DD298051A5 - Verfahren zur herstellung eines therapeutischen agens zur behandlung von verdauungskrankheiten - Google Patents

Verfahren zur herstellung eines therapeutischen agens zur behandlung von verdauungskrankheiten Download PDF

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Publication number
DD298051A5
DD298051A5 DD90343153A DD34315390A DD298051A5 DD 298051 A5 DD298051 A5 DD 298051A5 DD 90343153 A DD90343153 A DD 90343153A DD 34315390 A DD34315390 A DD 34315390A DD 298051 A5 DD298051 A5 DD 298051A5
Authority
DD
German Democratic Republic
Prior art keywords
ethyl
compound
formula
alkyl
hydroxy
Prior art date
Application number
DD90343153A
Other languages
German (de)
English (en)
Inventor
Tanaka Toshizo
Hayashi Shoryo
Morioka Yuko
Ulrich Gebert
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ��@���������@�������k�� filed Critical ��@���������@�������k��
Publication of DD298051A5 publication Critical patent/DD298051A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
DD90343153A 1989-08-16 1990-07-30 Verfahren zur herstellung eines therapeutischen agens zur behandlung von verdauungskrankheiten DD298051A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21018789 1989-08-16

Publications (1)

Publication Number Publication Date
DD298051A5 true DD298051A5 (de) 1992-02-06

Family

ID=16585226

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90343153A DD298051A5 (de) 1989-08-16 1990-07-30 Verfahren zur herstellung eines therapeutischen agens zur behandlung von verdauungskrankheiten

Country Status (18)

Country Link
US (1) US5109003A (es)
EP (1) EP0413278B1 (es)
JP (1) JP2977242B2 (es)
KR (1) KR910004620A (es)
AT (1) ATE144900T1 (es)
AU (1) AU624987B2 (es)
CA (1) CA2023310A1 (es)
DD (1) DD298051A5 (es)
DE (1) DE69029069T2 (es)
DK (1) DK0413278T3 (es)
ES (1) ES2094132T3 (es)
GR (1) GR3021569T3 (es)
HU (1) HU207518B (es)
IE (1) IE902954A1 (es)
IL (1) IL95377A (es)
NZ (1) NZ234896A (es)
PT (1) PT95007A (es)
ZA (1) ZA906446B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0570831A2 (de) * 1992-05-20 1993-11-24 Hoechst Aktiengesellschaft Verwendung von Xanthinderivaten zur Behandlung von Nervenschädigungen nach Unterbrechung der Blutzirkulation
US5354756A (en) * 1993-01-12 1994-10-11 Cell Therapeutics, Inc. Olefin-substituted long chain xanthine compounds
DE4411660A1 (de) * 1994-04-05 1995-10-12 Hoechst Ag Verwendung von Xanthinderivaten zur Reduktion der pathologischen Hyperreagibilität eosinophiler Granulozyten, neue Xanthinverbindungen und Verfahren zu deren Herstellung
US7122207B2 (en) * 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
JPS63225317A (ja) * 1986-10-06 1988-09-20 Hoechst Japan Kk 抗消化性潰瘍剤
IL106861A (en) * 1986-12-31 1997-02-18 Hoechst Roussel Pharma Pentoxifylline metabolites and pharmaceutical formulations containing them for inhibiting the activity of interleukin-1 and leukocyte-derived cytokines
JP2661666B2 (ja) * 1988-02-19 1997-10-08 ヘキスト薬品工業株式会社 抗消化性潰瘍剤

Also Published As

Publication number Publication date
JP2977242B2 (ja) 1999-11-15
HUT54688A (en) 1991-03-28
PT95007A (pt) 1991-04-18
NZ234896A (en) 1993-10-26
CA2023310A1 (en) 1991-02-17
IL95377A (en) 1994-08-26
GR3021569T3 (en) 1997-02-28
ATE144900T1 (de) 1996-11-15
KR910004620A (ko) 1991-03-29
AU624987B2 (en) 1992-06-25
EP0413278B1 (en) 1996-11-06
JPH03163019A (ja) 1991-07-15
US5109003A (en) 1992-04-28
ZA906446B (en) 1991-05-29
AU6101890A (en) 1991-02-21
EP0413278A3 (en) 1992-05-06
HU905000D0 (en) 1991-01-28
IE902954A1 (en) 1991-02-27
DE69029069D1 (de) 1996-12-12
IL95377A0 (en) 1991-06-30
HU207518B (en) 1993-04-28
DE69029069T2 (de) 1997-04-10
DK0413278T3 (da) 1997-04-07
EP0413278A2 (en) 1991-02-20
ES2094132T3 (es) 1997-01-16

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