ES2094132T3 - Uso de derivados de xantina contra la ulcera peptica. - Google Patents
Uso de derivados de xantina contra la ulcera peptica.Info
- Publication number
- ES2094132T3 ES2094132T3 ES90115456T ES90115456T ES2094132T3 ES 2094132 T3 ES2094132 T3 ES 2094132T3 ES 90115456 T ES90115456 T ES 90115456T ES 90115456 T ES90115456 T ES 90115456T ES 2094132 T3 ES2094132 T3 ES 2094132T3
- Authority
- ES
- Spain
- Prior art keywords
- peptica
- ulcera
- xantina
- derivatives against
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Abstract
AGENTES TERAPEUTICOS PARA EL TRATAMIENTO DE ENFERMEDADES DE ULCERA PEPTICA QUE CONTIENEN COMO INGREDIENTE ACTIVO AL MENOS UN COMPUESTO DE FORMULA GENERAL I, EN DONDE UNO DE LOS R1 Y R3 ES (EN DONDE M ES 1-5, R4 REPRESENTA UN GRUPO ALQUILO C1-C4); EL RESTANTE DE R1 O R3 ES HIDROGENO, ALQUENILO C3-C6 O ALQUILO C1-C8, EL CUAL PUEDE ESTAR SUSTITUIDO CON HASTA 2 GRUPOS HIDROXILO O UN GRUPO ALCOXILO C1-C4; Y R2 ES ALQUILO C1-C4.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21018789 | 1989-08-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2094132T3 true ES2094132T3 (es) | 1997-01-16 |
Family
ID=16585226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90115456T Expired - Lifetime ES2094132T3 (es) | 1989-08-16 | 1990-08-11 | Uso de derivados de xantina contra la ulcera peptica. |
Country Status (18)
Country | Link |
---|---|
US (1) | US5109003A (es) |
EP (1) | EP0413278B1 (es) |
JP (1) | JP2977242B2 (es) |
KR (1) | KR910004620A (es) |
AT (1) | ATE144900T1 (es) |
AU (1) | AU624987B2 (es) |
CA (1) | CA2023310A1 (es) |
DD (1) | DD298051A5 (es) |
DE (1) | DE69029069T2 (es) |
DK (1) | DK0413278T3 (es) |
ES (1) | ES2094132T3 (es) |
GR (1) | GR3021569T3 (es) |
HU (1) | HU207518B (es) |
IE (1) | IE902954A1 (es) |
IL (1) | IL95377A (es) |
NZ (1) | NZ234896A (es) |
PT (1) | PT95007A (es) |
ZA (1) | ZA906446B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0570831A2 (de) * | 1992-05-20 | 1993-11-24 | Hoechst Aktiengesellschaft | Verwendung von Xanthinderivaten zur Behandlung von Nervenschädigungen nach Unterbrechung der Blutzirkulation |
US5354756A (en) * | 1993-01-12 | 1994-10-11 | Cell Therapeutics, Inc. | Olefin-substituted long chain xanthine compounds |
DE4411660A1 (de) * | 1994-04-05 | 1995-10-12 | Hoechst Ag | Verwendung von Xanthinderivaten zur Reduktion der pathologischen Hyperreagibilität eosinophiler Granulozyten, neue Xanthinverbindungen und Verfahren zu deren Herstellung |
US7122207B2 (en) * | 1998-05-22 | 2006-10-17 | Bristol-Myers Squibb Company | High drug load acid labile pharmaceutical composition |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3525801A1 (de) * | 1985-07-19 | 1987-01-22 | Hoechst Ag | Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung |
JPS63225317A (ja) * | 1986-10-06 | 1988-09-20 | Hoechst Japan Kk | 抗消化性潰瘍剤 |
IL106861A (en) * | 1986-12-31 | 1997-02-18 | Hoechst Roussel Pharma | Pentoxifylline metabolites and pharmaceutical formulations containing them for inhibiting the activity of interleukin-1 and leukocyte-derived cytokines |
JP2661666B2 (ja) * | 1988-02-19 | 1997-10-08 | ヘキスト薬品工業株式会社 | 抗消化性潰瘍剤 |
-
1990
- 1990-07-30 DD DD90343153A patent/DD298051A5/de not_active IP Right Cessation
- 1990-08-10 JP JP2210334A patent/JP2977242B2/ja not_active Expired - Lifetime
- 1990-08-11 EP EP90115456A patent/EP0413278B1/en not_active Expired - Lifetime
- 1990-08-11 DK DK90115456.7T patent/DK0413278T3/da active
- 1990-08-11 AT AT90115456T patent/ATE144900T1/de not_active IP Right Cessation
- 1990-08-11 DE DE69029069T patent/DE69029069T2/de not_active Expired - Fee Related
- 1990-08-11 ES ES90115456T patent/ES2094132T3/es not_active Expired - Lifetime
- 1990-08-14 US US07/566,756 patent/US5109003A/en not_active Expired - Fee Related
- 1990-08-14 IL IL9537790A patent/IL95377A/en not_active IP Right Cessation
- 1990-08-14 NZ NZ234896A patent/NZ234896A/en unknown
- 1990-08-14 HU HU905000A patent/HU207518B/hu not_active IP Right Cessation
- 1990-08-15 AU AU61018/90A patent/AU624987B2/en not_active Ceased
- 1990-08-15 ZA ZA906446A patent/ZA906446B/xx unknown
- 1990-08-15 IE IE295490A patent/IE902954A1/en unknown
- 1990-08-15 CA CA002023310A patent/CA2023310A1/en not_active Abandoned
- 1990-08-16 KR KR1019900012571A patent/KR910004620A/ko active IP Right Grant
- 1990-08-16 PT PT95007A patent/PT95007A/pt not_active Application Discontinuation
-
1996
- 1996-11-07 GR GR960402903T patent/GR3021569T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP2977242B2 (ja) | 1999-11-15 |
HUT54688A (en) | 1991-03-28 |
PT95007A (pt) | 1991-04-18 |
NZ234896A (en) | 1993-10-26 |
CA2023310A1 (en) | 1991-02-17 |
IL95377A (en) | 1994-08-26 |
GR3021569T3 (en) | 1997-02-28 |
ATE144900T1 (de) | 1996-11-15 |
KR910004620A (ko) | 1991-03-29 |
AU624987B2 (en) | 1992-06-25 |
EP0413278B1 (en) | 1996-11-06 |
JPH03163019A (ja) | 1991-07-15 |
US5109003A (en) | 1992-04-28 |
ZA906446B (en) | 1991-05-29 |
AU6101890A (en) | 1991-02-21 |
EP0413278A3 (en) | 1992-05-06 |
DD298051A5 (de) | 1992-02-06 |
HU905000D0 (en) | 1991-01-28 |
IE902954A1 (en) | 1991-02-27 |
DE69029069D1 (de) | 1996-12-12 |
IL95377A0 (en) | 1991-06-30 |
HU207518B (en) | 1993-04-28 |
DE69029069T2 (de) | 1997-04-10 |
DK0413278T3 (da) | 1997-04-07 |
EP0413278A2 (en) | 1991-02-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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