 (de)
BR (1) BRPI0821919A2 (de)
DE (1) DE08868549T1 (de)
DK (1) DK2234611T3 (de)
ES (1) ES2381690T3 (de)
FI (1) FI122450B (de)
HK (1) HK1143539A1 (de)
IL (1) IL206596A0 (de)
NZ (3) NZ597976A (de)
PL (1) PL2234611T3 (de)
RU (1) RU2462244C2 (de)
WO (1) WO2009083643A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010359375B2 (en) * 2010-08-18 2014-01-30 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
FI123756B (fi) * 2010-09-21 2013-10-31 Neurofood Ab Oy Parannettu lisäravinne syövän hoitamiseksi tai ennaltaehkäisemiseksi
JP5837315B2 (ja) * 2011-03-25 2015-12-24 イーエヌ大塚製薬株式会社 炎症性疾患用栄養組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0737471A3 (de) * 1995-04-10 2000-12-06 L'oreal Verwendung von Erdalkalimetallsalze als TNF-alpha Inhibitor in einer topischen Zusammensetzung und die so hergestellte Zusammensetzung
RU2156087C1 (ru) * 1999-11-25 2000-09-20 Товарищество с ограниченной ответственностью Фирма "Электронная медицина" Биологически активная добавка
US20040241256A1 (en) * 2002-12-05 2004-12-02 Seymour Ehrenpreis Medicinal compositions & therapeutic methods
ATE460168T1 (de) * 2003-10-17 2010-03-15 Neurofood Ab Oy Nicht-radioaktives strontiummittel zur behandlung von krebs
FI121915B (fi) * 2004-02-06 2011-06-15 Neurofood Ab Oy Koostumus psoriasiksen hoitoon
US20060062859A1 (en) * 2004-08-05 2006-03-23 Kenneth Blum Composition and method to optimize and customize nutritional supplement formulations by measuring genetic and metabolomic contributing factors to disease diagnosis, stratification, prognosis, metabolism, and therapeutic outcomes
US20060241040A1 (en) * 2005-04-06 2006-10-26 Alberto Visintin Methods of treating disorders associated with toll-like receptor 4 (TLR4) signalling
RU2308199C2 (ru) * 2005-05-13 2007-10-20 Закрытое акционерное общество "Компания "Нутритек" (ЗАО "Компания "Нутритек") Продукт энтерального питания "нутриэн гепа"

Also Published As

Publication number Publication date
AU2008345508A1 (en) 2009-07-09
ATE544450T1 (de) 2012-02-15
RU2010130889A (ru) 2012-02-10
CN101917983A (zh) 2010-12-15
DK2234611T3 (da) 2012-05-07
EP2234611B1 (de) 2012-02-08
PL2234611T3 (pl) 2012-07-31
IL206596A0 (en) 2010-12-30
NZ586496A (en) 2012-03-30
AU2008345508B2 (en) 2013-11-14
RU2462244C2 (ru) 2012-09-27
EP2234611A2 (de) 2010-10-06
FI20075971A0 (fi) 2007-12-28
FI20075971A (fi) 2009-06-29
JP5378406B2 (ja) 2013-12-25
WO2009083643A3 (en) 2009-10-29
KR20100103856A (ko) 2010-09-28
WO2009083643A2 (en) 2009-07-09
NZ597976A (en) 2012-08-31
ES2381690T3 (es) 2012-05-30
BRPI0821919A2 (pt) 2015-06-16
JP2011507937A (ja) 2011-03-10
HK1143539A1 (en) 2011-01-07
NZ597977A (en) 2012-08-31
CN101917983B (zh) 2013-08-21
US20100291235A1 (en) 2010-11-18
FI122450B (fi) 2012-01-31

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