DD291478A5 - Verfahren zur herstellung eines superfiziellen therapeutischen systems mit einem gehalt an einem antineoplastischen wirkstoff, insbesondere 5-fluoruracil - Google Patents

Verfahren zur herstellung eines superfiziellen therapeutischen systems mit einem gehalt an einem antineoplastischen wirkstoff, insbesondere 5-fluoruracil Download PDF

Info

Publication number
DD291478A5
DD291478A5 DD90337184A DD33718490A DD291478A5 DD 291478 A5 DD291478 A5 DD 291478A5 DD 90337184 A DD90337184 A DD 90337184A DD 33718490 A DD33718490 A DD 33718490A DD 291478 A5 DD291478 A5 DD 291478A5
Authority
DD
German Democratic Republic
Prior art keywords
adhesive
matrix
polyacrylate
fluorouracil
protective layer
Prior art date
Application number
DD90337184A
Other languages
German (de)
English (en)
Inventor
Walter Mueller
Heinrich Kindel
Original Assignee
���@�������@��������`�������@����@�K@��K@��k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ���@�������@��������`�������@����@�K@��K@��k�� filed Critical ���@�������@��������`�������@����@�K@��K@��k��
Publication of DD291478A5 publication Critical patent/DD291478A5/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • General Preparation And Processing Of Foods (AREA)
DD90337184A 1989-01-20 1990-01-18 Verfahren zur herstellung eines superfiziellen therapeutischen systems mit einem gehalt an einem antineoplastischen wirkstoff, insbesondere 5-fluoruracil DD291478A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3901551A DE3901551A1 (de) 1989-01-20 1989-01-20 Superfizielles therapeutisches system mit einem gehalt an einem antineoplastischen wirkstoff, insbesondere 5-fluoruracil

Publications (1)

Publication Number Publication Date
DD291478A5 true DD291478A5 (de) 1991-07-04

Family

ID=6372429

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90337184A DD291478A5 (de) 1989-01-20 1990-01-18 Verfahren zur herstellung eines superfiziellen therapeutischen systems mit einem gehalt an einem antineoplastischen wirkstoff, insbesondere 5-fluoruracil

Country Status (22)

Country Link
US (1) US5077055A (sv)
EP (1) EP0379933B1 (sv)
JP (1) JPH0784378B2 (sv)
KR (1) KR960008226B1 (sv)
AT (1) ATE112174T1 (sv)
AU (1) AU631167B2 (sv)
CA (1) CA2007353C (sv)
CZ (1) CZ278718B6 (sv)
DD (1) DD291478A5 (sv)
DE (2) DE3901551A1 (sv)
DK (1) DK0379933T3 (sv)
ES (1) ES2063172T3 (sv)
FI (1) FI104150B1 (sv)
HU (1) HU205013B (sv)
IE (1) IE66737B1 (sv)
IL (1) IL92924A (sv)
NO (1) NO300617B1 (sv)
NZ (1) NZ232158A (sv)
PL (1) PL163294B1 (sv)
PT (1) PT92903B (sv)
SK (1) SK277778B6 (sv)
YU (1) YU47339B (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4020144A1 (de) * 1990-06-25 1992-01-09 Lohmann Therapie Syst Lts Pflaster mit hohem gehalt an weichmachenden inhaltsstoffen
TW283163B (sv) * 1993-08-19 1996-08-11 Nissan Chemical Ind Ltd
JPH07206710A (ja) * 1994-01-21 1995-08-08 Nitto Denko Corp 経皮投薬用テープ製剤
DE4416927C1 (de) * 1994-05-13 1995-08-31 Lohmann Therapie Syst Lts Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung
FR2738744B1 (fr) * 1995-09-20 1997-10-24 Oreal Patch cosmetique ou dermo-pharmaceutique contenant dans une matrice polymerique au moins un compose actif en particulier instable en milieu oxydant et au moins un agent hydro-absorbant
US6063398A (en) * 1995-09-20 2000-05-16 L'oreal Cosmetic or dermopharmaceutical patch containing, in an anhydrous polymeric matrix, at least one active compound which is, in particular, unstable in oxidizing mediums, and at least one water-absorbing agent
US5882675A (en) * 1996-03-09 1999-03-16 Nitto Denko Corporation Percutaneous absorption preparation
FR2787459B1 (fr) * 1998-12-18 2001-02-16 Oreal Solution d'un polymere du type polyacrylique et/ou polyvinylique associe a une charge et a un agent keratolytique et dispositif cosmetique de nettoyage et de soin
DE19925519A1 (de) * 1999-06-04 2000-12-07 Lohmann Therapie Syst Lts Wundauflage zur gesteuerten Abgabe von Wirkstoff an Wunden und Verfahren zu ihrer Herstellung
DE10025328A1 (de) * 2000-05-23 2001-12-06 Lohmann Therapie Syst Lts Acetylsalicylsäure enthaltendes superfizielles therapeutisches System zur Behandlung von Hautschmerzen
FR2826261B1 (fr) * 2001-06-26 2005-03-25 Lmd Composition a usage topique comprenant un produit cytotoxique et son utilisation dans le traitement de l'alopeche
ITMI20041628A1 (it) * 2004-08-06 2004-11-06 Bouty S P A Sistema terapeutico a rilascio controllato per uso topico transdermico

