YU3390A - Postupak za izradu površinskog terapijskog sistema sa sadržajem antineoplastične aktivne materije, naročito 5-fluor-uracila - Google Patents

Postupak za izradu površinskog terapijskog sistema sa sadržajem antineoplastične aktivne materije, naročito 5-fluor-uracila

Info

Publication number
YU3390A
YU3390A YU3390A YU3390A YU3390A YU 3390 A YU3390 A YU 3390A YU 3390 A YU3390 A YU 3390A YU 3390 A YU3390 A YU 3390A YU 3390 A YU3390 A YU 3390A
Authority
YU
Yugoslavia
Prior art keywords
fluor
uracil
procedure
development
active substance
Prior art date
Application number
YU3390A
Other languages
English (en)
Other versions
YU47339B (sh
Inventor
W. Mueller
H. Kindel
Original Assignee
Lts Lohmann Therapie-Systeme Gmbh. & Co.Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohmann Therapie-Systeme Gmbh. & Co.Kg. filed Critical Lts Lohmann Therapie-Systeme Gmbh. & Co.Kg.
Priority to SI9010033A priority Critical patent/SI9010033B/sl
Publication of YU3390A publication Critical patent/YU3390A/sh
Priority to HRP-33/90A priority patent/HRP930667B1/xx
Publication of YU47339B publication Critical patent/YU47339B/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

POSTUPAK ZA IZRADU POVRŠINSKOG TERAPIJSKOG SISTEMA SA SADRŽAJEM ANTINEOPLASTIČNE AKTIVNE MATERIJE, NAROČITO 5-FLUOR-URACILA, koji se sastoji od nepropusnog zadnjeg sloja, matriksa koji sadrži aktivnu materiju i ponova odvojivog zaštitnog sloja, koji je naznačen time, što se sledeći sastojci matriksa a) antineoplatična aktivna materija b) samolepljivi poliakrilat c) absorber vode, i u datom slučaju d) hidrofilni poliakrilat koji nije lepljiv, e) omekšivač i/ili ubrzivač penetracije izmešaju homogeno, u datom slučaju rastvaranjem u rastvaraču, homogena smeša nanese na nepropusan zadnji sloj, u datom slučaju odstrani rastvarač i posle toga se sloj matriksa pokriva sa zaštitnim slojem.
YU3390A 1989-01-20 1990-01-09 Postupak za izradu površinskog terapijskog sistema sa sadržajem antineoplastične aktivne materije, naročito 5-fluoruracila YU47339B (sh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI9010033A SI9010033B (sl) 1989-01-20 1990-01-09 Postopek za izdelavo površinskega terapevtskega sistema z vsebino antineoplastične dejavne snovi, zlasti 5-fluoruracila
HRP-33/90A HRP930667B1 (en) 1989-01-20 1993-04-01 Process for the production of a superficial therapeutic system consisting of an antineoplastic active substance, particularly fluorouracil

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3901551A DE3901551A1 (de) 1989-01-20 1989-01-20 Superfizielles therapeutisches system mit einem gehalt an einem antineoplastischen wirkstoff, insbesondere 5-fluoruracil

Publications (2)

Publication Number Publication Date
YU3390A true YU3390A (sh) 1992-07-20
YU47339B YU47339B (sh) 1995-01-31

Family

ID=6372429

Family Applications (1)

Application Number Title Priority Date Filing Date
YU3390A YU47339B (sh) 1989-01-20 1990-01-09 Postupak za izradu površinskog terapijskog sistema sa sadržajem antineoplastične aktivne materije, naročito 5-fluoruracila

Country Status (22)

Country Link
US (1) US5077055A (sh)
EP (1) EP0379933B1 (sh)
JP (1) JPH0784378B2 (sh)
KR (1) KR960008226B1 (sh)
AT (1) ATE112174T1 (sh)
AU (1) AU631167B2 (sh)
CA (1) CA2007353C (sh)
CZ (1) CZ278718B6 (sh)
DD (1) DD291478A5 (sh)
DE (2) DE3901551A1 (sh)
DK (1) DK0379933T3 (sh)
ES (1) ES2063172T3 (sh)
FI (1) FI104150B1 (sh)
HU (1) HU205013B (sh)
IE (1) IE66737B1 (sh)
IL (1) IL92924A (sh)
NO (1) NO300617B1 (sh)
NZ (1) NZ232158A (sh)
PL (1) PL163294B1 (sh)
PT (1) PT92903B (sh)
SK (1) SK277778B6 (sh)
YU (1) YU47339B (sh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4020144A1 (de) * 1990-06-25 1992-01-09 Lohmann Therapie Syst Lts Pflaster mit hohem gehalt an weichmachenden inhaltsstoffen
TW283163B (sh) * 1993-08-19 1996-08-11 Nissan Chemical Ind Ltd
JPH07206710A (ja) * 1994-01-21 1995-08-08 Nitto Denko Corp 経皮投薬用テープ製剤
DE4416927C1 (de) * 1994-05-13 1995-08-31 Lohmann Therapie Syst Lts Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung
FR2738744B1 (fr) * 1995-09-20 1997-10-24 Oreal Patch cosmetique ou dermo-pharmaceutique contenant dans une matrice polymerique au moins un compose actif en particulier instable en milieu oxydant et au moins un agent hydro-absorbant
US6063398A (en) * 1995-09-20 2000-05-16 L'oreal Cosmetic or dermopharmaceutical patch containing, in an anhydrous polymeric matrix, at least one active compound which is, in particular, unstable in oxidizing mediums, and at least one water-absorbing agent
US5882675A (en) * 1996-03-09 1999-03-16 Nitto Denko Corporation Percutaneous absorption preparation
FR2787459B1 (fr) * 1998-12-18 2001-02-16 Oreal Solution d'un polymere du type polyacrylique et/ou polyvinylique associe a une charge et a un agent keratolytique et dispositif cosmetique de nettoyage et de soin
DE19925519A1 (de) * 1999-06-04 2000-12-07 Lohmann Therapie Syst Lts Wundauflage zur gesteuerten Abgabe von Wirkstoff an Wunden und Verfahren zu ihrer Herstellung
DE10025328A1 (de) * 2000-05-23 2001-12-06 Lohmann Therapie Syst Lts Acetylsalicylsäure enthaltendes superfizielles therapeutisches System zur Behandlung von Hautschmerzen
FR2826261B1 (fr) * 2001-06-26 2005-03-25 Lmd Composition a usage topique comprenant un produit cytotoxique et son utilisation dans le traitement de l'alopeche
ITMI20041628A1 (it) * 2004-08-06 2004-11-06 Bouty S P A Sistema terapeutico a rilascio controllato per uso topico transdermico

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3734097A (en) * 1969-04-01 1973-05-22 Alza Corp Therapeutic adhesive tape
US3769071A (en) * 1971-06-04 1973-10-30 Minnesota Mining & Mfg Pressure sensitive adhesive tape comprising 5-fluorouracil
IN155486B (sh) * 1981-03-16 1985-02-09 Johnson & Johnson Prod Inc
JPS60123417A (ja) * 1983-12-07 1985-07-02 Nitto Electric Ind Co Ltd 薬物投与部材
US4697202A (en) * 1984-02-02 1987-09-29 Sri International Integrated circuit having dislocation free substrate
WO1985003878A1 (en) * 1984-03-01 1985-09-12 Sandoz Ag Pharmaceutical compositions
DE3513938A1 (de) * 1985-04-18 1986-10-23 Merck Patent Gmbh, 6100 Darmstadt Cytostatikahaltiges pharmakadepot
EP0224981A3 (en) * 1985-11-04 1988-08-10 Paco Research Corporation Nitroglycerin transdermal delivery system
WO1987007154A1 (en) * 1986-05-29 1987-12-03 Vsesojuzny Nauchno-Issledovatelsky I Ispytatelny I Antitumor film of biodestructible polymers
DE3629304A1 (de) * 1986-08-28 1988-03-24 Lohmann Gmbh & Co Kg Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung
AU607172B2 (en) * 1986-12-22 1991-02-28 Cygnus, Inc. Diffusion matrix for transdermal drug administration
US4855142A (en) * 1987-02-27 1989-08-08 Ciba-Geigy Corporation Pharmaceutical plaster
DE3714140A1 (de) * 1987-04-28 1988-11-10 Lohmann Therapie Syst Lts Wirkstoffhaltiges pflaster zur kontrollierten verabreichung von wirkstoffen an die haut, seine verwendung sowie verfahren zur gesteuerten verabreichung von wirkstoffen an die haut
HU197519B (en) * 1987-06-22 1989-04-28 Biogal Gyogyszergyar Process for producing medicine form capable for penetrating through epidermis and suitable for intaking the agent through epidermis by kinetics of zero-grade
IE65163B1 (en) * 1987-06-29 1995-10-04 Squibb & Sons Inc Process for preparing a wound dressing comprising a hydrophilic acrylic adhesive layer

Also Published As

Publication number Publication date
FI104150B (fi) 1999-11-30
ATE112174T1 (de) 1994-10-15
HU900199D0 (en) 1990-03-28
EP0379933A2 (de) 1990-08-01
ES2063172T3 (es) 1995-01-01
IL92924A (en) 1994-01-25
CA2007353A1 (en) 1990-07-20
DD291478A5 (de) 1991-07-04
IE66737B1 (en) 1996-02-07
DE3901551A1 (de) 1990-07-26
DK0379933T3 (da) 1994-11-21
AU4739089A (en) 1990-07-26
DE3901551C2 (sh) 1992-01-02
JPH02288826A (ja) 1990-11-28
PL163294B1 (pl) 1994-03-31
CA2007353C (en) 1997-08-19
AU631167B2 (en) 1992-11-19
NO900270L (no) 1990-07-23
YU47339B (sh) 1995-01-31
KR960008226B1 (ko) 1996-06-21
PT92903A (pt) 1990-07-31
HU205013B (en) 1992-03-30
IE900212L (en) 1990-07-20
NZ232158A (en) 1991-06-25
CZ278718B6 (en) 1994-05-18
SK13290A3 (en) 1994-12-07
NO900270D0 (no) 1990-01-19
EP0379933B1 (de) 1994-09-28
JPH0784378B2 (ja) 1995-09-13
SK277778B6 (en) 1994-12-07
IL92924A0 (en) 1990-09-17
KR900011458A (ko) 1990-08-01
EP0379933A3 (de) 1991-06-12
CZ13290A3 (en) 1993-10-13
NO300617B1 (no) 1997-06-30
PT92903B (pt) 1995-12-29
HUT55642A (en) 1991-06-28
FI900315A0 (fi) 1990-01-19
DE59007292D1 (de) 1994-11-03
US5077055A (en) 1991-12-31
FI104150B1 (fi) 1999-11-30

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