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3734097A (en) * 1969-04-01 1973-05-22 Alza Corp Therapeutic adhesive tape
US3769071A (en) * 1971-06-04 1973-10-30 Minnesota Mining & Mfg Pressure sensitive adhesive tape comprising 5-fluorouracil
IN155486B (sv) * 1981-03-16 1985-02-09 Johnson & Johnson Prod Inc
JPS60123417A (ja) * 1983-12-07 1985-07-02 Nitto Electric Ind Co Ltd 薬物投与部材
US4697202A (en) * 1984-02-02 1987-09-29 Sri International Integrated circuit having dislocation free substrate
WO1985003878A1 (en) * 1984-03-01 1985-09-12 Sandoz Ag Pharmaceutical compositions
DE3513938A1 (de) * 1985-04-18 1986-10-23 Merck Patent Gmbh, 6100 Darmstadt Cytostatikahaltiges pharmakadepot
EP0224981A3 (en) * 1985-11-04 1988-08-10 Paco Research Corporation Nitroglycerin transdermal delivery system
WO1987007154A1 (en) * 1986-05-29 1987-12-03 Vsesojuzny Nauchno-Issledovatelsky I Ispytatelny I Antitumor film of biodestructible polymers
DE3629304A1 (de) * 1986-08-28 1988-03-24 Lohmann Gmbh & Co Kg Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung
AU607172B2 (en) * 1986-12-22 1991-02-28 Cygnus, Inc. Diffusion matrix for transdermal drug administration
US4855142A (en) * 1987-02-27 1989-08-08 Ciba-Geigy Corporation Pharmaceutical plaster
DE3714140A1 (de) * 1987-04-28 1988-11-10 Lohmann Therapie Syst Lts Wirkstoffhaltiges pflaster zur kontrollierten verabreichung von wirkstoffen an die haut, seine verwendung sowie verfahren zur gesteuerten verabreichung von wirkstoffen an die haut
HU197519B (en) * 1987-06-22 1989-04-28 Biogal Gyogyszergyar Process for producing medicine form capable for penetrating through epidermis and suitable for intaking the agent through epidermis by kinetics of zero-grade
IE65163B1 (en) * 1987-06-29 1995-10-04 Squibb & Sons Inc Process for preparing a wound dressing comprising a hydrophilic acrylic adhesive layer

Also Published As

Publication number Publication date
FI104150B (sv) 1999-11-30
ATE112174T1 (de) 1994-10-15
HU900199D0 (en) 1990-03-28
EP0379933A2 (de) 1990-08-01
ES2063172T3 (es) 1995-01-01
IL92924A (en) 1994-01-25
CA2007353A1 (en) 1990-07-20
IE66737B1 (en) 1996-02-07
DE3901551A1 (de) 1990-07-26
DK0379933T3 (da) 1994-11-21
AU4739089A (en) 1990-07-26
DE3901551C2 (sv) 1992-01-02
JPH02288826A (ja) 1990-11-28
PL163294B1 (pl) 1994-03-31
CA2007353C (en) 1997-08-19
AU631167B2 (en) 1992-11-19
NO900270L (no) 1990-07-23
YU47339B (sh) 1995-01-31
KR960008226B1 (ko) 1996-06-21
PT92903A (pt) 1990-07-31
HU205013B (en) 1992-03-30
IE900212L (en) 1990-07-20
NZ232158A (en) 1991-06-25
CZ278718B6 (en) 1994-05-18
SK13290A3 (en) 1994-12-07
NO900270D0 (no) 1990-01-19
EP0379933B1 (de) 1994-09-28
JPH0784378B2 (ja) 1995-09-13
SK277778B6 (en) 1994-12-07
IL92924A0 (en) 1990-09-17
KR900011458A (ko) 1990-08-01
EP0379933A3 (de) 1991-06-12
CZ13290A3 (en) 1993-10-13
NO300617B1 (no) 1997-06-30
PT92903B (pt) 1995-12-29
HUT55642A (en) 1991-06-28
FI900315A0 (fi) 1990-01-19
DE59007292D1 (de) 1994-11-03
US5077055A (en) 1991-12-31
FI104150B1 (sv) 1999-11-30
YU3390A (sh) 1992-07-20

Similar Documents

Publication Publication Date Title
DE69401945T3 (de) Einarbeitung eines poly-n-vinylamids in ein transdermales system
DE69325495T2 (de) Extrudierbare Zusammensetzungen zur topischen oder transdermalen Wirkstoffabgabe
DE102006026578B4 (de) Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung
EP0376067B1 (de) Transdermales therapeutisches System mit Physostigmin als wirksamen Bestandteil und Verfahren zu seiner Herstellung
DE3910543C2 (sv)
DE69329825T2 (de) Zweiphasenmatrix für ein abgabesystem zur verzögerten arzneistofffreisetzung
DE60304477T2 (de) Verbessertes transdermales abgabesystem für die verabreichung von rotigotin
EP1178782B1 (de) Transdermales therapeutisches system (tts) tolterodin enthaltend
DE60311449T2 (de) Transdermales therapeutisches system mit zwei übereinanderliegenden matrixschichten, die verschiedene affinitäten zum enthaltenen wirkstoff ausweisen
EP2111857A1 (de) Transdermales therapeutisches System zur Verabreichung von Fentanyl oder einem Analogstoff hiervon
DE3901551C2 (sv)
DE3880754T2 (de) Perkutanes Präparat mit kontrollierter Abgabe.
EP0781134A1 (de) Scopolaminpflaster
DD292383A5 (de) Verfahren zur herstellung eines transdermalen systems zur gesteuerten, abgestuften verabreichung von wirkstoffen
EP1303267B1 (de) Dermales applikationssystem für aminolävulinsäure
EP0374725B1 (de) Transdermales therapeutisches System mit Norpseudoephedrin als aktivem Bestandteil
EP0742716B1 (de) Pharmazeutische zusammensetzung zur systemischen transdermalen verabreichung mit dem wirkstoff morphin-6-glucuronid
EP2366388A1 (de) Nicht-okklusives transdermales therapeutisches System zur Verabreichung von Buprenorphin
DE10025971B4 (de) Transdermales therapeutisches System in Plasterform mit verminderter Tendenz zur Wirkstoffkristallisation und seine Verwendung
DE102018118507A1 (de) Transdermales therapeutisches System zur Abgabe von Scopolamin ohne Membran
WO2000013679A1 (de) Arzneistoffhaltiges pflaster mit drei funktionalen schichten
WO2020182378A1 (de) Phenprocoumon-tts

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee